Placebo effect in Parkinson's disease: Harnessing the mind in the treatment of PD

2015 ◽  
Vol 30 (6) ◽  
pp. 786-786 ◽  
Author(s):  
Kaviraja Udupa ◽  
Susan H. Fox
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Placebo Effect ◽  
The Mind

Theory of the mind in subjects with Parkinson's disease: A case-control study

2016 ◽  
Vol 22 ◽  
pp. e58
Author(s):  
Genny Giselle Arciniega-Martinez ◽  
Adib Jorge de Sarachaga ◽  
Jackeline Estephanie Simancas-Ruiz ◽  
Marisa Selene Escobar-Barrios ◽  
Elsa Edith Carreon-Bautista ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Case Control Study ◽  
Case Control ◽  
The Mind ◽  
Control Study

scholarly journals MIND diet associated with later onset of Parkinson's disease

2020 ◽  
Author(s):  
Avril Metcalfe-Roach ◽  
Adam Yu ◽  
Ella Golz ◽  
Kristen Sundvick ◽  
Mihai Cirstea ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Mediterranean Diet ◽  
Dietary Habits ◽  
Age Of Onset ◽  
Disease Onset ◽  
Cross Sectional ◽  
Diet Adherence ◽  
The Mind ◽  
Mind Diet

Background: The MIND diet has been linked with prevention of Alzheimer's disease and cognitive decline but has not been fully assessed in the context of Parkinson's disease (PD). Objective: To determine whether MIND diet adherence is associated with the age of Parkinson's disease onset in a manner superior to that of the Mediterranean diet. Methods: Food Frequency Questionnaires from 167 participants with PD and 119 controls were scored for MIND and two versions of Mediterranean diet adherence. Scores were compared between sex and disease subgroups, and PD diet adherence was correlated with age of onset using univariate and multivariate linear models. Results: The female subgroup adhered more closely to the MIND diet than the males, and diet scores were not modified by disease status. Later age of onset correlated most strongly with MIND diet adherence in the female subgroup, corresponding to differences of up to 17.4 years (p<0.001) between low and high dietary tertiles. Greek Mediterranean adherence was also significantly associated with later PD onset across all models (p=0.05-0.03). Conversely, only Greek Mediterranean adherence remained correlated with later onset across all models in men, with differences of up to 8.4 years (p=0.002). Conclusions: This cross-sectional study finds a strong correlation of age of onset of PD with dietary habits, suggesting that nutritional strategies may be an effective tool to delay PD onset. Further studies may help to elucidate potential nutrition-related sex-specific pathophysiological mechanisms and differential prevalence rates in PD.

Diseases of the nervous system

2020 ◽  
pp. 303-332
Author(s):  
Fabrizio Benedetti
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Nervous System ◽  
Placebo Effect ◽  
Neurological Diseases ◽  
Drug Dosage ◽  
Therapeutic Effects ◽  
Verbal Instructions ◽  
System P ◽  
Motor Thalamus

This chapter is dedicated to motor disorders, first and foremost Parkinson’s disease, the area together with pain where most of the knowledge about the mechanisms of the placebo effect comes from. The placebo effect in Parkinson’s disease is mediated by dopamine release in the striatum and is associated with changes in activity of neurons in the subthalamic nucleus, substantia nigra pars reticulata, and motor thalamus. Deceptive verbal instructions about changes in drug dosage can affect the pharmacological effect of levodopa in the treatment of Parkinson’s disease. The therapeutic effects of deep brain stimulation are powerfully modulated by placebos. Migraine is another disease of the nervous system that shows very high rates of improvement in patients who received placebo, although the mechanisms are little understood. Other neurological diseases, like epilepsy, show improvements in placebo groups, but the mechanisms are not known.

The placebo effect in Parkinson's disease

2002 ◽  
Vol 25 (6) ◽  
pp. 302-306 ◽  
Author(s):  
R de la Fuente-Fernández
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Placebo Effect

The Placebo Effect in Parkinson’s Disease

2004 ◽  
Author(s):  
Sarah Lidstone ◽  
A Jon Stoessl ◽  
Raul de la Fuente-Fernandez
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Placebo Effect

Depression and Parkinson's disease: a conceptual challenge

2002 ◽  
Vol 14 (3) ◽  
pp. 147-153 ◽  
Author(s):  
A. F. G. Leentjens ◽  
F. R. J. Verhey
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Relevant Literature ◽  
Point Of View ◽  
Diagnosis And Treatment ◽  
Erroneous Belief ◽  
The Mind

Aim:To explore the relation between Parkinson's disease (PD) and depression from a conceptual point of view.Methods:Discussion of the relevant literature on the conceptual, phenomenological and therapeutical aspects of depression in Parkinson's disease.Results:Both semantic confusion and an erroneous belief in the mind-body distinction have contributed to some common misunderstandings of the nosology and etiology of depression in Parkinson's disease.Conclusion:The consequences of a different, integrated, neuropsychiatric approach for both diagnosis and treatment are discussed.

The placebo effect on resting tremor in Parkinson's disease: an electrophysiological study

2018 ◽  
Vol 52 ◽  
pp. 17-23 ◽  
Author(s):  
Gaetano Barbagallo ◽  
Rita Nisticò ◽  
Basilio Vescio ◽  
Antonio Cerasa ◽  
Giuseppe Olivadese ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Placebo Effect ◽  
Electrophysiological Study ◽  
Resting Tremor
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