Primary sleep disorder prevalence in patients with newly diagnosed Parkinson's disease

2013 ◽  
Vol 29 (2) ◽  
pp. 259-262 ◽  
Author(s):  
Benjamin Prudon ◽  
Gordon W. Duncan ◽  
Tien K. Khoo ◽  
Alison J. Yarnall ◽  
David J. Burn ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Sleep Disorder ◽  
Newly Diagnosed ◽  
Primary Sleep Disorder

scholarly journals Cognitive Function Characteristics of Parkinson’s Disease with Sleep Disorders

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Jing Huang ◽  
Wenyan Zhuo ◽  
Yuhu Zhang ◽  
Hongchun Sun ◽  
Huan Chen ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Function ◽  
Sleep Disorders ◽  
Sleep Disorder ◽  
Control Group ◽  
Different Types ◽  
Healthy Control ◽  
State Examination ◽  
Primary Sleep Disorder

Objective. The aim of this study was to investigate the cognitive function characteristics of Parkinson’s disease (PD) with sleep disorders. Methods. Consecutive patients with PD (n=96), patients with primary sleep disorders (n=76), and healthy control subjects (n=66) were assessed. The patients with PD were classified into sleep disorder (PD-SD) and non-sleep disorder (PD-NSD) groups. Results. Among 96 patients with PD, 69 were diagnosed with a sleep disorder. There were 38 sleep disorder cases, 31 RBD cases, and 27 NSD cases. On the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), and MoCA subtests, patients in the PD-SD, primary sleep disorder, and PD-NSD groups exhibited lower scores than those in the control group. Moreover, the PD-SD patients exhibited more significant cognitive impairment than was observed in the primary sleep disorder patients. In the PD-SD subgroup, the attention scores on the MoCA and on MoCA subtests were lower in the PD with RBD group than in the PD with insomnia group. Conclusion. PD with sleep disorders may exacerbate cognitive dysfunction in patients. PD associated with different types of sleep disorders differentially affects cognitive functions, and patients with PD with RBD exhibited poorer cognitive function than was seen in patients with PD with insomnia.

scholarly journals Characteristics of Parkinson’s Disease in Patients with and without Cognitive Impairment

2021 ◽  
pp. 1-12
Author(s):  
Julie Chandler ◽  
Radhika Nair ◽  
Kevin Biglan ◽  
Erin A. Ferries ◽  
Leanne Munsie ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Emergency Department ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Memory Loss ◽  
Patient Characteristics ◽  
Emergency Department Visits ◽  
Administrative Claims ◽  
Newly Diagnosed ◽  
Comorbidity Burden

Background: Characterizing patients with Parkinson’s disease (PD) and cognitive impairment is important toward understanding their natural history. Objective: Understand clinical, treatment, and cost characteristics of patients with PD pre- and post-cognitive impairment (memory loss/mild cognitive impairment/dementia or dementia treatment) recognition. Methods: 2,711 patients with PD newly diagnosed with cognitive impairment (index) were identified using administrative claims data. They were matched (1:1) on age and gender to patients with PD and no cognitive impairment (controls). These two cohorts were compared on patient characteristics, healthcare resource utilization, and total median costs for 3 years pre- and post-index using Chi-square tests, t-tests, and Wilcoxon rank-sum tests. Logistic regression was used to identify factors predicting cognitive impairment. Results: Comorbidity indices for patients with cognitive impairment increased during the 6-year study period, especially after the index. Enrollment in Medicare Advantage Prescription Drug plans vs. commercial (OR = 1.60), dual Medicare/Medicaid eligibility (OR = 1.36), cerebrovascular disease (OR = 1.24), and PD medication use (OR = 1.46) were associated with a new cognitive impairment diagnosis (all p <  0.05). A greater proportion of patients with cognitive impairment had hospitalizations and emergency department visits and higher median total healthcare costs than controls for each year pre- and post-index. Conclusion: In patients with PD newly diagnosed with cognitive impairment, comorbidity burden, hospitalizations, emergency department visits, and total costs peaked 1-year pre- and post-identification. These data coupled with recommendations for annual screening for cognitive impairment in PD support the early diagnosis and management of cognitive impairment in order to optimize care for patients and their caregivers.

The use of dopamine agonists in newly diagnosed Parkinson's disease patients has changed

2014 ◽  
Vol 5 (5) ◽  
pp. 357-358
Author(s):  
H. Kuusisto ◽  
P. Hujanen ◽  
T. Mattila ◽  
T. Luukkaala ◽  
T. Keränen
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Dopamine Agonists ◽  
Newly Diagnosed

scholarly journals Trend of recognizing depression symptoms and antidepressants use in newly diagnosed Parkinson's disease: Population‐based study

2021 ◽  
Author(s):  
Khalid Orayj ◽  
Tahani Almeleebia ◽  
Easwaran Vigneshwaran ◽  
Sultan Alshahrani ◽  
Sirajudeen. S. Alavudeen ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Population Based ◽  
Depression Symptoms ◽  
Newly Diagnosed ◽  
Population Based Study

The oasis (opicapone in sleep disorder) study in Parkinson's disease: Design and rationale of an open-label, single-arm, pilot trial

2021 ◽  
Vol 429 ◽  
pp. 119430
Author(s):  
Raquel Costa ◽  
Claudia Trenkwalder ◽  
Joaquim Ferreira ◽  
Diogo Magalhães ◽  
José Rocha ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Sleep Disorder ◽  
Pilot Trial ◽  
Open Label

scholarly journals Verbal memory is associated with structural hippocampal changes in newly diagnosed Parkinson's disease

2012 ◽  
Vol 84 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Mona K Beyer ◽  
Kolbjorn S Bronnick ◽  
Kristy S Hwang ◽  
Niels Bergsland ◽  
Ole Bjorn Tysnes ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Verbal Memory ◽  
Newly Diagnosed

scholarly journals Predicting first fall in newly diagnosed Parkinson's disease: Insights from a fall-naïve cohort

2016 ◽  
Vol 31 (12) ◽  
pp. 1829-1836 ◽  
Author(s):  
Sue Lord ◽  
Brook Galna ◽  
Alison J. Yarnall ◽  
Shirley Coleman ◽  
David Burn ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Newly Diagnosed
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