ATG12 expression quantitative trait loci associated with head and neck squamous cell carcinoma risk in a Chinese Han population

2018 ◽  
Vol 57 (8) ◽  
pp. 1030-1037 ◽  
Author(s):  
Xueyao Song ◽  
Zhiyao Yuan ◽  
Hua Yuan ◽  
Lihua Wang ◽  
Pei Ji ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Quantitative Trait Loci ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Quantitative Trait ◽  
Neck Squamous Cell Carcinoma ◽  
Chinese Han ◽  
Han Population ◽  
Carcinoma Risk

scholarly journals The Genetic Polymorphisms in the MIR17HG Gene Are Associated with the Risk of Head and Neck Squamous Cell Carcinoma in the Chinese Han Population

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Chongwen Xu ◽  
Peng Han ◽  
Wanli Ren ◽  
Hao Dai ◽  
Yanxia Bai ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Malignant Tumors ◽  
Protective Role ◽  
Neck Squamous Cell Carcinoma ◽  
Chinese Han Population ◽  
Chinese Han ◽  
Han Population

Purpose. Head and neck squamous cell carcinoma (HNSCC) is the most common malignant tumors in the world. Genetic variants have an important role in HNSCC progression. Our study is aimed at exploring the relationship between MIR17HG polymorphisms and HNSCC risk in the Chinese Han population. Methods. We recruited 537 HNSCC cases and 533 healthy subjects to detect the correlation of six polymorphisms in MIR17HG with HNSCC susceptibility. The associations were evaluated by computing odds ratios (ORs) and 95% confidence intervals (CIs) using logistic regression analysis. Results. Our study revealed that rs7336610 (OR 1.77, 95 % CI = 1.09 ‐ 2.86 , and p = 0.021 ) and rs1428 (OR 1.73, 95 % CI = 1.07 ‐ 2.81 , and p = 0.025 ) are strongly associated with increased susceptibility to HNSCC in men. Besides, rs17735387 played a crucial protective role in stage III/IV HNSCC patients (OR 0.34, 95 % CI = 0.12 ‐ 0.95 , and p = 0.040 ) compared with stage I/II. Conclusion. Our study firstly indicated that MIR17HG polymorphisms are significantly associated with HNSCC susceptibility, which suggests that MIR17HG has a potential role in the occurrence of HNSCC.

Polymorphisms of the CYP1A1 and CYP2E1 genes in head and neck squamous cell carcinoma risk

2011 ◽  
Vol 39 (2) ◽  
pp. 1055-1063 ◽  
Author(s):  
Nathália Moreno Cury ◽  
Anelise Russo ◽  
Ana Lívia Silva Galbiatti ◽  
Mariângela Torreglosa Ruiz ◽  
Luiz Sérgio Raposo ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Carcinoma Risk

Polymorphisms and haplotypes in methylenetetrahydrofolate reductase gene and head and neck squamous cell carcinoma risk

2011 ◽  
Vol 39 (1) ◽  
pp. 635-643 ◽  
Author(s):  
Ana Lívia Silva Galbiatti ◽  
Mariangela Torreglosa Ruiz ◽  
Juliana Olsen Rodrigues ◽  
Luiz Sérgio Raposo ◽  
José Victor Maníglia ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Methylenetetrahydrofolate Reductase ◽  
Neck Squamous Cell Carcinoma ◽  
Reductase Gene ◽  
Carcinoma Risk ◽  
Methylenetetrahydrofolate Reductase Gene

MTHFD1 G1958A, BHMT G742A, TC2 C776G and TC2 A67G polymorphisms and head and neck squamous cell carcinoma risk

2011 ◽  
Vol 39 (2) ◽  
pp. 887-893 ◽  
Author(s):  
Lidia Maria Rebolho Batista da Silva ◽  
Ana Lívia Silva Galbiatti ◽  
Mariangela Torreglosa Ruiz ◽  
Luiz Sérgio Raposo ◽  
José Victor Maniglia ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Carcinoma Risk

scholarly journals Single Nucleotide Polymorphism of MSH3 Gene Alters Head and Neck Squamous-Cell Carcinoma Risk in North-India

2017 ◽  
Vol 14 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Suresh Kumar Yadav ◽  
Shalini Gupta ◽  
Madan Lal Brahma Bhatt ◽  
Durga Prasad Mishra ◽  
Dayalanand Roy ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Single Nucleotide Polymorphism ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
North India ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide ◽  
Carcinoma Risk
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