Neurotensin receptor 1 is a new therapeutic target for human undifferentiated pleomorphic sarcoma growth

2019 ◽  
Vol 58 (12) ◽  
pp. 2230-2240
Author(s):  
Hiroto Tokumoto ◽  
Takao Setoguchi ◽  
Yoshinobu Saitoh ◽  
Hiromi Sasaki ◽  
Satoshi Nagano ◽  
...  
Keyword(s):  
Therapeutic Target ◽  
Undifferentiated Pleomorphic Sarcoma ◽  
Neurotensin Receptor ◽  
Pleomorphic Sarcoma ◽  
Neurotensin Receptor 1

Undifferentiated Pleomorphic Sarcoma of Lower Extremity

2017 ◽  
Vol 4 (2) ◽  
pp. 102-104
Author(s):  
Sunil Vitthalrao Jagtap ◽  
◽  
Cyrus Dara Jokhi ◽  
Swati S Jagtap ◽  
Ritvij Patankar ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Undifferentiated Pleomorphic Sarcoma ◽  
Pleomorphic Sarcoma

scholarly journals Undifferentiated pleomorphic sarcoma in oropharyngeal mucosa of patients with multiple basal cell carcinomas

Rare Tumors ◽  
2021 ◽  
Vol 13 ◽  
pp. 203636132110264
Author(s):  
Andrea Dekanić ◽  
Marko Velepič ◽  
Margita Belušić Gobić ◽  
Ita Hadžisejdić ◽  
Nives Jonjić
Keyword(s):  
Differential Diagnosis ◽  
Basal Cell ◽  
Polypoid Lesion ◽  
Older Patient ◽  
Mesenchymal Tumors ◽  
Undifferentiated Pleomorphic Sarcoma ◽  
Pleomorphic Sarcoma ◽  
Basal Cell Carcinomas ◽  
History Of ◽  
Multiple Basal Cell Carcinomas

Malignant mesenchymal tumors of oropharyngeal mucosa are rare. Those with fibroblastic and histiocytic differentiation in the skin are called atypical fibroxanthoma (AFX) and in the soft tissue undifferentiated pleomorphic sarcoma (UPS). Here we present a case of an older patient with a history of multiple basal cell carcinomas and recently with a rapidly growing polypoid lesion in the mucosa of posterior oropharyngeal wall with AFX/UPS morphology. The differential diagnosis, histological pitfalls of this poorly characterized mesenchymal lesions, and the challenges associated with treatment are discussed.

Undifferentiated Pleomorphic Sarcoma of Vulva

2020 ◽  
Vol 18 (3) ◽  
Author(s):  
Amita Naithani ◽  
Parul Sharma ◽  
R. Pratima ◽  
Priyanka Makkar ◽  
Sunil Pasricha ◽  
...  
Keyword(s):  
Undifferentiated Pleomorphic Sarcoma ◽  
Pleomorphic Sarcoma

scholarly journals Splenic undifferentiated high grade pleomorphic sarcoma of a small size with fatal tumor rupture

1970 ◽  
Vol 1 (2) ◽  
pp. 151-153 ◽  
Author(s):  
BM Amatya ◽  
M Sawabe ◽  
T Arai ◽  
T Kumakawa ◽  
K Takubo ◽  
...  
Keyword(s):  
Past History ◽  
Distant Metastases ◽  
Tumor Rupture ◽  
Retroperitoneal Hemorrhage ◽  
Undifferentiated Pleomorphic Sarcoma ◽  
Bone Marrow Histology ◽  
Pleomorphic Sarcoma ◽  
Fatal Bleeding ◽  
History Of ◽  
The Right

(The order of authors on this article was changed on 09/01/2012.)Primary undifferentiated pleomorphic sarcoma of the spleen is a rare and highly aggressive neoplasm that usually presents with splenomegaly, constitutional symptoms and frequent distant metastases. We report a case of 77-year old male patient with a past history of dissecting aortic aneurysm that developed acute hemorrhagic shock. Aneurysmal rupture was clinically suspected, but the postmortem examination revealed a 25 mm-sized tumor in an atrophic spleen weighing 65 gram with massive retroperitoneal bleeding. Metastases were found in the right renal hilus, the right adrenal gland and femoral bone marrow. Histology of the tumor showed undifferentiated pleomorphic sarcoma. Tumor rupture with fatal bleeding and systemic metastases had occurred despite the small size of the tumor. Tumor size is not a reliable predictor of systemic metastasis or tumor rupture for splenic undifferentiated pleomorphic sarcoma. Keywords: Undifferentiated pleomorphic sarcoma; Malignant fibrous histiocytoma; Splenic neoplasms; Retroperitoneal hemorrhage DOI: http://dx.doi.org/10.3126/jpn.v1i2.5411 JPN 2011; 1(2): 151-153

scholarly journals Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma

2018 ◽  
Vol 144 (4) ◽  
pp. 859-867 ◽  
Author(s):  
Martin F. Orth ◽  
Julia S. Gerke ◽  
Thomas Knösel ◽  
Annelore Altendorf-Hofmann ◽  
Julian Musa ◽  
...  
Keyword(s):  
Functional Genomics ◽  
Prognostic Marker ◽  
Undifferentiated Pleomorphic Sarcoma ◽  
Pleomorphic Sarcoma
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