scholarly journals Fixed Dystonia of the Tongue

2014 ◽  
Vol 1 (2) ◽  
pp. 134-135
Author(s):  
Roberto Erro ◽  
Carla Cordivari ◽  
Santiago Catania ◽  
Kailash P. Bhatia ◽  
Mark J. Edwards
Keyword(s):  
Fixed Dystonia

„Fixed dystonia“ syndrome after peripheral trauma in two adolescent girls

2010 ◽  
Vol 41 (02) ◽  
Author(s):  
K Müller ◽  
B Assmann ◽  
B Westhoff
Keyword(s):  
Adolescent Girls ◽  
Peripheral Trauma ◽  
Fixed Dystonia

scholarly journals Improvement of Secondary Fixed Dystonia of the Upper Limb After Chronic Extradural Motor Cortex Stimulation in 10 Patients

Neurosurgery ◽  
2011 ◽  
Vol 70 (5) ◽  
pp. 1169-1175 ◽  
Author(s):  
Giuseppe Messina ◽  
Roberto Cordella ◽  
Ivano Dones ◽  
Giovanni Tringali ◽  
Angelo Franzini
Keyword(s):  
Quality Of Life ◽  
Motor Cortex ◽  
Upper Limb ◽  
Short Form ◽  
The Body ◽  
Computer Assisted ◽  
Partial Recovery ◽  
Motor Cortex Stimulation ◽  
Fixed Dystonia

Abstract BACKGROUND: Fixed dystonic postures secondary to ischemic, traumatic, or postsurgical lesions located in the basal ganglia and brainstem constitute a major therapeutic challenge and limit motor rehabilitation efficacy. They are often refractory to conservative treatment. Aberrant cerebral plasticity developed after deep brain lesions is thought to lead to abnormal cortical representation of the affected part of the body and then to pathological fixed postures. OBJECTIVE: To assess the efficacy of motor cortex stimulation in patients with upper limb fixed dystonia. METHODS: Ten patients were submitted to computer-assisted and electromyography-monitored implantation of intracranial epidural electrodes over the central cortical sulcus contralateral to the affected limb. Patients were followed up from 1 to 9 years (9 patients), except for patient 10, whose follow-up was limited to 4 months. RESULTS: Seven of 7 patients showed > 30% improvement in the Disability of Shoulder, Arm, and Hand Scale and an overall 70% increase in the score of the Short Form-36 Physical Activity subscale with significant and stable improvement of quality of life during stimulation. The partial recovery of hand dexterity observed in most of the treated patients additionally contributed to a significant improvement of their quality of life. CONCLUSION: Although the pathophysiology of fixed dystonia is unknown, our results suggest a major role of the motor cortex in this condition and reinforce the hypothesis that postlesional delayed cortical rearrangements might take place in these forms and be the target of effective therapeutic neuromodulation.

HLA-B62 and HLA-DQ8 are associated with Complex Regional Pain Syndrome with fixed dystonia

Pain ◽  
2009 ◽  
Vol 145 (1) ◽  
pp. 82-85 ◽  
Author(s):  
Annetje M. de Rooij ◽  
Florencia M. Gosso ◽  
Geert W. Haasnoot ◽  
Johan Marinus ◽  
Willem Verduijn ◽  
...  
Keyword(s):  
Complex Regional Pain Syndrome ◽  
Pain Syndrome ◽  
Fixed Dystonia

The striking effects of deep cerebellar stimulation on generalized fixed dystonia: case report

2020 ◽  
Vol 132 (3) ◽  
pp. 712-716 ◽  
Author(s):  
Shiro Horisawa ◽  
Takashi Arai ◽  
Naoki Suzuki ◽  
Takakazu Kawamata ◽  
Takaomi Taira
Keyword(s):  
Present Report ◽  
Bound State ◽  
Intrathecal Baclofen ◽  
Superior Cerebellar Peduncle ◽  
Intrathecal Baclofen Therapy ◽  
Promising Treatment ◽  
Cerebellar Peduncle ◽  
Ipsilateral Stimulation ◽  
Better Than ◽  
Fixed Dystonia

Cerebellar neuromodulation could influence the pathological abnormalities of movement disorders through several connections between the cerebellum and the basal ganglia or other cortices. In the present report, the authors demonstrate the effects of cerebellar deep brain stimulation (DBS) on a patient with severe generalized fixed dystonia (FD) that was refractory to bilateral pallidotomy and intrathecal baclofen therapy. A previously healthy 16-year-old girl presented with generalized FD. Bilateral pallidotomy and intrathecal baclofen therapy had failed to resolve her condition, following which she received DBS through the bilateral superior cerebellar peduncle (SCP) and dentate nucleus (DN). Ipsilateral stimulation of the SCP or DN improved the FD, and the ability of DBS administered via the SCP to relax muscles was better than that of DN DBS. A considerable improvement of generalized FD, from a bedridden state to a wheelchair-bound state, was observed in the patient following 6 months of chronic bilateral DBS via the SCP; moreover, the patient was able to move her arms and legs. The findings in the present case suggest that neuromodulation of deep cerebellar structures is a promising treatment for FD that is refractory to conventional treatments.

Syndrome of fixed dystonia in adolescents – Short term outcome in 4 cases

2009 ◽  
Vol 13 (5) ◽  
pp. 466-472 ◽  
Author(s):  
Anirban Majumdar ◽  
Jesús López-Casas ◽  
Pilar Poo ◽  
Jaume Colomer ◽  
Marta Galvan ◽  
...  
Keyword(s):  
Short Term ◽  
Term Outcome ◽  
Short Term Outcome ◽  
Fixed Dystonia

scholarly journals Sudden onset, fixed dystonia and acute peripheral trauma as diagnostic clues for functional dystonia

2021 ◽  
Author(s):  
Tommaso Ercoli ◽  
Giovanni Defazio ◽  
Christian Geroin ◽  
Enrico Marcuzzo ◽  
Giovanni Fabbrini ◽  
...  
Keyword(s):  
Sudden Onset ◽  
Peripheral Trauma ◽  
Fixed Dystonia

The prognosis of fixed dystonia: A follow-up study

2009 ◽  
Vol 15 (8) ◽  
pp. 592-597 ◽  
Author(s):  
N.M. Ibrahim ◽  
D. Martino ◽  
B.P.C. van de Warrenburg ◽  
N.P. Quinn ◽  
K.P. Bhatia ◽  
...  
Keyword(s):  
Follow Up Study ◽  
Fixed Dystonia

Normal eyeblink classical conditioning in patients with fixed dystonia

2014 ◽  
Author(s):  
Sabine Janssen ◽  
Lidwien C. Veugen ◽  
Britt S. Hoffland ◽  
Panagiotis Kassavetis ◽  
Diana E. van Rooijen ◽  
...  
Keyword(s):  
Classical Conditioning ◽  
Fixed Dystonia
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