scholarly journals Design of Smart Oligo(ethylene glycol)-Based Biocompatible Hybrid Microgels Loaded with Magnetic Nanoparticles

2014 ◽  
Vol 36 (1) ◽  
pp. 79-83 ◽  
Author(s):  
Mohamed Boularas ◽  
Emilie Gombart ◽  
Jean-François Tranchant ◽  
Laurent Billon ◽  
Maud Save
Keyword(s):  
Magnetic Nanoparticles ◽  
Ethylene Glycol ◽  
Hybrid Microgels

scholarly journals Dual stimuli-responsive oligo(ethylene glycol)-based microgels: insight into the role of internal structure in volume phase transitions and loading of magnetic nanoparticles to design stable thermoresponsive hybrid microgels

2016 ◽  
Vol 7 (2) ◽  
pp. 350-363 ◽  
Author(s):  
Mohamed Boularas ◽  
Elise Deniau-Lejeune ◽  
Valérie Alard ◽  
Jean-François Tranchant ◽  
Laurent Billon ◽  
...  
Keyword(s):  
Phase Transitions ◽  
Magnetic Nanoparticles ◽  
Ethylene Glycol ◽  
Internal Structure ◽  
Stimuli Responsive ◽  
Volume Phase ◽  
Insight Into ◽  
Hybrid Microgels

Design of multi-responsive biocompatible P(MEO2MA-co-OEGMA-co-MAA) microgels and their hybrid magnetic couterparts.

Fe3O4 nanoparticles functionalized with poly(ethylene glycol) for the selective separation and enrichment of Au(iii)

2020 ◽  
Vol 44 (4) ◽  
pp. 1313-1319
Author(s):  
Xu Yang ◽  
Kunhao Yang ◽  
Li Wu ◽  
Jingkui Yang ◽  
Yujian He
Keyword(s):  
Aqueous Solution ◽  
Magnetic Nanoparticles ◽  
Ethylene Glycol ◽  
Fe3o4 Nanoparticles ◽  
Selective Separation ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Mechanism of Fe3O4@CPTES@PEG magnetic nanoparticles for selectively adsorbing Au(iii) from aqueous solution at pH = 1.0.

“Design of Poly(ethylene glycol)-Polycaprolactone Diblock Micelles with RGD Targeting Ligands and Embedded Iron Oxide Nanoparticles for Thermally-activated Release”

2012 ◽  
Vol 1416 ◽  
Author(s):  
Christopher S. Brazel ◽  
James B. Bennett ◽  
Amanda L. Glover ◽  
Jacqueline A. Nikles ◽  
Maaike Everts ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Melting Transition ◽  
Release Mechanism ◽  
Poly Ethylene Glycol ◽  
Rgd Peptides ◽  
Thermally Activated ◽  
Poly Ethylene

ABSTRACTA thermally-activated micelle consisting of a crystallizable poly(caprolactone), PCL, core and a poly(ethylene glycol), PEG, corona was developed to contain magnetic nanoparticles and anti-cancer agent doxorubicin as well as display a targeting RGD peptide. This system has the potential to target cancer cells, deliver combination hyperthermia and chemotherapy, and offer magnetic resonance imaging contrast. The micelles self-assemble in aqueous solutions and form a crystalline core with a melting transition ranging from 40 to 50 °C, depending on the length of the PCL blocks, with dynamic light scattering showing micelle sizes typically ranging from 20 to 100 nm, depending on block lengths and added drug or nanoparticles. The micelles become unstable as they are heated above their melting point, creating a thermally-activated drug release mechanism. By adding magnetite (Fe3O4) nanoparticles into the PCL core, the micelles can be heated using an externally applied AC magnetic field to induce hyperthermia in combination with the thermally-activated drug release. The polymers and magnetic nanoparticles (MNPs) were synthesized and characterized in our laboratories. The melting transitions of the PCL micelle cores were investigated using microcalorimetry. The heating of nanoparticles and magnetomicelles was conducted using a custom-built hyperthermia coil capable of generating fields of several hundred Oersteds at frequencies ranging from 50 to 450 kHz. Heating of MNPs was maximized at high field intensities. RGD peptides were attached to the PEG corona using maleimide chemistry, and the ability of the RGD-derivatized micelles to target integrin-expressing cells was investigated using fluorescent dye PKH26 to identify the localization of micelles in cultured human kidney (293) cells in vitro. The crystallizable (and meltable) cores in these micelles were designed to overcome drug leakage common in liposome systems and release the drug on demand after a period of time for localization to integrin receptors.

Ethylene Glycol-Protected Magnetic Nanoparticles for a Multiplexed Immunoassay in Human Plasma

Small ◽  
2006 ◽  
Vol 2 (4) ◽  
pp. 485-489 ◽  
Author(s):  
Po-Chiao Lin ◽  
Po-Hung Chou ◽  
Shu-Hua Chen ◽  
Hsin-Kai Liao ◽  
Kai-Yi Wang ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Ethylene Glycol ◽  
Human Plasma ◽  
Multiplexed Immunoassay

scholarly journals Synthesis and Evaluation of Magnetic Nanoparticles for Biomedical Applications

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Nydeia W. Bolden ◽  
Vijaya K. Rangari ◽  
Shaik Jeelani ◽  
Seyhan Boyoglu ◽  
Shree R. Singh
Keyword(s):  
Mössbauer Spectroscopy ◽  
Iron Oxide ◽  
Magnetic Nanoparticles ◽  
Ethylene Glycol ◽  
Mossbauer Spectroscopy ◽  
Iron Pentacarbonyl ◽  
Poly Vinyl Alcohol ◽  
Sonochemical Method ◽  
Power Ultrasound ◽  
Mößbauer Spectroscopy

In this study, iron oxide (IO) nanoparticles from various precursors have been synthesized using sonochemical method and characterized for their structural variability and toxicity. The iron oxide (IO) precursor solutions were prepared from iron acetate (IA), iron pentacarbonyl (IP), decalin, PEG (poly(ethylene glycol)), EG (ethylene glycol), PVA (poly(vinyl alcohol)), β-cyclodextrin (CD), and distilled water. These precursor solutions were irradiated with high power ultrasound for 3 hours and heat treated as needed. These as-prepared iron oxide nanoparticles were characterized using X-ray diffraction (XRD), Mössbauer spectroscopy, transmission electron microscopy (TEM), and magnetization measurements. XRD results show that all the particles are highly crystalline in nature and the particles sizes measured from TEM are approximately 5–20 nm. The maximum magnetization was observed for IO-IP at approximately 60.17 emu/g and the minimum was approximately 30.56 emu/g for IO-IA. These results confirm that the particles are superparamagnetic (SPM) in nature. Mössbauer spectroscopy verified the magnetic nanoparticles are purely Fe3O4 and particles sizes varied by the nature of the precursor and coatings.

Cross-linked magnetic nanoparticles from poly(ethylene glycol) and dodecyl grafted poly(succinimide) as magnetic resonance probes

2011 ◽  
Vol 47 (46) ◽  
pp. 12518 ◽  
Author(s):  
Hee-Man Yang ◽  
Chan Woo Park ◽  
Sujin Lim ◽  
Sung-Il Park ◽  
Bong Hyun Chung ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Magnetic Resonance ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene
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