scholarly journals Substantia Nigra Echogenicity Predicts Response to Drug Withdrawal in Suspected Drug-Induced Parkinsonism

2015 ◽  
Vol 3 (3) ◽  
pp. 268-274 ◽  
Author(s):  
Jose L. López-Sendón Moreno ◽  
Araceli Alonso-Cánovas ◽  
Javier Buisán Catevilla ◽  
Nuria García Barragán ◽  
Iñigo Corral Corral ◽  
...  
Keyword(s):  
Substantia Nigra ◽  
Drug Withdrawal ◽  
Suspected Drug ◽  
Drug Induced ◽  
Substantia Nigra Echogenicity

scholarly journals Allopurinol-Induced Oral Lichenoid Drug Reaction with Complete Regression after Drug Withdrawal

2020 ◽  
Vol 7 (2) ◽  
pp. 18-25
Author(s):  
Alexandre Perez ◽  
Benjamin Lazzarotto ◽  
Jean-Pierre Carrel ◽  
Tommaso Lombardi
Keyword(s):  
Drug Reaction ◽  
Lichen Planus ◽  
Drug Withdrawal ◽  
Acute Onset ◽  
Complete Regression ◽  
Oral Manifestations ◽  
First Line ◽  
Drug Induced ◽  
Case Presentation ◽  
Oral Lichenoid Lesions

Background: Lichen planus is a chronic mucocutaneous inflammatory disease. Oral manifestations are common, and may remain exclusive to the oral mucosa without involvement of the skin or other mucosae. A differential diagnosis includes oral lichenoid drug reactions. Allopurinol, which is the first line hypo-uricemic treatment, is often quoted as being a possible offending drug, though oral reactions have rarely been reported. Case presentation: We describe a 59-year-old male gout patient, successfully treated with allopurinol, who developed acute onset of oral lichenoid lesions, involving bilaterally the buccal mucosa, the tongue and the labial mucosa. Histopathology was consistent with a lichen planus or a drug-induced lichenoid reaction. Improvement of the patient’s condition after withdrawal of allopurinol confirmed the lichenoid nature of the lesion. Remission was complete after a few weeks. Discussion: Although unusual, allopurinol may induce a lichenoid drug reaction. These reactions may mimic clinically and histopathologically idiopathic lichen planus. Improvement or complete regression of the lesions may be attempted to confirm the diagnosis. According to the latest WHO recommendations, these lesions have a potential for malignant transformation.

Lithium-Induced Parathyroid Dysfunction: A Case Report and Review of the Literature

1993 ◽  
Vol 27 (9) ◽  
pp. 1040-1043 ◽  
Author(s):  
Jerry W. Taylor ◽  
Angela J. Bell
Keyword(s):  
Case Report ◽  
Clinical Presentation ◽  
Lithium Carbonate ◽  
Suspected Drug ◽  
Current Management ◽  
Therapy Discontinuation ◽  
Drug Induced ◽  
Parathyroid Dysfunction ◽  
Management Recommendations

OBJECTIVE: Twenty-six cases of lithium-induced hyperparathyroidism have been reported in the literature. This article describes an additional case that illustrates current management recommendations. DESIGN: Case report. Clinical presentation and proposed mechanisms of the suspected drug-induced effect are discussed. CONCLUSIONS: Serum calcium concentrations should be determined before and periodically during long-term lithium carbonate therapy. Discontinuation of therapy in patients who develop lithium-induced parathyroid dysfunction generally corrects calcium and parathyroid hormone concentrations. Surgery is indicated in patients with complications of hyperparathyroidism.

scholarly journals Triggers of histologically suspected drug-induced colitis

2019 ◽  
Vol 25 (8) ◽  
pp. 967-979 ◽  
Author(s):  
Thorsten Brechmann ◽  
Katharina Günther ◽  
Matthias Neid ◽  
Wolff Schmiegel ◽  
Andrea Tannapfel
Keyword(s):  
Suspected Drug ◽  
Drug Induced

Substantia nigra echogenicity is correlated with nigrostriatal impairment in Machado-Joseph disease

2013 ◽  
Vol 19 (8) ◽  
pp. 742-745 ◽  
Author(s):  
José Luiz Pedroso ◽  
Edson Bor-Seng-Shu ◽  
André C. Felício ◽  
Pedro Braga-Neto ◽  
Marcelo Q. Hoexter ◽  
...  
Keyword(s):  
Substantia Nigra ◽  
Machado Joseph Disease ◽  
Substantia Nigra Echogenicity

Substantia Nigra Echogenicity in Friedreich’s Ataxia Patients

2012 ◽  
Vol 12 (4) ◽  
pp. 437-440 ◽  
Author(s):  
María Sierra ◽  
Jon Infante ◽  
José Berciano
Keyword(s):  
Substantia Nigra ◽  
Friedreich’S Ataxia ◽  
Friedreich's Ataxia ◽  
Substantia Nigra Echogenicity
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