Tuning Mechanical Properties of Chondroitin Sulfate-Based Double-Network Hydrogels

2013 ◽  
Vol 329 (1) ◽  
pp. 9-18 ◽  
Author(s):  
Tiffany C. Suekama ◽  
Jian Hu ◽  
Takayuki Kurokawa ◽  
Jian Ping Gong ◽  
Stevin H. Gehrke
2014 ◽  
Vol 1622 ◽  
pp. 79-84
Author(s):  
Tiffany C Suekama ◽  
Anahita Khanlari ◽  
Stevin H Gehrke

ABSTRACTThe double-network (DN) hydrogel concept developed by J.P. Gong and Y. Osada builds upon interpenetrating networks by combining brittle and ductile components to have significantly enhanced fracture properties. The generality of the DN effect was tested by creating biopolymer-based hydrogels of methacrylated chondroitin sulfate (MCS) and polyacrylamide (PAAm) and extended upon creating DNs of MCS and poly(N,N dimethyl acrylamide) (PDMAAm), verifying that DNs were not limited to the original combination of poly(2-acrylamido-2-methylpropanesulfonic acid) (PAMPS)/polyacrylamide (PAAm). Further, the mechanical properties were varied by changing the monomer concentrations, cross-linker concentrations and the addition of cross-linking groups through copolymerizations of MCS and poly(ethylene glycol) diacrylate (PEGDA). Overall, this work demonstrates that a broad range of mechanical properties achievable through DN effect under tension and compression, generally independent of the swelling degree, which is fundamentally different behavior than possible with single networks.


2019 ◽  
Vol 35 (3) ◽  
pp. 371-391
Author(s):  
AKANSHA DIXIT ◽  
◽  
DIBYENDU S. BAG ◽  
DHIRENDRA KUMAR SHARMA ◽  
HARJEET SINGH ◽  
...  

2017 ◽  
Vol 38 (20) ◽  
pp. 1700351 ◽  
Author(s):  
A. Kristen Means ◽  
Daniel A. Ehrhardt ◽  
Lauren V. Whitney ◽  
Melissa A. Grunlan

2021 ◽  
Author(s):  
Ming Yan ◽  
Junfeng Shi ◽  
Song Tang ◽  
Guohang Zhou ◽  
Jiexiang Zeng ◽  
...  

The SA/PAA-VSNP fiber was obtained using dynamic wet spinning through dynamic hydrogen bonding in the double network structure.


2021 ◽  
pp. 2100361
Author(s):  
Zeyu Zhang ◽  
Tingrui Lin ◽  
Shuangxiao Li ◽  
Xibang Chen ◽  
Xueyan Que ◽  
...  

2018 ◽  
Vol 163 ◽  
pp. 81-88 ◽  
Author(s):  
Xiaoqiang Yan ◽  
Jia Yang ◽  
Feng Chen ◽  
Lin Zhu ◽  
Ziqing Tang ◽  
...  

2015 ◽  
Vol 3 (9) ◽  
pp. 1769-1778 ◽  
Author(s):  
Zhiyong Li ◽  
Yunlan Su ◽  
Baoquan Xie ◽  
Xianggui Liu ◽  
Xia Gao ◽  
...  

A novel physically linked double-network (DN) hydrogel was prepared by natural polymer KGM and synthetic polymer PAAm. The DN hydrogels exhibit good mechanical properties, cell adhesion properties, and can be freely shaped, making such hydrogels promising for tissue engineering scaffolds.


Soft Matter ◽  
2020 ◽  
Vol 16 (28) ◽  
pp. 6582-6590 ◽  
Author(s):  
Jacob G. Turner ◽  
Jun Hyup Og ◽  
Catherine J. Murphy

Double-network hydrogels have attracted much attention because of their superior mechanical properties, which are more similar to rubbers and soft tissues than classic hydrogels.


2017 ◽  
Vol 135 (9) ◽  
pp. 45925 ◽  
Author(s):  
Jae Sang Lee ◽  
Ho Seok Park ◽  
Young Jun Kim ◽  
Ji-Heung Kim

2014 ◽  
Vol 507 ◽  
pp. 415-420 ◽  
Author(s):  
Juan He ◽  
Cong Mi Cheng ◽  
Da Gen Su ◽  
Ming Feng Zhong

The germination and growth of mycelium are slightly affected by the addition of less than 5%sbrlatex. The latex is distributed in the culture medium to wrap them and fill in the void so that the culture medium can be tightly bonded together, and the mycelium is bonded to the latex, forming a double network. An increased specific strength of the composite would be expected in this case. Silane coupling agent seems to have no effect on mycelial growth, but it can improve the bond between latex and culture medium so that the specific strength of the composite is improved.


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