Novel Amphiphilic Degradable Poly(ɛ-caprolactone)-graft-poly(4-vinyl pyridine), Poly(ɛ-caprolactone)-graft-poly(dimethylaminoethyl methacrylate) and Water-Soluble Derivatives

2008 ◽  
Vol 29 (9) ◽  
pp. 743-750 ◽  
Author(s):  
Benjamin Nottelet ◽  
Michel Vert ◽  
Jean Coudane
Keyword(s):  
Water Soluble ◽  
Dimethylaminoethyl Methacrylate ◽  
Vinyl Pyridine

scholarly journals Thermoresponsive Poly(N-Isopropylacrylamide-co-Dimethylaminoethyl Methacrylate) Microgel Aqueous Dispersions with Potential Antimicrobial Properties

Polymers ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 606 ◽  
Author(s):  
Coro Echeverría ◽  
Alejandro Aragón-Gutiérrez ◽  
Marta Fernández-García ◽  
Alexandra Muñoz-Bonilla ◽  
Daniel López
Keyword(s):  
Antimicrobial Activity ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Viscoelastic Behavior ◽  
Water Soluble ◽  
Alkylation Reaction ◽  
Aqueous Dispersions ◽  
Dimethylaminoethyl Methacrylate ◽  
Preliminary Study ◽  
Potential Antimicrobial Activity

The work herein describes the preparation of thermoresponsive microgels with potential antimicrobial properties. Most of the work performed so far regarding microgels with antimicrobial activity, deals with the ability of microgels to carry and release antibiotics or antimicrobial agents (antimicrobial peptides). The originality of this work lies in the possibility of developing intrinsic antimicrobial microgels by copolymerization of the well-known thermoresponsive monomer, N-isopropylacrylamide (NIPAM) with dimethylaminoethyl methacrylate (DMAEMA), a water-soluble monomer, to form microgels via precipitation polymerization (radical polymerization). Due to the presence of a tertiary amine in the DMAEMA comonomer, microgels can be modified by N-alkylation reaction with methyl and butyl iodide. This quaternization confers positive charges to the microgel surfaces and thus the potential antimicrobial activity. The effect of DMAEMA content and its quaternization with both, methyl and butyl iodide is evaluated in terms of thermal and surface charge properties, as well as in the microgel size and viscoelastic behavior. Finally, a preliminary study of the antimicrobial activity against different microorganisms is also performed in terms of minimum inhibitory concentration (MIC). From this study we determined that in contrast with butylated microgels, methylated ones show potential antimicrobial activity and good physical properties besides of maintaining microgel thermo-responsiveness.

Novel water-soluble block copolymers of dimethylaminoethyl methacrylate and dihydroxypropyl methacrylate

1996 ◽  
Vol 197 (8) ◽  
pp. 2553-2564 ◽  
Author(s):  
Nynke G. Hoogeveen ◽  
Martien A. Cohen Stuart ◽  
Gerard J. Fleer ◽  
Willy Frank ◽  
Manfred Arnold
Keyword(s):  
Block Copolymers ◽  
Water Soluble ◽  
Dimethylaminoethyl Methacrylate

A Water-Soluble pH-Responsive Molecular Brush of Poly(N,N-dimethylaminoethyl methacrylate) Grafted Polythiophene

2008 ◽  
Vol 41 (19) ◽  
pp. 6993-7002 ◽  
Author(s):  
Mingfeng Wang ◽  
Shan Zou ◽  
Gerald Guerin ◽  
Lei Shen ◽  
Kangqing Deng ◽  
...  
Keyword(s):  
Water Soluble ◽  
Ph Responsive ◽  
Dimethylaminoethyl Methacrylate

A water-soluble CO2-triggered viscosity-responsive copolymer ofN,N-dimethylaminoethyl methacrylate and acrylamide

2014 ◽  
Vol 131 (19) ◽  
pp. n/a-n/a ◽  
Author(s):  
Hongsheng Lu ◽  
Jifeng Jiang ◽  
Zhiyu Huang ◽  
Shanshan Dai
Keyword(s):  
Water Soluble ◽  
Dimethylaminoethyl Methacrylate

Water-soluble triply-responsive homopolymers of N,N -dimethylaminoethyl methacrylate with a terminal azobenzene moiety

2010 ◽  
Vol 48 (12) ◽  
pp. 2564-2570 ◽  
Author(s):  
Xinde Tang ◽  
Xiaochao Liang ◽  
Longcheng Gao ◽  
Xinghe Fan ◽  
Qifeng Zhou
Keyword(s):  
Water Soluble ◽  
Dimethylaminoethyl Methacrylate ◽  
Azobenzene Moiety

A Resorcinol-Formaldehyde Resin as an Embedding Material for Electron Microscopy of Membranes

1969 ◽  
Vol 27 ◽  
pp. 328-329 ◽  
Author(s):  
J. G. Robertson ◽  
D. F. Parsons
Keyword(s):  
Electron Microscopy ◽  
Osmium Tetroxide ◽  
Neutral Lipids ◽  
Lipid Extraction ◽  
Water Soluble ◽  
Formaldehyde Resin ◽  
Electron Microscope Autoradiography ◽  
Resorcinol Formaldehyde ◽  
Major Disadvantage ◽  
Cell Organization

The extraction of lipids from tissues during fixation and embedding for electron microscopy is widely recognized as a source of possible artifact, especially at the membrane level of cell organization. Lipid extraction is also a major disadvantage in electron microscope autoradiography of radioactive lipids, as in studies of the uptake of radioactive fatty acids by intestinal slices. Retention of lipids by fixation with osmium tetroxide is generally limited to glycolipids, phospholipids and highly unsaturated neutral lipids. Saturated neutral lipids and sterols tend to be easily extracted by organic dehydrating reagents prior to embedding. Retention of the more saturated lipids in embedded tissue might be achieved by developing new cross-linking reagents, by the use of highly water soluble embedding materials or by working at very low temperatures.

Ferritin Labeled Antibody Staining of Thin Sections

1969 ◽  
Vol 27 ◽  
pp. 420-421
Author(s):  
J. D. McLean ◽  
S. J. Singer
Keyword(s):  
Biological Material ◽  
Water Soluble ◽  
Thin Sections ◽  
Antibody Staining ◽  
Thin Sectioning ◽  
Ultrathin Sections

The successful application of ferritin labeled antibodies (F-A) to ultrathin sections of biological material has been hampered by two main difficulties. Firstly the normally used procedures for the preparation of material for thin sectioning often result in a loss of antigenicity. Secondly the polymers employed for embedding may non-specifically absorb the F-A. Our earlier use of cross-linked polyampholytes as embedding media partially overcame these problems. However the water-soluble monomers used for this method still extract many lipids from the material.

The Effect of Benzene on Bluegill Olfactory Lamellae

1985 ◽  
Vol 43 ◽  
pp. 574-575
Author(s):  
D.R. Mattie ◽  
J.W. Fisher
Keyword(s):  
Surface Morphology ◽  
Soluble Fraction ◽  
Lepomis Macrochirus ◽  
Sublethal Concentration ◽  
Water Soluble ◽  
Major Constituent ◽  
Jet Fuels ◽  
Aquatic Biota ◽  
Normal Surface ◽  
Cacodylate Buffer

Jet fuels such as JP-4 can be introduced into the environment and come in contact with aquatic biota in several ways. Studies in this laboratory have demonstrated JP-4 toxicity to fish. Benzene is the major constituent of the water soluble fraction of JP-4. The normal surface morphology of bluegill olfactory lamellae was examined in conjunction with electrophysiology experiments. There was no information regarding the ultrastructural and physiological responses of the olfactory epithelium of bluegills to acute benzene exposure.The purpose of this investigation was to determine the effects of benzene on the surface morphology of the nasal rosettes of the bluegill sunfish (Lepomis macrochirus). Bluegills were exposed to a sublethal concentration of 7.7±0.2ppm (+S.E.M.) benzene for five, ten or fourteen days. Nasal rosettes were fixed in 2.5% glutaraldehyde and 2.0% paraformaldehyde in 0.1M cacodylate buffer (pH 7.4) containing 1.25mM calcium chloride. Specimens were processed for scanning electron microscopy.

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