Substantia nigra echogenicity: A structural correlate of functional impairment of the dopaminergic striatal projection in Parkinson's disease

2009 ◽  
Vol 24 (11) ◽  
pp. 1669-1675 ◽  
Author(s):  
David Weise ◽  
Reinhard Lorenz ◽  
Mira Schliesser ◽  
Andreas Schirbel ◽  
Karlheinz Reiners ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Substantia Nigra ◽  
Functional Impairment ◽  
Structural Correlate ◽  
Substantia Nigra Echogenicity

Substantia nigra echogenicity in Parkinson’s disease: relation to serum iron and C-reactive protein

2011 ◽  
Vol 119 (1) ◽  
pp. 53-57 ◽  
Author(s):  
Uwe Walter ◽  
Rike Witt ◽  
Alexander Wolters ◽  
Matthias Wittstock ◽  
Reiner Benecke
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Substantia Nigra ◽  
Serum Iron ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Substantia Nigra Echogenicity

Substantia nigra echogenicity and imaging of striatal dopamine transporters in Parkinson's disease: A cross-sectional study

2014 ◽  
Vol 20 (5) ◽  
pp. 477-481 ◽  
Author(s):  
Edson Bor-Seng-Shu ◽  
Jose Luiz Pedroso ◽  
Andre C. Felicio ◽  
Daniel Ciampi de Andrade ◽  
Manoel Jacobsen Teixeira ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Substantia Nigra ◽  
Cross Sectional Study ◽  
Striatal Dopamine ◽  
Sectional Study ◽  
Dopamine Transporters ◽  
Cross Sectional ◽  
Substantia Nigra Echogenicity

Substantia nigra echogenicity correlated with clinical features of Parkinson's disease

2016 ◽  
Vol 24 ◽  
pp. 28-33 ◽  
Author(s):  
Hai-Yan Zhou ◽  
Qian Sun ◽  
Yu-Yan Tan ◽  
Yun-Yun Hu ◽  
Wei-Wei Zhan ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Substantia Nigra ◽  
Clinical Features ◽  
Substantia Nigra Echogenicity

Substantia Nigra Echogenicity Associated with Clinical Subtypes of Parkinson’s Disease

2018 ◽  
Vol 8 (2) ◽  
pp. 333-340 ◽  
Author(s):  
Hai-Yan Zhou ◽  
Pei Huang ◽  
Qian Sun ◽  
Juan-Juan Du ◽  
Shi-Shuang Cui ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Substantia Nigra ◽  
Substantia Nigra Echogenicity

scholarly journals Measurement of the adult human midbrain with transcranial ultrasound

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0247920
Author(s):  
Karl Aoun ◽  
Kay L. Double ◽  
Verity Pearson-Dennett ◽  
Rezzak Yilmaz ◽  
Daniela Berg ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Substantia Nigra ◽  
Cross Sectional Area ◽  
Control Group ◽  
Sectional Area ◽  
Cross Sectional ◽  
Methamphetamine Use ◽  
History Of ◽  
Substantia Nigra Echogenicity

Background Transcranial sonography is increasingly used to aid clinical diagnoses of movement disorders, for example, to identify an enlarged area of substantia nigra echogenicity in patients with Parkinson’s disease. Objective The current study investigated characteristics of the midbrain at the anatomical plane for quantification of substantia nigra echogenicity. METHODS: Area of substantia nigra echogenicity, cross-sectional area of the midbrain, and interpeduncular angle were quantified in two groups of adults aged 18–50 years: 47 healthy non-drug-using controls (control group) and 22 individuals with a history of methamphetamine use (methamphetamine group), a cohort with a high prevalence of enlarged substantia nigra echogenicity and thus risk of Parkinson’s disease. Results In the control group, cross-sectional area of the midbrain (4.47±0.44 cm2) and interpeduncular angle were unaffected by age, sex, or image acquisition side. In the methamphetamine group, cross-sectional midbrain area (4.72±0.60 cm2) and area of substantia nigra echogenicity were enlarged compared to the control group, and the enlargement was sex-dependent (larger in males than females). Whole midbrain area and interpeduncular angle were found to be weak predictors of area of substantia nigra echogenicity after accounting for group and sex. Conclusions History of methamphetamine use is associated with an enlarged midbrain and area of substantia nigra echogenicity, and the abnormality is more pronounced in males than females. Thus, males may be more susceptible to methamphetamine-induced changes to the brainstem, and risk of Parkinson’s disease, than females.

Does normal substantia nigra echogenicity make a difference in Parkinson’s disease diagnosis? A real clinical practice follow-up study

2018 ◽  
Vol 265 (10) ◽  
pp. 2363-2369
Author(s):  
Araceli Alonso-Canovas ◽  
Jose Luis Lopez-Sendon Moreno ◽  
Javier Buisan ◽  
Susana Sainz de la Maza ◽  
Lucienne Costa-Frossard ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Practice ◽  
Substantia Nigra ◽  
Disease Diagnosis ◽  
Follow Up Study ◽  
Substantia Nigra Echogenicity ◽  
Real Clinical Practice
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