Motor response to levodopa and the evolution of motor fluctuations in the first decade of treatment of Parkinson's disease

2002 ◽  
Vol 17 (6) ◽  
pp. 1227-1234 ◽  
Author(s):  
Craig D. McColl ◽  
Katrina A. Reardon ◽  
Mark Shiff ◽  
Peter A. Kempster
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Response ◽  
Motor Fluctuations

scholarly journals Limb and trunk accelerometer data collected with wearable sensors from subjects with Parkinson’s disease

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Gloria Vergara-Diaz ◽  
Jean-Francois Daneault ◽  
Federico Parisi ◽  
Chen Admati ◽  
Christina Alfonso ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Symptom Severity ◽  
Wearable Sensors ◽  
Motor Fluctuations ◽  
Sensor Data ◽  
Accelerometer Data ◽  
Motor Tasks ◽  
Specific Symptom ◽  
At Home

AbstractParkinson’s disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms. Dyskinesia and motor fluctuations are complications of PD medications. An objective measure of on/off time with/without dyskinesia has been sought for some time because it would facilitate the titration of medications. The objective of the dataset herein presented is to assess if wearable sensor data can be used to generate accurate estimates of limb-specific symptom severity. Nineteen subjects with PD experiencing motor fluctuations were asked to wear a total of five wearable sensors on both forearms and shanks, as well as on the lower back. Accelerometer data was collected for four days, including two laboratory visits lasting 3 to 4 hours each while the remainder of the time was spent at home and in the community. During the laboratory visits, subjects performed a battery of motor tasks while clinicians rated limb-specific symptom severity. At home, subjects were instructed to use a smartphone app that guided the periodic performance of a set of motor tasks.

Gait analysis in patients with Parkinson's disease and motor fluctuations: Influence of levodopa and comparison with other measures of motor function

1998 ◽  
Vol 13 (6) ◽  
pp. 900-906 ◽  
Author(s):  
John D. O'Sullivan ◽  
Catherine M. Said ◽  
Louise C. Dillon ◽  
Marion Hoffman ◽  
Andrew J. Hughes
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Gait Analysis ◽  
Motor Function ◽  
Motor Fluctuations

Efficacy of opicapone in different treatment regimens in Parkinson's disease patients with motor fluctuations

2020 ◽  
Vol 79 ◽  
pp. e64-e65
Author(s):  
A. Antonini ◽  
G. Ebersbach ◽  
O. Rascol ◽  
F. Ikedo ◽  
D. Magalhães ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Fluctuations ◽  
Treatment Regimens
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