The role of high‐intensity focused ultrasound as a symptomatic treatment for Parkinson's disease

2019 ◽  
Vol 34 (9) ◽  
pp. 1243-1251 ◽  
Author(s):  
Shayan Moosa ◽  
Raul Martínez‐Fernández ◽  
W. Jeffrey Elias ◽  
Marta del Alamo ◽  
Howard M. Eisenberg ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
High Intensity ◽  
Focused Ultrasound ◽  
Symptomatic Treatment ◽  
High Intensity Focused Ultrasound

Reply to: Comment on “The Role of High‐Intensity Focused Ultrasound as a Symptomatic Treatment for Parkinson's Disease”

2020 ◽  
Vol 35 (3) ◽  
pp. 521-522 ◽  
Author(s):  
Shayan Moosa ◽  
Raul Martínez‐Fernández ◽  
W. Jeffrey Elias ◽  
Marta Alamo ◽  
Howard M. Eisenberg ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
High Intensity ◽  
Focused Ultrasound ◽  
Symptomatic Treatment ◽  
High Intensity Focused Ultrasound

scholarly journals Consensus Statement on High-Intensity Focused Ultrasound for Functional Neurosurgery in Switzerland

2021 ◽  
Vol 12 ◽  
Author(s):  
Lennart H. Stieglitz ◽  
Markus F. Oertel ◽  
Ettore A. Accolla ◽  
Julien Bally ◽  
Roland Bauer ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Patient Selection ◽  
Movement Disorders ◽  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Brain Disorders ◽  
Functional Neurosurgery ◽  
Consensus Paper

Background: Magnetic resonance-guided high-intensity focused ultrasound (MRgHiFUS) has evolved into a viable ablative treatment option for functional neurosurgery. However, it is not clear yet, how this new technology should be integrated into current and established clinical practice and a consensus should be found about recommended indications, stereotactic targets, patient selection, and outcome measurements.Objective: To sum up and unify current knowledge and clinical experience of Swiss neurological and neurosurgical communities regarding MRgHiFUS interventions for brain disorders to be published as a national consensus paper.Methods: Eighteen experienced neurosurgeons and neurologists practicing in Switzerland in the field of movement disorders and one health physicist representing 15 departments of 12 Swiss clinical centers and 5 medical societies participated in the workshop and contributed to the consensus paper. All experts have experience with current treatment modalities or with MRgHiFUS. They were invited to participate in two workshops and consensus meetings and one online meeting. As part of workshop preparations, a thorough literature review was undertaken and distributed among participants together with a list of relevant discussion topics. Special emphasis was put on current experience and practice, and areas of controversy regarding clinical application of MRgHiFUS for functional neurosurgery.Results: The recommendations addressed lesioning for treatment of brain disorders in general, and with respect to MRgHiFUS indications, stereotactic targets, treatment alternatives, patient selection and management, standardization of reporting and follow-up, and initialization of a national registry for interventional therapies of movement disorders. Good clinical evidence is presently only available for unilateral thalamic lesioning in treating essential tremor or tremor-dominant Parkinson's disease and, to a minor extent, for unilateral subthalamotomy for Parkinson's disease motor features. However, the workgroup unequivocally recommends further exploration and adaptation of MRgHiFUS-based functional lesioning interventions and confirms the need for outcome-based evaluation of these approaches based on a unified registry. MRgHiFUS and DBS should be evaluated by experts familiar with both methods, as they are mutually complementing therapy options to be appreciated for their distinct advantages and potential.Conclusion: This multidisciplinary consensus paper is a representative current recommendation for safe implementation and standardized practice of MRgHiFUS treatments for functional neurosurgery in Switzerland.

scholarly journals The role of acoustic nonlinearity in tissue heating behind a rib cage using a high-intensity focused ultrasound phased array

2013 ◽  
Vol 58 (8) ◽  
pp. 2537-2559 ◽  
Author(s):  
Petr V Yuldashev ◽  
Svetlana M Shmeleva ◽  
Sergey A Ilyin ◽  
Oleg A Sapozhnikov ◽  
Leonid R Gavrilov ◽  
...  
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
Phased Array ◽  
High Intensity Focused Ultrasound ◽  
Rib Cage ◽  
Acoustic Nonlinearity ◽  
Tissue Heating

scholarly journals Technology-Based Neurorehabilitation in Parkinson’s Disease—A Narrative Review

2021 ◽  
Vol 5 (3) ◽  
pp. 23
Author(s):  
Jens Carsten Möller ◽  
Daniel Zutter ◽  
Robert Riener
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Virtual Reality ◽  
Current Literature ◽  
High Intensity ◽  
Narrative Review ◽  
Efficacy And Safety ◽  
Robot Assisted ◽  
Computer Interfaces

This narrative review provides a brief overview of the current literature on technology-based interventions for the neurorehabilitation of persons with Parkinson’s disease (PD). The role of brain–computer interfaces, exergaming/virtual-reality-based exercises, robot-assisted therapies and wearables is discussed. It is expected that technology-based neurorehabilitation will gain importance in the management of PD patients, although it is often not clear yet whether this approach is superior to conventional therapies. High-intensity technology-based neurorehabilitation may hold promise with respect to neuroprotective or neurorestorative actions in PD. Overall, more research is required in order to obtain more data on the feasibility, efficacy and safety of technology-based neurorehabilitation in persons with PD.

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