Efficacy and safety of incobotulinumtoxinA (NT 201, Xeomin) in the treatment of blepharospasm-A randomized trial

2011 ◽  
Vol 26 (8) ◽  
pp. 1521-1528 ◽  
Author(s):  
Joseph Jankovic ◽  
Cynthia Comella ◽  
Angelika Hanschmann ◽  
Susanne Grafe
Keyword(s):  
Randomized Trial ◽  
Efficacy And Safety ◽  
Nt 201

Efficacy and safety of Apremilast in Japanese patients with moderate to severe psoriasis: 68-week results from a phase 2b randomized trial

2017 ◽  
Vol 86 (2) ◽  
pp. e8 ◽  
Author(s):  
Mayumi Komine ◽  
Mamitaro Ohtsuki ◽  
Yukari Okubo ◽  
Shinichi Imafuku ◽  
Robert M. Day ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Japanese Patients ◽  
Severe Psoriasis ◽  
Efficacy And Safety

Efficacy and Safety of Sitagliptin in Patients With Type 2 Diabetes and ESRD Receiving Dialysis: A 54-Week Randomized Trial

2013 ◽  
Vol 61 (4) ◽  
pp. 579-587 ◽  
Author(s):  
Juan C. Arjona Ferreira ◽  
Dalila Corry ◽  
Carl E. Mogensen ◽  
Lance Sloan ◽  
Lei Xu ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Randomized Trial ◽  
Efficacy And Safety

Efficacy and safety of etelcalcetide compared with cinacalcet in patients received hemodialysis with secondary hyperparathyroidism. Results from a prospective randomized trial

Nephrology ◽  
2021 ◽  
Vol 2_2021 ◽  
pp. 34-40
Author(s):  
E.V. Shutov Shutov ◽  
G.V. Kotlyarova Kotlyarova ◽  
K.M. Lysenko Lysenko ◽  
G.V. Ryabinskaya Ryabinskaya ◽  
S.V. Lashutin Lashutin ◽  
...  
Keyword(s):  
Secondary Hyperparathyroidism ◽  
Randomized Trial ◽  
Prospective Randomized Trial ◽  
Efficacy And Safety

scholarly journals Efficacy And Safety Of Travoprost Versus Timolol To Treat Early-Onset Ocular Hypertension Secondary To Vitrectomy: A Randomized Trial

2019 ◽  
Vol Volume 13 ◽  
pp. 3453-3463 ◽  
Author(s):  
Yuan Fang ◽  
Hsiangyu Ku ◽  
Dekang Gan ◽  
Rui Jiang ◽  
Xinghuai Sun
Keyword(s):  
Randomized Trial ◽  
Ocular Hypertension ◽  
Early Onset ◽  
Efficacy And Safety

scholarly journals Efficacy and safety of kaolin-based hemostatic pad vs. standard mechanical compression following transradial and transulnar access for elective coronary angiography and PCI: RAUL trial substudy

2019 ◽  
Vol 35 (4) ◽  
pp. 502-508 ◽  
Author(s):  
Lewandowski Pawel ◽  
Gralak-Lachowska Dagmara ◽  
Maciejewski Pawel ◽  
Ramotowski Bogumil ◽  
Budaj Andrzej ◽  
...  
Keyword(s):  
Coronary Angiography ◽  
Randomized Trial ◽  
Artery Occlusion ◽  
Efficacy And Safety ◽  
Mechanical Compression ◽  
Single Center ◽  
Analog Scale ◽  
Transradial Approach ◽  
Patient Pain ◽  
Secondary Endpoints

Abstract Hemostatic devices used in the transradial approach (TRA) and transulnar approach (TUA) are limited. This study compared the efficacy and safety of hemostasis using the QuikClot Radial hemostatic pad (QC) vs. standard mechanical compression (SC) after coronary angiography (CAG). This prospective single-center randomized trial included CAG patients. The primary and secondary endpoints were efficacy (successful hemostasis) and safety (total artery occlusion [TAO], pseudoaneurysm, hematoma), respectively. A visual analog scale (VAS) evaluated patient pain during compression. In 2013–2017, 200 patients were randomized 2 × 2 into the: (1) TRA and TUA groups and (2) QC and SC groups. Successful hemostasis was achieved in 92 (92%) patients in the QC group and 100 (100%) patients in the SC group (p < 0.006). The TRA SC subgroup showed significantly better results than the TRA QC subgroup (100% vs. 90.0%; p < 0.03). Similar results were obtained in the TUA QC and TUA SC subgroups (95% vs. 100%; p = 0.5). The secondary endpoint was achieved in the QC and SC groups (8% vs. 9%; p = 0.8). Patients reported significantly less pain during QC application than during SC (VAS: 2.6 ± 2.6 vs. 3.4 ± 2.9; p < 0.03). In patients undergoing CAG with TRA or TUA, QC was associated with lower efficacy, less discomfort, and similar safety compared to SC.

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