TGFBR1tagging SNPs and gastric cancer susceptibility: A two-stage case-control study in chinese population

2012 ◽  
Vol 53 (2) ◽  
pp. 109-116 ◽  
Author(s):  
Jianjian Chen ◽  
Lin Miao ◽  
Guangfu Jin ◽  
Chuanli Ren ◽  
Qiao Ke ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Chinese Population ◽  
Case Control Study ◽  
Cancer Susceptibility ◽  
Case Control ◽  
Two Stage ◽  
Control Study

scholarly journals Polymorphisms in CARS are associated with gastric cancer risk: a two-stage case–control study in the Chinese population

2017 ◽  
Vol 20 (6) ◽  
pp. 940-947 ◽  
Author(s):  
Tian Tian ◽  
Ling Xiao ◽  
Jiangbo Du ◽  
Xun Zhu ◽  
Yayun Gu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Risk ◽  
Chinese Population ◽  
Case Control Study ◽  
Case Control ◽  
Gastric Cancer Risk ◽  
Two Stage ◽  
Control Study

scholarly journals Predictive Value of MiR-219-1, MiR-938, MiR-34b/c, and MiR-218 Polymorphisms for Gastric Cancer Susceptibility and Prognosis

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Yanhua Wu ◽  
Zhifang Jia ◽  
Donghui Cao ◽  
Chuan Wang ◽  
Xing Wu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Survival Analysis ◽  
Distant Metastasis ◽  
Case Control Study ◽  
Cancer Susceptibility ◽  
Case Control ◽  
Cancer Prognosis ◽  
Radical Operation ◽  
Risk Of Death ◽  
Control Study

Gastric cancer (GC) is one of the most prominent global cancer-related health threats. Genes play a key role in the precise mechanisms of gastric cancer. SNPs in mi-RNAs could affect mRNA expression and then affect the risk and prognosis of GC. Firstly, we have decided to perform a case-control study which included 897 GC patients and 992 controls to evaluate the association of miR-219-1 rs213210, miR-938 rs2505901, miR-34b/c rs4938723, and miR-218 rs11134527 polymorphisms with gastric cancer susceptibility. Secondly, among the 897 GC patients above, 755 cases underwent a radical operation, without distant metastasis and with negative surgical margins included in the survival analysis to evaluate the association of the four SNPs above with gastric cancer prognosis. The C/T or C/C genotypes of rs213210 were related to a lower GC risk (OR = 0.76, 95% CI: 0.62–0.93,P=0.009) compared to the T/T genotype. Rs11134527 in miR-218 was associated with GC survival, and the G/A and G/G genotypes of rs11134527 resulted in a decreased risk of death when compared with the A/A genotype (HR = 0.75, 95% CI: 0.61–0.95,P=0.016). This study found that miR-219-1 rs213210 polymorphism was associated with GC susceptibility and rs11134527 in miR-218 was positively correlated with GC prognosis.

scholarly journals Polymorphisms of XRCC1 and ADPRT Genes and Risk of Noncardia Gastric Cancer in a Chinese Population: a Case-control Study

2012 ◽  
Vol 13 (11) ◽  
pp. 5637-5642 ◽  
Author(s):  
Xiong-Fei Pan ◽  
Yao Xie ◽  
Marie Loh ◽  
Shu-Juan Yang ◽  
Yuan-Yuan Wen ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Chinese Population ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals XPG Gene Polymorphisms Contribute to Colorectal Cancer Susceptibility: A Two-Stage Case-Control Study

2016 ◽  
Vol 7 (12) ◽  
pp. 1731-1739 ◽  
Author(s):  
Rui-Xi Hua ◽  
Zhen-Jian Zhuo ◽  
Jinhong Zhu ◽  
Shao-Dan Zhang ◽  
Wen-Qiong Xue ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Gene Polymorphisms ◽  
Case Control Study ◽  
Cancer Susceptibility ◽  
Case Control ◽  
Two Stage ◽  
Control Study
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