Homozygous deletions but no sequence mutations in coding regions ofp15 orp16 in human primary bladder tumors

1995 ◽  
Vol 14 (3) ◽  
pp. 147-151 ◽  
Author(s):  
Joan P. Packenham ◽  
Jack A. Taylor ◽  
Colleen H. Anna ◽  
Catherine M. White ◽  
Theodora R. Devereux
Keyword(s):  
Bladder Tumors ◽  
Coding Regions ◽  
Primary Bladder ◽  
Homozygous Deletions

Analysis of p21WAF1/CIP1 in Primary Bladder Tumors

1998 ◽  
Vol 159 (5) ◽  
pp. 1770-1770
Author(s):  
L. Lacombe ◽  
I. Orlow ◽  
D. Silver ◽  
W.L. Gerald ◽  
W.R. Fair ◽  
...  
Keyword(s):  
Bladder Tumors ◽  
Primary Bladder

Secondary Malignancies of the Bladder: Avoiding the Diagnostic Pitfall

2017 ◽  
Vol 26 (2) ◽  
pp. 120-125 ◽  
Author(s):  
Alexander Feldman ◽  
Samuel Borak ◽  
Soroush Rais-Bahrami ◽  
Jennifer Gordetsky
Keyword(s):  
Metastatic Tumor ◽  
Clinical History ◽  
Prior History ◽  
Bladder Tumors ◽  
Diagnostic Dilemma ◽  
Secondary Tumors ◽  
Diagnostic Pitfall ◽  
Imaging Characteristics ◽  
History Of ◽  
Primary Bladder

Although rare, secondary tumors of the bladder can present a diagnostic dilemma to pathologists considering a differential diagnosis of primary bladder cancer. We investigated the clinicopathologic and imaging characteristics of metastatic tumors to the bladder. We retrospectively reviewed the surgical pathology databases from 2 sites from 2013 to 2016, identifying 66 cases of secondary bladder tumors. Clinical, pathologic, and imaging findings were reviewed. Mean age at diagnosis was 63 years (range = 25-87). Females had a significantly higher proportion (44/66, 66.7%) of secondary bladder tumors compared with males (22/66, 33.3%; P = .007). In total, 56/66 (84.8%) patients had a clinical history of an in situ or invasive malignancy in another organ, and 54/66 (81.8%) patients had imaging supporting a metastatic tumor. Only 2/66 (3.0%) patients had a prior history of urothelial carcinoma. In total, 4/66 (6.1%) cases (all females) were originally misdiagnosed as primary bladder malignancies and were corrected after clinicoradiologic correlation. Overall, colorectal origin was most common (15/66, 22.7%), followed by cervical and ovarian primaries (10/66, 15.2% each). Cervical and ovarian origins predominated in the female cohort (10/44, 22.7% each), followed by endometrial (8/44, 18.2%). Colorectal and prostate primaries were the most common among males (10/22, 45.5%, and 7/22, 31.8%, respectively). Secondary bladder tumors can mimic urothelial carcinomas. In our cohort, gynecological, colorectal, and prostatic origins were most common. Clinical history, imaging, and immunohistochemical studies can be useful in avoiding this diagnostic pitfall.

Partial Cystectomy for Primary Bladder Tumors in Contemporary Patients with Diverse Tumor Locations

2016 ◽  
Vol 3 (1) ◽  
pp. 55-61
Author(s):  
Matthew R. Danzig ◽  
Ari R. Berg ◽  
Rashed A. Ghandour ◽  
Danny Lascano ◽  
Michael J. Whalen ◽  
...  
Keyword(s):  
Partial Cystectomy ◽  
Bladder Tumors ◽  
Primary Bladder

Ten-Year Analysis of Primary Bladder Tumors at Brooke General Hospital

1964 ◽  
Vol 91 (5) ◽  
pp. 530-532 ◽  
Author(s):  
Robert J. Marsh ◽  
Frank E. Ceccarelli
Keyword(s):  
General Hospital ◽  
Bladder Tumors ◽  
Primary Bladder

The natural history, treatment pattern, and survival of the patients with micropapillary bladder.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e15015-e15015
Author(s):  
Jue Wang
Keyword(s):  
Natural History ◽  
Tumor Stage ◽  
Invasive Disease ◽  
Population Based ◽  
Bladder Tumors ◽  
Cancer Specific Survival ◽  
Undifferentiated Histology ◽  
Primary Bladder ◽  
Muscle Invasive ◽  
Population Based Registry

e15015 Background: Micropapillary bladder carcinoma (MPBC) is a rare variant of urothelial carcinoma. The objective of this study was to examine the epidemiology, natural history, and prognostic factors of MPBC using population-based registry. Methods: The Surveillance, Epidemiology, and End Results (SEER) Program database was used to identify cases of MPBC by tumor site and histology codes. The clinical, demographic characteristics, treatment and survival of MPBC were examined. Results: A total of 98 cases of histology confirmed MPBC were identified between 2001 and 2007, this accounted for approximately 0.01% of all primary bladder tumors during the study period. Median age of the patients was 72 years (range 26-95). Of all the patients with MPBC, 56.1% had muscle invasive disease; 75.5% of patients had poorly or undifferentiated histology. A total of 30.6% of all patients (2.3% superficial disease; 52.7% of muscle-invasive MPBC) had radical or partial cystectomy. By logistic regression analysis, nonmuscle-invasive MPBC (OR 62.5, 95% CI 7.2-542.3) was associated with lower rate of utilization of cystectomy. The 1-, 3- and 5-year overall survival rate of MPBC were 84.5%, 57.3% and 42.3%. In multivariate analysis, tumor stage (HR 4.7, 95% CI 1.0-21.8) was found to be the only significant predictor for cancer-specific survival. Conclusions: The optimal therapy for MPBC remains undermined. Emphasis on early detection is needed to improve the outcome for patients with this malignancy.

COMPARABLE RISK OF PROGRESSION IN HIGH GRADE TA AND STAGE T1 PRIMARY BLADDER TUMORS FOLLOWING TUR AND INTRAVESICAL BCG THERAPY

2009 ◽  
Vol 181 (4) ◽  
pp. 636
Author(s):  
Yasuo Kohjimoto ◽  
Nagahide Matsumura ◽  
Yasuyo Shintani ◽  
Takeshi Inagaki ◽  
Isao Hara
Keyword(s):  
High Grade ◽  
Bladder Tumors ◽  
Bcg Therapy ◽  
Intravesical Bcg ◽  
Risk Of Progression ◽  
Primary Bladder ◽  
Intravesical Bcg Therapy ◽  
Stage T1

80P HER2 expression in primary bladder tumors and paired regional lymph nodes: Relationship to cell cycle profile

2021 ◽  
Vol 32 ◽  
pp. S1369-S1370
Author(s):  
M. Dumitru ◽  
M. Mihăilă ◽  
C.M. Hotnog ◽  
M.E. Panait ◽  
M.M. Vasilescu ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Lymph Nodes ◽  
Her2 Expression ◽  
Bladder Tumors ◽  
Regional Lymph Nodes ◽  
Cell Cycle Profile ◽  
Primary Bladder

scholarly journals MP48-20 EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES (TIL) FROM PRIMARY BLADDER TUMORS

2017 ◽  
Vol 197 (4S) ◽  
Author(s):  
Michael Poch ◽  
Maclean Hall ◽  
Krithika Kodumudi Kodumudi ◽  
Cortlin Croft ◽  
Mayer Fishman ◽  
...  
Keyword(s):  
Tumor Infiltrating Lymphocytes ◽  
Bladder Tumors ◽  
Primary Bladder ◽  
Infiltrating Lymphocytes

scholarly journals Primary bladder angiosarcoma synchronous with prostatic acinar adenocarcinoma in an 82-year-old male

2020 ◽  
Vol 07 (03) ◽  
pp. 52-56
Author(s):  
Cătălina Paranici ◽  
Sanda Achim ◽  
Valentin Enache
Keyword(s):  
Soft Tissue ◽  
Urinary Bladder ◽  
Clinical Outcome ◽  
English Literature ◽  
Soft Tissue Sarcomas ◽  
Clinical History ◽  
Bladder Tumors ◽  
Primary Angiosarcoma ◽  
Primary Bladder

Primary bladder angiosarcoma is a rarely encountered and poorly described malignancy. Only 34 cases have been described in the English literature according to PubMed, accounting for only 2% of the genitourinary soft tissue sarcomas and 0.6% of all bladder tumors. We report a case of a primary angiosarcoma of the urinary bladder in an 82-year-old patient and present the clinical history, histopathological and immunohistochemical features of this tumor, in order to provide better understanding of the diagnosis, possible therapies and clinical outcome.

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