scholarly journals Single Macromolecule Diffusion in Confined Environments

2011 ◽  
Vol 32 (18) ◽  
pp. 1411-1418 ◽  
Author(s):  
Matthew Mears ◽  
Drew S. Tarmey ◽  
Mark Geoghegan
Keyword(s):  
Single Macromolecule

Highly uniform self-assembled microspheres from single macromolecule self-recognition for enhanced cancer immunotherapy

2020 ◽  
Vol 56 (64) ◽  
pp. 9190-9193
Author(s):  
Xin Shen ◽  
Zhenxia Zhou ◽  
Dongmei Qi ◽  
Yanchao Li ◽  
Zhiying Zeng ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Immunotherapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Local Drug Delivery ◽  
Self Recognition ◽  
Self Assembled ◽  
Local Drug Delivery System ◽  
Highly Uniform ◽  
Single Macromolecule

Self-assembled highly uniform microspheres has been developed as a local drug delivery system for effective synergistic immunotherapy.

Submicron optical sources for single macromolecule detection

1993 ◽  
Author(s):  
Robert J. G. Carr ◽  
Sumaia Al-Shukri ◽  
Elaine A. Perkins ◽  
Thierry Rodard ◽  
Tony Atkinson
Keyword(s):  
Single Macromolecule

Adsorption of Copolymer Chains at Liquid-Liquid Interfaces: The Effect of Sequence Distribution

1991 ◽  
Vol 248 ◽  
Author(s):  
C. Yeung ◽  
Anna C. Balazs ◽  
David Jasnow
Keyword(s):  
Molecular Dynamics ◽  
Free Energy ◽  
Random Copolymer ◽  
Immiscible Fluids ◽  
Design Criteria ◽  
Liquid Interfaces ◽  
Sequence Distribution ◽  
Emulsion Stabilization ◽  
Dynamics Simulations ◽  
Single Macromolecule

The presence of copolymers at an interface between two immiscible fluids is crucial to such processes as emulsion stabilization and microemulsion formation [1]. Recently Marques and Joanny [2] and Garel et al. [3] have studied the behavior of a random copolymer at a liquid-liquid interface. However, the arrangement or sequence distribution of the monomers in a copolymer can vary widely from random to blocky or purely alternating. In this paper, we use both analytic arguments and molecular dynamics simulations to determine how the sequence distribution affects the adsorption and conformation of a single macromolecule at the boundary between two immiscible fluids [4]. In particular, we derive an expression for the free energy of a copolymer at the interface and compare the resulting predictions with the outcome of the simulations. Our findings yield design criteria for fabricating polymers that display the desired interfacial properties.

Precise Ratiometric Control of Dual Drugs through a Single Macromolecule for Combination Therapy

2015 ◽  
Vol 12 (7) ◽  
pp. 2318-2327 ◽  
Author(s):  
Shiying Luo ◽  
Ying Gu ◽  
Yuannian Zhang ◽  
Pei Guo ◽  
Jean Felix Mukerabigwi ◽  
...  
Keyword(s):  
Combination Therapy ◽  
Single Macromolecule
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