Development and testing of the Parkinson's disease quality of life scale

2003 ◽  
Vol 18 (6) ◽  
pp. 637-645 ◽  
Author(s):  
Mickie Welsh ◽  
Michael P. McDermott ◽  
Robert G. Holloway ◽  
Sandy Plumb ◽  
Ronald Pfeiffer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Quality Of Life Scale ◽  
Life Scale

scholarly journals Motor Cortex Stimulation in Parkinson's Disease

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Marisa De Rose ◽  
Giusy Guzzi ◽  
Domenico Bosco ◽  
Mary Romano ◽  
Serena Marianna Lavano ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Cortex ◽  
Motor Cortex Stimulation ◽  
Plate Electrode ◽  
Quality Of Life Scale ◽  
Life Scale ◽  
Axial Symptoms

Motor Cortex Stimulation (MCS) is less efficacious than Deep Brain Stimulation (DBS) in Parkinson's disease. However, it might be proposed to patients excluded from DBS or unresponsive to DBS. Ten patients with advanced PD underwent unilateral MCS contralaterally to the worst clinical side. A plate electrode was positioned over the motor cortex in the epidural space through single burr hole after identification of the area with neuronavigation and neurophysiological tests. Clinical assessment was performed by total UPDRS, UPDRS III total, UPDRS III-items 27–31, UPDRS IV, and UPDRS II before implantation in off-medication and on-medication states and after surgery at 1, 3, 6, 12, 18, 24, and 36 months in on-medication/on-stimulation and off-medication/on-stimulation states. We assessed changes of quality of life, throughout the Parkinson's disease quality of life scale (PDQoL-39), and the dose of anti-Parkinson's disease medications, throughout the Ldopa equivalent daily dose (LEDD). During off-medication state, we observed moderate and transitory reduction of total UPDRS and UPDRS total scores and significant and long-lasting improvement in UPDRS III items 27–31 score for axial symptoms. There was marked reduction of UPDRS IV score and LEDD. PDQL-39 improvement was also significant. No important complications and adverse events occurred.

scholarly journals Quality of life scale in parkinson's disease PDQ-39 - (Brazilian Portuguese version) to assess patients with and without levodopa motor fluctuation

2007 ◽  
Vol 65 (3b) ◽  
pp. 787-791 ◽  
Author(s):  
Renata Guzzo Souza ◽  
Vanderci Borges ◽  
Sonia Maria Cesar de Azevedo Silva ◽  
Henrique Ballalai Ferraz
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Fluctuation ◽  
Brazilian Portuguese ◽  
Motor Fluctuations ◽  
Portuguese Version ◽  
Quality Of Life Scale ◽  
Life Scale

Quality of life (QoL) is an important treatment outcome indicator in Parkinson's disease (PD). The aim of this study is to assess the usefulness of the Parkinson's disease questionnaire - PDQ-39 (Brazilian Portuguese Version) in measuring QoL of PD patients with or without motor fluctuations. Fifty-six PD patients with mean disease duration of 7.4 years were assessed and 41 of them (73.3%) had motor fluctuations. The PDQ-39 has eight dimensions ranging from 0 to 100; being the higher the score, the worse the QoL. Comparing groups with and without motor fluctuations showed that the dimensions mobility, activities of daily living (ADL), communication and bodily discomfort scored higher in the fluctuating group. There was a tendency to see that the higher the Hoehn and Yahr (HY) scale stages, the higher the PDQ-39 scores. Patients suffering from the disease for more than five years had worse PDQ-39 scores only in the items ADL and communication, when compared with those with the disease for < 5 years. The PDQ-39 is an instrument that detects decrease in QoL of PD patients and the presence of motor fluctuations predicts QoL reduction.

scholarly journals Relationship between electrode position of deep brain stimulation and motor symptoms of Parkinson’s disease

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Feng Zhang ◽  
Feng Wang ◽  
Weiguo Li ◽  
Ning Wang ◽  
Chunlei Han ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Electrode Position ◽  
Motor Symptoms ◽  
Improvement Rate ◽  
Significant Difference ◽  
Quality Of Life Scale ◽  
Stn Dbs

Abstract Background To investigate the relationship between the position of bilateral STN-DBS location of active contacts and the clinical efficacy of STN-DBS on motor symptoms in Parkinson’s disease (PD) patients. Methods Retrospectively analyze the clinical data of 57 patients with PD who underwent bilateral STN-DBS from March 2018 to December 2018. Unified Parkinson’s Disease Rating Scale-Part III (UPDRS-III) score, levodopa equivalent day dose (LEDD), Parkinson’s Disease Quality of Life Scale (PDQ-39) before operation and within 6 months after operation, determine the location of activated contacts and volume of tissue activated (VTA) in the Montreal Neurological Institute (MNI) space, and analyze their correlation with the improvement rate of motor symptoms (UPDRS-III score improvement rate). Results After 6 months of follow up, the UPDRS-III scores of 57 patients (Med-off) were improved by 55.4 ± 18.9% (P<0.001) compared with that before operation. The improvement rate of PDQ-39 scores [(47.4 ± 23.2)%, (P < 0.001)] and the reduction rate of LEDD [(40.1 ± 24.3)%, (P < 0.01)] at 6 months postoperation were positively correlated with the improvement rate of motor symptoms (Med-off)(PDQ-39:r = 0.461, P<0.001; LEDD: r = 0.354, P = 0.007), the improvement rate of UPDRS-III (Med-off) and the Z-axis coordinate of the active contact in the MNI space were positively correlated (left side: r = 0.349,P = 0.008;right side: r = 0.369,P = 0.005). In the MNI space, there was no correlation between the UPDRS-III scores improvement rate (Med-off) at 6 months after operation and bilateral VTA in the STN motor subregion, STN associative subregion and STN limbic subregion of the active electrode contacts of 57 patients (all P > 0.05). At 6 months after surgery, the difference between the Z-axis coordinate in the different improvement rate subgroups(<25, 25 to 50%, and>50%) in the MNI space was statistically significant (left side: P = 0.030; right side: P = 0.024). In the MNI space, there was no statistically significant difference between the groups in the VTA of the electrode active contacts (all P > 0.05). Conclusion STN-DBS can improve the motor symptoms of PD patients and improve the quality of life. The closer the stimulation is to the STN dorsolateral sensorimotor area, the higher the DBS is to improve the motor symptoms of PD patients.

Stroke Specific Quality of Life Scale--French Version

2018 ◽  
Author(s):  
Nicolas Legris ◽  
Hervé Devilliers ◽  
Anaïs Daumas ◽  
Didier Carnet ◽  
Jean-Pierre Charpy ◽  
...  
Keyword(s):  
Quality Of Life ◽  
French Version ◽  
Quality Of Life Scale ◽  
Life Scale

Acne Quality of Life Scale

1998 ◽  
Author(s):  
Madhulika A. Gupta ◽  
Andrew M. Johnson ◽  
Aditya K. Gupta
Keyword(s):  
Quality Of Life ◽  
Quality Of Life Scale ◽  
Life Scale

Progressive Supranuclear Palsy Quality of Life Scale

2006 ◽  
Author(s):  
A. Schrag ◽  
C. Selai ◽  
N. Quinn ◽  
A. Lees ◽  
I. Litvan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Progressive Supranuclear Palsy ◽  
Quality Of Life Scale ◽  
Life Scale

Acquired Brain Injury Quality of Life Scale

2019 ◽  
Author(s):  
María Fernández ◽  
Laura E. Gómez ◽  
Víctor B. Arias ◽  
Virginia Aguayo ◽  
Antonio M. Amor ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Brain Injury ◽  
Acquired Brain Injury ◽  
Quality Of Life Scale ◽  
Life Scale
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