Use of Ti in hard metal alloys - Part II: mechanical properties. Titan in Hartmetallen - Teil II: Mechanische Eigenschaften

Different biomaterials in the form of ceramics, metal alloys, composites, glasses, polymers, etc. have gained wide-range acceptance in the realm of medical sciences. Bioimplants from such biomaterials have been constructed and used widely for different clinical applications. With the continual progress, biomaterials that may be resorbed inside the body have been developed. These have done away with the major challenge of removal of an implant after it has served its intended function. Important factors are taken into consideration in design and development of implants from such biomaterials are mechanical properties, degradation rate, surface modification, rate of corrosion, biocompatibility, and non-toxicity. Given the importance of such materials in clinical applications, the chapter presents an overview of the bioresorable composites and their implants. The related properties and the functions served have been outlined briefly. Further, the challenges associated and the remedies to overcome them have also been delineated.

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Bioresorbable Composites and Implant

Research Anthology on Emerging Technologies and Ethical Implications in Human Enhancement ◽

10.4018/978-1-7998-8050-9.ch022 ◽

2021 ◽

pp. 443-456

Author(s):

Divya Zindani

Keyword(s):

Mechanical Properties ◽

Surface Modification ◽

Degradation Rate ◽

Clinical Applications ◽

The Body ◽

Metal Alloys ◽

Medical Sciences ◽

Intended Function ◽

Wide Range ◽

Modification Rate

Different biomaterials in the form of ceramics, metal alloys, composites, glasses, polymers, etc. have gained wide-range acceptance in the realm of medical sciences. Bioimplants from such biomaterials have been constructed and used widely for different clinical applications. With the continual progress, biomaterials that may be resorbed inside the body have been developed. These have done away with the major challenge of removal of an implant after it has served its intended function. Important factors are taken into consideration in design and development of implants from such biomaterials are mechanical properties, degradation rate, surface modification, rate of corrosion, biocompatibility, and non-toxicity. Given the importance of such materials in clinical applications, the chapter presents an overview of the bioresorable composites and their implants. The related properties and the functions served have been outlined briefly. Further, the challenges associated and the remedies to overcome them have also been delineated.

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Improved Bioactivity of 3D Printed Porous Titanium Alloy Scaffold with Chitosan/Magnesium-Calcium Silicate Composite for Orthopaedic Applications

Materials ◽

10.3390/ma12020203 ◽

2019 ◽

Vol 12 (2) ◽

pp. 203 ◽

Cited By ~ 18

Author(s):

Chun-Hao Tsai ◽

Chih-Hung Hung ◽

Che-Nan Kuo ◽

Cheng-Yu Chen ◽

Yu-Ning Peng ◽

...

Keyword(s):

Mechanical Properties ◽

Calcium Silicate ◽

Cell Attachment ◽

Three Dimensional ◽

Bone Defects ◽

Metal Alloys ◽

Potential Candidate ◽

Natural Bone

Recently, cases of bone defects have been increasing incrementally. Thus, repair or replacement of bone defects is gradually becoming a huge problem for orthopaedic surgeons. Three-dimensional (3D) scaffolds have since emerged as a potential candidate for bone replacement, of which titanium (Ti) alloys are one of the most promising candidates among the metal alloys due to their low cytotoxicity and mechanical properties. However, bioactivity remains a problem for metal alloys, which can be enhanced using simple immersion techniques to coat bioactive compounds onto the surface of Ti–6Al–4V scaffolds. In our study, we fabricated magnesium-calcium silicate (Mg–CS) and chitosan (CH) compounds onto Ti–6Al–4V scaffolds. Characterization of these surface-modified scaffolds involved an assessment of physicochemical properties as well as mechanical testing. Adhesion, proliferation, and growth of human Wharton’s Jelly mesenchymal stem cells (WJMSCs) were assessed in vitro. In addition, the cell attachment morphology was examined using scanning electron microscopy to assess adhesion qualities. Osteogenic and mineralization assays were conducted to assess osteogenic expression. In conclusion, the Mg–CS/CH coated Ti–6Al–4V scaffolds were able to exhibit and retain pore sizes and their original morphologies and architectures, which significantly affected subsequent hard tissue regeneration. In addition, the surface was shown to be hydrophilic after modification and showed mechanical strength comparable to natural bone. Not only were our modified scaffolds able to match the mechanical properties of natural bone, it was also found that such modifications enhanced cellular behavior such as adhesion, proliferation, and differentiation, which led to enhanced osteogenesis and mineralization downstream. In vivo results indicated that Mg–CS/CH coated Ti–6Al–4V enhances the bone regeneration and ingrowth at the critical size bone defects of rabbits. These results indicated that the proposed Mg–CS/CH coated Ti–6Al–4V scaffolds exhibited a favorable, inducive micro-environment that could serve as a promising modification for future bone tissue engineering scaffolds.

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Structure and mechanical properties of internally hydrided Mg-IIIa transition metal alloys

Journal of Materials Science ◽

10.1007/bf00366365 ◽

1996 ◽

Vol 31 (17) ◽

pp. 4647-4654 ◽

Cited By ~ 3

Author(s):

S. Morozumi ◽

H. Saikawa ◽

T. Minegishi ◽

M. Matsuyama ◽

K. Watanabe ◽

...

Keyword(s):

Mechanical Properties ◽

Transition Metal ◽

Metal Alloys ◽

Transition Metal Alloys

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