scholarly journals Factors Associated with Low Body Mass Index in Huntington's Disease: A Spanish Multicenter Study of the European Huntington's Disease Registry

2016 ◽  
Vol 3 (5) ◽  
pp. 452-459
Author(s):  
Esther Cubo ◽  
Jessica Rivadeneyra ◽  
Natividad Mariscal ◽  
Asunción Martinez ◽  
Diana Armesto ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Body Mass ◽  
Multicenter Study ◽  
Disease Registry ◽  
Factors Associated ◽  
Low Body Mass Index

Sex-Associated Differences in the Handgrip Strength of Elderly Individuals

2019 ◽  
Vol 42 (4) ◽  
pp. 262-268 ◽  
Author(s):  
Yeunhee Kwak ◽  
Yoonjung Kim ◽  
Haekyung Chung
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Handgrip Strength ◽  
Low Frequency ◽  
Advanced Age ◽  
Related Factors ◽  
Elderly Individuals ◽  
Muscle Strengthening ◽  
Factors Associated ◽  
Low Body Mass Index

This study aimed to identify sex-specific factors associated with handgrip strength in elderly individuals. The analysis cohort comprised 1,197 men and 1,384 women aged ≥65 years. In men, factors associated with low handgrip strength included advanced age; low body mass index; low frequency of performing flexibility exercises; limited self-care ability (which is a measure of the health-related quality of life); and the presence of diabetes, stroke, or osteoporosis ( R² = 0.285, F = 7.52, p < .001). In women, the factors included advanced age, low body mass index, low frequency of performing muscle strengthening exercises, stress, and osteoarthritis ( R² = 0.225, F = 4.17, p < .001). Effective health-promoting interventions for elderly individuals require the development of individualized programs that enhance handgrip strength while considering sex-related factors.

scholarly journals Developmental Trajectory of Height, Weight, and BMI in Children and Adolescents at Risk for Huntington’s Disease: Effect of mHTT on Growth

2020 ◽  
Vol 9 (3) ◽  
pp. 245-251
Author(s):  
Alexander Tereshchenko ◽  
Ellen van der Plas ◽  
Katherine D. Mathews ◽  
Eric Epping ◽  
Amy L. Conrad ◽  
...  
Keyword(s):  
Body Mass Index ◽  
At Risk ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Body Mass ◽  
Child And Adolescent ◽  
Linear Increase ◽  
Developmental Trajectory ◽  
Mutant Form ◽  
The Impact

Background: The gene (Huntingtin or HTT) causing Huntington’s disease (HD) is vital for development and is expressed throughout the brain and body lifelong. The mutant form (mHTT) may influence growth and development. Objective: To determine the impact of mHTT on human measures of growth, including height, weight, and body mass index (BMI), between child and adolescent carriers of mHTT and control peers. Methods: Children ages 6–18 years of age (n = 186) at risk for HD were enrolled in the KidsHD study. For research purposes only, genetic testing was performed to classify participants as Gene-Expanded (GE = 78) or as Gene Non-Expanded (GNE = 108). Outcome measures included height, weight, and body mass index (BMI). Mixed models were used to determine if non-linear age trends differed between groups for BMI, height, and weight. Results: Differences were seen in the trajectory of BMI in which the GE group reached a plateau in late adolescence with no further increase, compared with a nearly linear increase in the GNE group. There was a significant sex interaction pattern where GE males were taller than GNE males in adolescence, in the presence of similar weight. In contrast, GE females weighed significantly less than their GNE counterparts in adolescence, in the presence of similar height. Conclusion: Measures of growth are abnormal in child and adolescent carriers of mHTT, decades before HD onset. Although further studies are needed for replication, the current findings suggest that developmental aberrations may be systemic and a vital part of disease pathology.

scholarly journals Abnormal Weight and Body Mass Index in Children with Juvenile Huntington’s Disease

2015 ◽  
Vol 4 (3) ◽  
pp. 231-238 ◽  
Author(s):  
Alexander Tereshchenko ◽  
Michael McHugh ◽  
Jessica K. Lee ◽  
Pedro Gonzalez-Alegre ◽  
Kaitlin Crane ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Body Mass ◽  
Juvenile Huntington’S Disease

The biopsychosocial assessment of people with low body mass index

2016 ◽  
Vol 20 (2) ◽  
pp. 64-71
Author(s):  
Funda Yıldırım Baş ◽  
Bahriye Arslan ◽  
Yasemin Türker
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Low Body Mass Index ◽  
Biopsychosocial Assessment

Predictors of nonroutine discharge among patients undergoing surgery for grade I spondylolisthesis: insights from the Quality Outcomes Database

2020 ◽  
Vol 32 (4) ◽  
pp. 523-532 ◽  
Author(s):  
Praveen V. Mummaneni ◽  
Mohamad Bydon ◽  
John Knightly ◽  
Mohammed Ali Alvi ◽  
Anshit Goyal ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Acute Care ◽  
Body Mass ◽  
Care Facility ◽  
Older Age ◽  
Quality Outcomes ◽  
Acute Care Facility ◽  
Factors Associated ◽  
Patient Reported ◽  
The Impact

OBJECTIVEDischarge to an inpatient rehabilitation facility or another acute-care facility not only constitutes a postoperative challenge for patients and their care team but also contributes significantly to healthcare costs. In this era of changing dynamics of healthcare payment models in which cost overruns are being increasingly shifted to surgeons and hospitals, it is important to better understand outcomes such as discharge disposition. In the current article, the authors sought to develop a predictive model for factors associated with nonroutine discharge after surgery for grade I spondylolisthesis.METHODSThe authors queried the Quality Outcomes Database for patients with grade I lumbar degenerative spondylolisthesis who underwent a surgical intervention between July 2014 and June 2016. Only those patients enrolled in a multisite study investigating the impact of fusion on clinical and patient-reported outcomes among patients with grade I spondylolisthesis were evaluated. Nonroutine discharge was defined as those who were discharged to a postacute or nonacute-care setting in the same hospital or transferred to another acute-care facility.RESULTSOf the 608 patients eligible for inclusion, 9.4% (n = 57) had a nonroutine discharge (8.7%, n = 53 discharged to inpatient postacute or nonacute care in the same hospital and 0.7%, n = 4 transferred to another acute-care facility). Compared to patients who were discharged to home, patients who had a nonroutine discharge were more likely to have diabetes (26.3%, n = 15 vs 15.7%, n = 86, p = 0.039); impaired ambulation (26.3%, n = 15 vs 10.2%, n = 56, p < 0.001); higher Oswestry Disability Index at baseline (51 [IQR 42–62.12] vs 46 [IQR 34.4–58], p = 0.014); lower EuroQol-5D scores (0.437 [IQR 0.308–0.708] vs 0.597 [IQR 0.358–0.708], p = 0.010); higher American Society of Anesthesiologists score (3 or 4: 63.2%, n = 36 vs 36.7%, n = 201, p = 0.002); and longer length of stay (4 days [IQR 3–5] vs 2 days [IQR 1–3], p < 0.001); and were more likely to suffer a complication (14%, n = 8 vs 5.6%, n = 31, p = 0.014). On multivariable logistic regression, factors found to be independently associated with higher odds of nonroutine discharge included older age (interquartile OR 9.14, 95% CI 3.79–22.1, p < 0.001), higher body mass index (interquartile OR 2.04, 95% CI 1.31–3.25, p < 0.001), presence of depression (OR 4.28, 95% CI 1.96–9.35, p < 0.001), fusion surgery compared with decompression alone (OR 1.3, 95% CI 1.1–1.6, p < 0.001), and any complication (OR 3.9, 95% CI 1.4–10.9, p < 0.001).CONCLUSIONSIn this multisite study of a defined cohort of patients undergoing surgery for grade I spondylolisthesis, factors associated with higher odds of nonroutine discharge included older age, higher body mass index, presence of depression, and occurrence of any complication.

Impact of Low Body Mass Index on Features of Coronary Culprit Plaques and Outcomes in Patients With Acute Coronary Syndrome

2021 ◽  
Author(s):  
Nobuaki Kobayashi ◽  
Yusaku Shibata ◽  
Osamu Kurihara ◽  
Takahiro Todoroki ◽  
Masayuki Tsutsumi ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Acute Coronary Syndrome ◽  
Body Mass ◽  
Coronary Syndrome ◽  
Low Body Mass Index
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