Pisa syndrome without neuroleptic exposure in a patient with Parkinson's disease: Case report

2006 ◽  
Vol 21 (2) ◽  
pp. 270-273 ◽  
Author(s):  
Mattia Gambarin ◽  
Angelo Antonini ◽  
Giuseppe Moretto ◽  
Paolo Bovi ◽  
Silvia Romito ◽  
...  
2009 ◽  
Vol 285 ◽  
pp. S122-S123
Author(s):  
H. Apaydin ◽  
S. Ozekmekci ◽  
D. Uluduz ◽  
Y. Hatano ◽  
Y. Mizuno ◽  
...  

2004 ◽  
Vol 25 (7) ◽  
pp. 548-549 ◽  
Author(s):  
Ece Aydoğ ◽  
Emel Ekşioğlu ◽  
Aytül Çakci ◽  
Özge Yilmaz

2011 ◽  
Vol 26 (S2) ◽  
pp. 846-846
Author(s):  
S.G. Oliveira ◽  
S.M. Pereira ◽  
J. Mendes

IntroductionParkinson's disease (PD) dementia is a rapidly growing global health problem. Dementia in PD is often accompanied with neuropsychiatric manifestations, such as depression, insomnia, visual hallucinations and psychomotor agitation, which need psychiatric attention.ObjectivesThe authors’ aim is to report a case of a 76-year-old female suffering from PD who was admitted to the psychiatric yard exhibiting neuropsychiatric symptoms. A literature's review about PD dementia was also made.Case reportPatient had one psychiatric hospitalization at age 41, due to depressive symptoms. PD diagnose was made at age 65 and initially responded well to levodopa. Over the subsequent years, motor fluctuations and dyskinesias as well as autonomic, cognitive and psychological symptoms gradually developed. At 75 years, patient's family stated that she had been more forgetful, impulsive, showing signs of anxiety and dysphoria. She was hospitalized exhibiting psychomotor agitation, disorientation, insomnia and mainly nocturnal visual hallucinations with persons. Diagnostic testing included: cranial tomography which showed mild generalized atrophy but no other structural cause of her symptoms; laboratory tests with B12, folic acid, thyroid function; syphilis detection test and examinations of serum and urine were normal. The MMSE scored 19. Attention deficits and constructional apraxia were present in clock drawing test. Treatment was initiated with memantine and a low dose of quetiapine. She was discharged after 20 days with improvement of neuropsychiatric symptoms.ConclusionsEarly diagnosis and treatment of dementia in PD may prevent psychiatric hospitalization and avoid patient's and family's distress.


2000 ◽  
Vol 58 (3A) ◽  
pp. 724-725 ◽  
Author(s):  
HÉLIO A. G. TEIVE ◽  
DANIEL S. SÁ

We describe a patient whose initial manifestation of Parkinson's disease was a malfunctioning of a self-winding wristwatch secondary to bradykinesia of his left arm. Andrade and Ferraz reported this sign in 1996, suggesting that it be called the Rolex sign.


2008 ◽  
Vol 8 (12) ◽  
pp. 1799-1805 ◽  
Author(s):  
Bradley J Robottom ◽  
Roger J Mullins ◽  
Lisa M Shulman

2021 ◽  
Author(s):  
Renato Serquiz Elias Pinheiro ◽  
Emanuelly da Costa Nobre Soares ◽  
Maria Eduarda Bezerra Figueiredo ◽  
Stella Mandu Cicco

Context: Pisa Syndrome (PS) is a rare postural disorder, characterized by dystonia of the trunk muscles, lateral deviation as well as rotation of the axial axis. There is a strong association with Parkinson’s disease (PD) due to the possible imbalance between neurotransmitters. It happens either due to a decrease in dopaminergic stimuli, either because of an excess of cholinergic stimuli or drugs (an example of antidopaminergics). The diagnosis is clinical, showing at least a 10-degree trunk flexion with improvement of pharmacological and non- pharmacological measures. Case report: A 60-year-old man was diagnosed with PD five years ago due to tipical clinical complaints and physical examination. The treatment recquired an increase of Pramipexole as well as the use of Levodopa and Benserazide. After two years, he complained about neck pain, low back pain, hip pain and a slight trunk twisting. After six months, his pain was worse and he reported right hemidystonia. Thus, he was diagnosed with PS associated with PD. It was decided to optimize the therapy with Pregabalin, muscle relaxants and rehabilitation. However, it did not show any good result. In 2020, the application of botulinum toxin (BTX) evidenced excellent results, improving both the pain and the spasticity of the patient. Conclusions: Early recognition is necessary to introduce the right treatment as soon as possible, especially BTX and rehabilitation, ensuring functionality and avoiding negative outcomes.


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