scholarly journals Ectopic expression of PLC‐β2 in non‐invasive breast tumor cells plays a protective role against malignant progression and is correlated with the deregulation of miR‐146a

2019 ◽  
Vol 58 (5) ◽  
pp. 708-721 ◽  
Author(s):  
Valeria Bertagnolo ◽  
Silvia Grassilli ◽  
Stefano Volinia ◽  
Yasamin Al‐Qassab ◽  
Federica Brugnoli ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Breast Tumor ◽  
Ectopic Expression ◽  
Protective Role ◽  
Malignant Progression ◽  
Breast Tumor Cells ◽  
Non Invasive ◽  
Invasive Breast Tumor

scholarly journals Ethanol-based garlic extract prevents malignant evolution of non-invasive breast tumor cells induced by moderate hypoxia

2021 ◽  
Vol 142 ◽  
pp. 112052
Author(s):  
Federica Brugnoli ◽  
Paola Tedeschi ◽  
Silvia Grassilli ◽  
Annalisa Maietti ◽  
Vincenzo Brandolini ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Breast Tumor ◽  
Garlic Extract ◽  
Moderate Hypoxia ◽  
Breast Tumor Cells ◽  
Non Invasive ◽  
Invasive Breast Tumor

Ectopic expression of hC/EBPs in breast tumor cells induces apoptosis

2009 ◽  
Vol 337 (1-2) ◽  
pp. 111-118 ◽  
Author(s):  
Pooja Pal ◽  
Savita Lochab ◽  
Jitendra Kanaujiya ◽  
Sabyasachi Sanyal ◽  
Arun Kumar Trivedi
Keyword(s):  
Tumor Cells ◽  
Breast Tumor ◽  
Ectopic Expression ◽  
Breast Tumor Cells

A Non-Invasive Approach for Monitoring Breast Tumor Cells During Therapeutic Intervention

2002 ◽  
Vol 17 (2) ◽  
pp. 205-212 ◽  
Author(s):  
Tandra R. Chaudhuri ◽  
Zhihong Cao ◽  
Cristina Rodríguez-Burford ◽  
Albert F. LoBuglio ◽  
Kurt R. Zinn
Keyword(s):  
Tumor Cells ◽  
Therapeutic Intervention ◽  
Breast Tumor ◽  
Invasive Approach ◽  
Breast Tumor Cells ◽  
Non Invasive

scholarly journals Immunonanoparticles − an effective tool to impair harmful proteolysis in invasive breast tumor cells

FEBS Journal ◽  
2007 ◽  
Vol 274 (17) ◽  
pp. 4416-4427 ◽  
Author(s):  
Nataša Obermajer ◽  
Petra Kocbek ◽  
Urška Repnik ◽  
Alenka Kužnik ◽  
Mateja Cegnar ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Breast Tumor ◽  
Breast Tumor Cells ◽  
Invasive Breast Tumor

scholarly journals MicroRNAs as the critical regulators of Doxorubicin resistance in breast tumor cells

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Amir Sadra Zangouei ◽  
Maliheh Alimardani ◽  
Meysam Moghbeli
Keyword(s):  
Drug Resistance ◽  
Side Effects ◽  
Tumor Cells ◽  
Clinical Outcomes ◽  
Breast Tumor ◽  
Present Review ◽  
Multi Drug Resistance ◽  
Main Body ◽  
Breast Tumor Cells ◽  
Non Invasive

Abstract Background Chemotherapy is one of the most common treatment options for breast cancer (BC) patients. However, about half of the BC patients are chemotherapeutic resistant. Doxorubicin (DOX) is considered as one of the first line drugs in the treatment of BC patients whose function is negatively affected by multi drug resistance. Due to the severe side effects of DOX, it is very important to diagnose the DOX resistant BC patients. Therefore, assessment of molecular mechanisms involved in DOX resistance can improve the clinical outcomes in BC patients by introducing the novel therapeutic and diagnostic molecular markers. MicroRNAs (miRNAs) as members of the non-coding RNAs family have pivotal roles in various cellular processes including cell proliferation and apoptosis. Therefore, aberrant miRNAs functions and expressions can be associated with tumor progression, metastasis, and drug resistance. Moreover, due to miRNAs stability in body fluids, they can be considered as non-invasive diagnostic markers for the DOX response in BC patients. Main body In the present review, we have summarized all of the miRNAs that have been reported to be associated with DOX resistance in BC for the first time in the world. Conclusions Since, DOX has severe side effects; it is required to distinguish the non DOX-responders from responders to improve the clinical outcomes of BC patients. This review highlights the miRNAs as pivotal regulators of DOX resistance in breast tumor cells. Moreover, the present review paves the way of introducing a non-invasive panel of prediction markers for DOX response among BC patients.

scholarly journals Protective role of all-trans retinoic acid (ATRA) against hypoxia-induced malignant potential of non-invasive breast tumor derived cells

BMC Cancer ◽  
2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Yasamin Al-Qassab ◽  
Silvia Grassilli ◽  
Federica Brugnoli ◽  
Federica Vezzali ◽  
Silvano Capitani ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Breast Tumor ◽  
Protective Role ◽  
Malignant Potential ◽  
Non Invasive ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid ◽  
Invasive Breast Tumor
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