A Reversible Multi-Stimuli-Responsive Fluorescence Probe and the Design for Combinational Logic Gate Operations

2013 ◽  
Vol 35 (3) ◽  
pp. 303-308 ◽  
Author(s):  
Hongyan Xia ◽  
Yangyang Xu ◽  
Guang Yang ◽  
Hao Jiang ◽  
Gang Zou ◽  
...  
2018 ◽  
Vol 27 (12) ◽  
pp. 1850184 ◽  
Author(s):  
Heranmoy Maity ◽  
Arijit Kumar Barik ◽  
Arindam Biswas ◽  
Anup Kumar Bhattacharjee ◽  
Anita Pal

In this paper, we have proposed a new reversible logic gate (NG) and also the quantum cost (QC), garbage outputs, delay optimized reversible combinational logic circuits such as four bit 2’s complement code converter circuit, BCD to Excess-3 code converter using reversible logic gate. The proposed NG is used to design a four bit 2’s complement code converter circuit, BCD to Excess-3 code converter and realization of different logic functions such as NOT, AND, NAND, OR, NOR, XOR, NXOR. The proposed (new reversible logic) gate is represented by quantum implementation. The proposed work is verified by Xilinx-ISE simulator software and others logic circuits are also verified. The QC of proposed gate is 5. The QC of four bit 2’s complement code converter and BCD to Excess-3 code converter are 11 and 14 which are better with respect to previous reported results.


Nanomaterials ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 128
Author(s):  
Lei Jia ◽  
Zhitao Xu ◽  
Rujie Chen ◽  
Xiangzhen Chen ◽  
Jun Xu

Tetracycline (TC) and oxytetracycline (OTC) are the most widely used broad-spectrum antimicrobial agents in tetracycline drugs, and their structures and properties are very similar, so it is a great challenge to distinguish and detect these two antibiotics with a single probe at the same time. Herein, a dual-channel fluorescence probe (SiCDs@mMIPs-cit-Eu) was developed by integrating two independent reaction sites with SiCDs-doped mesoporous silica molecular imprinting group and europium complex group into a nanomaterial. The synergistic influence of inner filter effect and “antenna effect” can be guaranteed to solve the distinction between TC and OTC. Moreover, this novel strategy can also sequentially detect TC and OTC in buffer solution and real samples with high sensitivity and selectivity. This method revealed good responses to TC and OTC ranging from 0 to 5.5 μM with a detection limit of 5 and 16 nM, respectively. Combined with the smartphone color-scanning application, the portable and cheap paper-based sensor was designed to realize the multi-color visual on-site detection of TC and OTC. In addition, the logic gate device was constructed according to the fluorescence color change of the probe for TC and OTC, which provided the application possibility for the intelligent detection of the probe.


Micromachines ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 713
Author(s):  
Yuefeng Gao ◽  
Sai Xu ◽  
Zhijian Liu ◽  
Kezhen Yu ◽  
Xinxiang Pan

It is urgent that a convenient and sensitive technique of detecting Hg2+ be developed because of its toxicity. Conventional fluorescence analysis works with a single fluorescence probe, and it often suffers from signal fluctuations which are influenced by external factors. In this research, a novel dual-emission probe assembled through utilizing CdTe quantum dots (QDs) and rhodamine B was designed to detect Hg2+ visually. Only the emission of CdTe QDs was quenched after adding Hg2+ in the dual-emission probe, which caused an intensity ratio change of the two different emission wavelengths and hence facilitated the visual detection of Hg2+. Compared to single emission QDs-based probe, a better linear relationship was shown between the variation of fluorescence intensity and the concentration of Hg2+, and the limit of detection (LOD) was found to be11.4 nM in the range of 0–2.6 μM. Interestingly, the intensity of the probe containing Hg2+ could be recovered in presence of glutathione (GSH) due to the stronger binding affinity of Hg2+ towards GSH than that towards CdTe QDs. Based on this phenomenon, an IMPLICATION logic gate using Hg2+/GSH as inputs and the fluorescence signal of QDs as an output was constructed.


2019 ◽  
Vol 55 (13) ◽  
pp. 1959-1962 ◽  
Author(s):  
Ayaka Banno ◽  
Sayuri Higashi ◽  
Aya Shibata ◽  
Masato Ikeda

A stimuli-responsive DNAzyme capable of exhibiting Boolean logic-gate responses is newly constructed.


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