scholarly journals Efficient Polymer-Polymer Conjugation via Thiol-ene Click Reaction

2017 ◽  
Vol 218 (18) ◽  
pp. 1700073 ◽  
Author(s):  
Benjamin D. Fairbanks ◽  
Dillon M. Love ◽  
Christopher N. Bowman
Keyword(s):  
Click Reaction ◽  
Polymer Conjugation

Double click reaction strategies for polymer conjugation and post-functionalization of polymers

2012 ◽  
Vol 3 (4) ◽  
pp. 825-835 ◽  
Author(s):  
Hakan Durmaz ◽  
Amitav Sanyal ◽  
Gurkan Hizal ◽  
Umit Tunca
Keyword(s):  
Click Reaction ◽  
Functionalization Of Polymers ◽  
Polymer Conjugation ◽  
Post Functionalization

The power of one-pot: a hexa-component system containing π–π stacking, Ugi reaction and RAFT polymerization for simple polymer conjugation on carbon nanotubes

2015 ◽  
Vol 6 (4) ◽  
pp. 509-513 ◽  
Author(s):  
Bin Yang ◽  
Yuan Zhao ◽  
Xu Ren ◽  
Xiaoyong Zhang ◽  
Changkui Fu ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Click Reaction ◽  
Raft Polymerization ◽  
Ugi Reaction ◽  
Polymer Modification ◽  
One Pot ◽  
Component System ◽  
Π Stacking ◽  
Polymer Conjugation

Ugi reaction has been recognized as a multicomponent click reaction to construct a hexa-component one-pot system with π–π stacking and RAFT polymerization for the simple (co)polymer modification of CNT surfaces.

Stabilization of Proteins by Polymer Conjugation via ATRP

2008 ◽  
Author(s):  
Jason Berberich ◽  
Lance Mabus ◽  
Virginia Depp ◽  
Bhalchandra Lele
Keyword(s):  
Polymer Conjugation

Synthetic Routes for 1,4-disubstituted 1,2,3-triazoles: A Review

2019 ◽  
Vol 23 (8) ◽  
pp. 860-900 ◽  
Author(s):  
Chander P. Kaushik ◽  
Jyoti Sangwan ◽  
Raj Luxmi ◽  
Krishan Kumar ◽  
Ashima Pahwa
Keyword(s):  
Solid Phase ◽  
Click Reaction ◽  
Biological Activities ◽  
Triazole Ring ◽  
Copper Catalysts ◽  
Biologically Active ◽  
Pharmaceutical Chemistry ◽  
Biological Targets ◽  
Synthetic Routes ◽  
High Yields

N-Heterocyclic compounds like 1,2,3-triazoles serve as a key scaffolds among organic compounds having diverse applications in the field of drug discovery, bioconjugation, material science, liquid crystals, pharmaceutical chemistry and solid phase organic synthesis. Various drugs containing 1,2,3-triazole ring which are commonly available in market includes Rufinamide, Cefatrizine, Tazobactam etc., Stability to acidic/basic hydrolysis along with significant dipole moment support triazole moiety for appreciable participation in hydrogen bonding and dipole-dipole interactions with biological targets. Huisgen 1,3-dipolar azide-alkyne cycloaddition culminate into a mixture of 1,4 and 1,5- disubstituted 1,2,3-triazoles. In 2001, Sharpless and Meldal came across with a copper(I) catalyzed regioselective synthesis of 1,4-disubstituted 1,2,3-triazoles by cycloaddition between azides and terminal alkynes. This azide-alkyne cycloaddition has been labelled as a one of the important key click reaction. Click synthesis describes chemical reactions that are simple to perform, gives high selectivity, wide in scope, fast reaction rate and high yields. Click reactions are not single specific reaction, but serve as a pathway for construction of simple to complex molecules from a variety of starting materials. In the last few decades, 1,2,3-triazoles attracted attention of researchers all over the world because of their broad spectrum of biological activities. Keeping in view the biological importance of 1,2,3-triazole, in this review we focus on the various synthetic routes for the syntheisis of 1,4-disubstituted 1,2,3-triazoles. This review involves various synthetic protocols which involves copper and non-copper catalysts, different solvents as well as substrates. It will boost synthetic chemists to explore new pathway for the development of newer biologically active 1,2,3-triazoles.

Green and Facile Synthesis of 1,4-Disubstituted 1,2,3-Triazoles via a Click Reaction of α-Bromo Ketones, [bmim]N3 and Terminal Acetylenes

2013 ◽  
Vol 10 (10) ◽  
pp. 738-743 ◽  
Author(s):  
Azadeh Fazeli ◽  
Hossein Oskooie ◽  
Yahya Beheshtiha ◽  
Majid Heravi ◽  
Hassan Valizadeh
Keyword(s):  
Click Reaction ◽  
Facile Synthesis ◽  
Terminal Acetylenes

scholarly journals Photo Click Reaction of Acylsilanes with Indoles

2021 ◽  
Author(s):  
Constantin Stuckhardt ◽  
Maren Wissing ◽  
Armido Studer
Keyword(s):  
Click Reaction
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