Reply: Neuropathy as a potential complication of levodopa use in Parkinson's disease: A pharmacological and pharmacovigilance point of view

2010 ◽  
Vol 25 (4) ◽  
pp. 525-525 ◽  
Author(s):  
Cory Toth ◽  
Oksana Suchowersky ◽  
Douglas Zochodne
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Point Of View ◽  
Potential Complication

Neuropathy as a potential complication of levodopa use in Parkinson's disease: A Pharmacological and Pharmacovigilance point of view

2010 ◽  
Vol 25 (5) ◽  
pp. 660-661 ◽  
Author(s):  
Jean-Louis Montastruc ◽  
Anne Charlotte Danton ◽  
Genevieve Durrieu ◽  
Isabelle Lacroix ◽  
Pascale Olivier ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Point Of View ◽  
Potential Complication

Neuropathy as a potential complication of levodopa use in Parkinson's disease

2008 ◽  
Vol 23 (13) ◽  
pp. 1850-1859 ◽  
Author(s):  
Cory Toth ◽  
Martin Sutton Brown ◽  
Sarah Furtado ◽  
Oksana Suchowersky ◽  
Douglas Zochodne
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Potential Complication

scholarly journals Stigma Experienced by Parkinson’s Disease Patients: A Descriptive Review of Qualitative Studies

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Marina Maffoni ◽  
Anna Giardini ◽  
Antonia Pierobon ◽  
Davide Ferrazzoli ◽  
Giuseppe Frazzitta
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Literature Review ◽  
Subjective Experience ◽  
Negative Impact ◽  
Social Stigma ◽  
Subjective Symptom ◽  
Point Of View ◽  
Pubmed Database ◽  
Related Quality

Parkinson’s disease (PD) is a neurodegenerative disease characterized by motor and nonmotor symptoms. Both of them imply a negative impact on Health-Related Quality of Life. A significant one is the stigma experienced by the parkinsonian patients and their caregivers. Moreover, stigma may affect everyday life and patient’s subjective and relational perception and it may lead to frustration and isolation. Aim of the present work is to qualitatively describe the stigma of PD patients stemming from literature review, in order to catch the subjective experience and the meaning of the stigma construct. Literature review was performed on PubMed database and Google Scholar (keywords: Parkinson Disease, qualitative, stigma, social problem, isolation, discrimination) and was restricted to qualitative data: 14 articles were identified to be suitable to the aim of the present overview. Results are divided into four core constructs: stigma arising from symptoms, stigma linked to relational and communication problems, social stigma arising from sharing perceptions, and caregiver’s stigma. The principal relations to these constructs are deeply analyzed and described subjectively through patients’ and caregiver’s point of view. The qualitative research may allow a better understanding of a subjective symptom such as stigma in parkinsonian patients from an intercultural and a social point of view.

scholarly journals Towards understanding neural network signatures of motor skill learning in Parkinson’s disease and healthy aging

2019 ◽  
Vol 92 (1101) ◽  
pp. 20190071 ◽  
Author(s):  
Evelien Nackaerts ◽  
Nicholas D'Cruz ◽  
Bauke W Dijkstra ◽  
Moran Gilat ◽  
Thomas Kramer ◽  
...  
Keyword(s):  
Neural Network ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Learning ◽  
Healthy Aging ◽  
Network Connectivity ◽  
Cognitive Networks ◽  
Skill Learning ◽  
Point Of View ◽  
Detailed Knowledge

In the past decade, neurorehabilitation has been shown to be an effective therapeutic supplement for patients with Parkinson’s disease (PD). However, patients still experience severe problems with the consolidation of learned motor skills. Knowledge on the neural correlates underlying this process is thus essential to optimize rehabilitation for PD. This review investigates the existing studies on neural network connectivity changes in relation to motor learning in healthy aging and PD and critically evaluates the imaging methods used from a methodological point of view. The results indicate that despite neurodegeneration there is still potential to modify connectivity within and between motor and cognitive networks in response to motor training, although these alterations largely bypass the most affected regions in PD. However, so far training-related changes are inferred and possible relationships are not substantiated by brain–behavior correlations. Furthermore, the studies included suffer from many methodological drawbacks. This review also highlights the potential for using neural network measures as predictors for the response to rehabilitation, mainly based on work in young healthy adults. We speculate that future approaches, including graph theory and multimodal neuroimaging, may be more sensitive than brain activation patterns and model-based connectivity maps to capture the effects of motor learning. Overall, this review suggests that methodological developments in neuroimaging will eventually provide more detailed knowledge on how neural networks are modified by training, thereby paving the way for optimized neurorehabilitation for patients.

scholarly journals Anti-Oxidants in Parkinson's Disease Therapy: A Critical Point of View

2016 ◽  
Vol 14 (3) ◽  
pp. 260-271 ◽  
Author(s):  
Roberta Filograna ◽  
Mariano Beltramini ◽  
Luigi Bubacco ◽  
Marco Bisaglia
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Critical Point ◽  
Point Of View ◽  
Disease Therapy

Depression and Parkinson's disease: a conceptual challenge

2002 ◽  
Vol 14 (3) ◽  
pp. 147-153 ◽  
Author(s):  
A. F. G. Leentjens ◽  
F. R. J. Verhey
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Relevant Literature ◽  
Point Of View ◽  
Diagnosis And Treatment ◽  
Erroneous Belief ◽  
The Mind

Aim:To explore the relation between Parkinson's disease (PD) and depression from a conceptual point of view.Methods:Discussion of the relevant literature on the conceptual, phenomenological and therapeutical aspects of depression in Parkinson's disease.Results:Both semantic confusion and an erroneous belief in the mind-body distinction have contributed to some common misunderstandings of the nosology and etiology of depression in Parkinson's disease.Conclusion:The consequences of a different, integrated, neuropsychiatric approach for both diagnosis and treatment are discussed.

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