Tremor induced by thalamic deep brain stimulation in patients with complex regional facial pain

2004 ◽  
Vol 19 (8) ◽  
pp. 933-936 ◽  
Author(s):  
Constantine Constantoyannis ◽  
Ajit Kumar ◽  
A. Jon Stoessl ◽  
Christopher R. Honey
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Facial Pain ◽  
Deep Brain

Deep Brain Stimulation for Facial Pain

2020 ◽  
pp. 1-21
Author(s):  
William G.B. Singleton ◽  
Reiko Ashida ◽  
Nikunj K. Patel
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Facial Pain ◽  
Deep Brain

scholarly journals Deep brain stimulation for intractable neuropathic facial pain

2018 ◽  
Vol 45 (2) ◽  
pp. E15 ◽  
Author(s):  
Sharona Ben-Haim ◽  
Zaman Mirzadeh ◽  
William S. Rosenberg
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Facial Pain ◽  
Short Form ◽  
Therapeutic Option ◽  
Mcgill Pain Questionnaire ◽  
Pain Disability Index ◽  
Pain Outcomes ◽  
Maximum Improvement ◽  
Deep Brain

OBJECTIVEDeep brain stimulation (DBS) is a well-established, evidence-based therapy with FDA approval for Parkinson’s disease and essential tremor. Despite the early successful use of DBS to target the sensory thalamus for intractable facial pain, subsequent studies pursuing various chronic pain syndromes reported variable efficacy, keeping DBS for pain as an investigational and “off-label” use. The authors report promising results for a contemporary series of patients with intractable facial pain who were treated with DBS.METHODSPain outcomes for 7 consecutive patients with unilateral, intractable facial pain undergoing DBS of the ventral posteromedial nucleus of the thalamus (VPM) and the periaqueductal gray (PAG) were retrospectively reviewed. Pain was assessed preoperatively and at multiple postoperative time points using the visual analog scale (VAS), the Short-Form McGill Pain Questionnaire-2 (SF-MPQ-2), and the Pain Disability Index (PDI).RESULTSVAS scores significantly decreased from a mean ± SD of 9.0 ± 1.3 preoperatively to 2.6 ± 1.5 at 1 year postoperatively (p = 0.001). PDI scores decreased from a mean total of 48.5 to 28.5 (p = 0.01). SF-MPQ-2 scores decreased from a mean of 4.6 to 2.4 (p = 0.03). Notably, several patients did not experience maximum improvement until 6–9 months postoperatively, correlating with repeated programming adjustments.CONCLUSIONSDBS of the VPM and PAG is a potential therapeutic option for patients suffering from severe, intractable facial pain refractory to other interventions. Improved efficacy may be observed over time with close follow-up and active DBS programming adjustments.

Case Series: Deep Brain Stimulation for Facial Pain

2020 ◽  
Vol 19 (5) ◽  
pp. 510-517
Author(s):  
Alon Kashanian ◽  
Jasmine A T DiCesare ◽  
Pratik Rohatgi ◽  
Luigi Albano ◽  
Scott E Krahl ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Facial Pain ◽  
Case Series ◽  
Atypical Facial Pain ◽  
Average Decrease ◽  
Pain Scores ◽  
Post Traumatic ◽  
Removal Of Hardware ◽  
Deep Brain

Abstract BACKGROUND Deep brain stimulation (DBS) has been used for chronic pain for decades, but its use is limited due to a lack of reliable data about its efficacy for specific indications. OBJECTIVE To report on 9 patients who underwent DBS for facial pain, with a focus on differences in outcomes between distinct etiologies. METHODS We retrospectively reviewed 9 patients with facial pain who were treated with DBS of the ventral posteromedial nucleus of the thalamus and periventricular gray. We report on characteristics including facial pain etiology, complications, changes in pain scores using the visual analog scale (VAS), and willingness to undergo DBS again. RESULTS Nine patients underwent DBS for either poststroke, post-traumatic, postherpetic, or atypical facial pain. Eight patients (89%) were permanently implanted. Seven patients had sufficient follow-up (mean 40.3 mo). Of these 7 patients, average VAS scores decreased from 9.4 to 6.1 after DBS. The average decrease in VAS was 55% for post-traumatic facial pain (2 patients), 45% for poststroke (2 patients), 15% for postherpetic neuralgia (2 patients), and 0% for atypical facial pain (1 patient). Three of the 8 implanted patients (38%) had complications which required removal of hardware. Only 2 of 7 (29%) patients met classical criteria for responders (50% decrease in pain scores). However, among 4 patients who were asked about willingness to undergo DBS again, all expressed that they would repeat the procedure. CONCLUSION There is a trend towards improvement in pain scores following DBS for facial pain, most prominently with post-traumatic pain.

Nicht-medikamentöse Optionen zur Behandlung pharmakoresistenter Epilepsien

2018 ◽  
Vol 75 (7) ◽  
pp. 448-454
Author(s):  
Thomas Grunwald ◽  
Judith Kröll
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Tiefe Hirnstimulation ◽  
Ketogene Diät ◽  
Deep Brain

Zusammenfassung. Wenn mit den ersten beiden anfallspräventiven Medikamenten keine Anfallsfreiheit erzielt werden konnte, so ist die Wahrscheinlichkeit, dies mit anderen Medikamenten zu erreichen, nur noch ca. 10 %. Es sollte dann geprüft werden, warum eine Pharmakoresistenz besteht und ob ein epilepsiechirurgischer Eingriff zur Anfallsfreiheit führen kann. Ist eine solche Operation nicht möglich, so können palliative Verfahren wie die Vagus-Nerv-Stimulation (VNS) und die tiefe Hirnstimulation (Deep Brain Stimulation) in eine bessere Anfallskontrolle ermöglichen. Insbesondere bei schweren kindlichen Epilepsien stellt auch die ketogene Diät eine zu erwägende Option dar.

The Effect of Deep Brain Stimulation for Movement Disorders on Emotions

2008 ◽  
Author(s):  
Jonathan D. Richards ◽  
Paul M. Wilson ◽  
Pennie S. Seibert ◽  
Carin M. Patterson ◽  
Caitlin C. Otto ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Movement Disorders ◽  
Deep Brain
Sign in / Sign up

Export Citation Format

Share Document