Task force report on scales to assess dyskinesia in Parkinson's disease: Critique and recommendations

2010 ◽  
Vol 25 (9) ◽  
pp. 1131-1142 ◽  
Author(s):  
Carlo Colosimo ◽  
Pablo Martínez-Martín ◽  
Giovanni Fabbrini ◽  
Robert A. Hauser ◽  
Marcelo Merello ◽  
...  
2004 ◽  
Vol 19 (9) ◽  
pp. 1020-1028 ◽  
Author(s):  
Christopher G. Goetz ◽  
Werner Poewe ◽  
Olivier Rascol ◽  
Cristina Sampaio ◽  
Glenn T. Stebbins ◽  
...  

2021 ◽  
pp. 1-9
Author(s):  
Travis H. Turner ◽  
Alexandra Atkins ◽  
Richard S.E. Keefe

Background: Cognitive impairment is common in Parkinson’s disease (PD) and highly associated with loss of independence, caregiver burden, and assisted living placement. The need for cognitive functional capacity tools validated for use in PD clinical and research applications has thus been emphasized in the literature. The Virtual Reality Functional Capacity Assessment Tool (VRFCAT-SL) is a tablet-based instrument that assesses proficiency for performing real world tasks in a highly realistic environment. Objective: The present study explored application of the VRFCAT-SL in clinical assessments of patients with PD. Specifically, we examined associations between VRFCAT-SL performance and measures of cognition, motor severity, and self-reported cognitive functioning. Methods: The VRFCAT-SL was completed by a sample of 29 PD patients seen in clinic for a comprehensive neuropsychological evaluation. Fifteen patients met Movement Disorders Society Task Force criteria for mild cognitive impairment (PD-MCI); no patients were diagnosed with dementia. Non-parametric correlations between VRFCAT-SL performance and standardized neuropsychological tests and clinical measures were examined. Results: VRFCAT-SL performance was moderately associated with global rank on neuropsychological testing and discriminated PD-MCI. Follow-up analyses found completion time was associated with visual memory, sustained attention, and set-switching, while errors were associated with psychomotor inhibition. No clinical or motor measures were associated with VRFCAT-SL performance. Self-report was not associated with VRFCAT-SL or neuropsychological test performance. Conclusion: The VRFCAT-SL appears to provide a useful measure of cognitive functional capacity that is not confounded by PD motor symptoms. Future studies will examine utility in PD dementia.


2011 ◽  
Vol 17 (8) ◽  
pp. 621-624 ◽  
Author(s):  
P. Martinez-Martin ◽  
C. Falup-Pecurariu ◽  
C. Rodriguez-Blazquez ◽  
M. Serrano-Dueñas ◽  
F.J. Carod Artal ◽  
...  

2008 ◽  
Vol 2 (4) ◽  
pp. 261-266
Author(s):  
Jorge Lorenzo Otero

Abstract Dementia with Parkinson's disease represents a controversial issue in the complex group of alpha-synucleinopathies. The author acknowledges the concept of a "continuum" between Parkinson disease's (PD), Lewy body dementia (LBD), and dementia in Parkinson's disease (PDD). However, the practicing neurologist needs to identify the phenotypic signs of each dementia. The treatment and prognosis are different in spite of the overlaps between them. The main aim of this review was to characterize the clinical diagnoses of dementia associated with Parkinson's disease (PDD). Secondarily, the review discussed some epidemiological and neuropsychological issues. Selection of articles was not systematic and reflects the author's opinion, where the main text selected was the recommendations from the Movement Disorder Society Task Force for PDD diagnosis. The Pub Med, OVID, and Proquest data bases were used for the search.


2007 ◽  
Vol 22 (16) ◽  
pp. 2314-2324 ◽  
Author(s):  
Bruno Dubois ◽  
David Burn ◽  
Christopher Goetz ◽  
Dag Aarsland ◽  
Richard G. Brown ◽  
...  

2010 ◽  
Vol 25 (7) ◽  
pp. 805-822 ◽  
Author(s):  
Joseph H. Friedman ◽  
Guido Alves ◽  
Peter Hagell ◽  
Johan Marinus ◽  
Laura Marsh ◽  
...  

2012 ◽  
Vol 24 (12) ◽  
pp. 1980-1987 ◽  
Author(s):  
Wei-Ju Lee ◽  
Chia-Fen Tsai ◽  
Serge Gauthier ◽  
Shuu-Jiun Wang ◽  
Jong-Ling Fuh

ABSTRACTBackground: Neuropsychiatric symptoms (NPS) are common in patients with dementia associated with Parkinson's disease (PDD). The relationship between cognition and NPS in PDD has not been well studied.Methods: Patients diagnosed with PDD were assessed for cognitive function and NPS. The instruments used were the Neuropsychiatric Inventory (NPI), Mini-Mental State Examination (MMSE), and semantic verbal fluency according to the recommendation of the Movement Disorder Society Task Force.Results: We evaluated 127 PDD patients (76 males/51 females; mean age 77 ± 6.3 years). Their mean MMSE score was 17 ± 6.5 and the mean NPI score was 19 ± 20.4. The most prevalent NPI items were anxiety (57.5%), sleep problems (53.5%), and apathy (52.0%). Principal component factor analysis revealed that 12 items formed three factors, namely “mood and psychosis” (delusion, hallucination, agitation, depression, anxiety, apathy, and irritability), “vegetative” (sleep and appetite problems), and “frontal” (euphoria, disinhibition, and aberrant motor behavior). Symptoms of hallucination were significantly associated with MMSE score, even after controlling for the confounding variables.Conclusion: NPS are common and diverse among patients with PDD. Three specific subgroups of NPS were identified. Hallucination was significantly correlated with cognitive impairment, and could be a predictor of cognition in PDD patients.


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