Complexation of Amino-Acid-Based Block Copolymers With Dual Thermoresponsive Properties and Water-Soluble Silsesquioxane Nanoparticles

2011 ◽  
Vol 212 (23) ◽  
pp. 2558-2572 ◽  
Author(s):  
Hideharu Mori ◽  
Shoko Saito ◽  
Kento Shoji
Keyword(s):  
Amino Acid ◽  
Block Copolymers ◽  
Water Soluble

Reversible heat coagulation of some water-soluble amino acid copolymers

1957 ◽  
Vol 23 (104) ◽  
pp. 843-849 ◽  
Author(s):  
Junzo Noguchi ◽  
Tadao Hayakawa ◽  
Mituo Ebata
Keyword(s):  
Amino Acid ◽  
Water Soluble

scholarly journals 145 Effects of titrated levels of water soluble zinc amino acid complex on growth performance of nursery pigs

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 82-83
Author(s):  
Pornpim Aparachita ◽  
Scott Carter ◽  
Afton Sawyer ◽  
Jared Harshman ◽  
Zach Rambo ◽  
...  
Keyword(s):  
Amino Acid ◽  
Growth Performance ◽  
Block Design ◽  
Water Soluble ◽  
Acid Complex ◽  
Zinc Intake ◽  
Nursery Pigs ◽  
Amino Acid Complex ◽  
Water Treatments ◽  
Soluble Zinc

Abstract Previously, we reported that supplementing a water soluble zinc via drinking water (0 to 80 mg/L) to nursery pigs improved ADG and G:F. To evaluate the efficacy of higher titrated levels of this water soluble zinc amino acid complex (ProPath®Zn LQ, Zinpro Corporation, Eden Prairie, MN) on growth performance, 280 crossbred pigs (5.5 kg BW; 19 d of age) were randomly allotted to four water treatments (7 pens/treatment; 10 pigs/pen). The water treatments were 0, 40, 80 and 160 mg Zn/L of water. Pigs were fed in 4 dietary phases with complex, nutrient-dense, corn-soybean meal-based diets: Phase 1 and 2 (2,500 and 1,750 mg Zn as ZnO/kg; d 1–7 and 7–14, respectively) and Phase 3 and 4 (200 mg Cu as CuSO4/kg; d 14–23 and 23–42, respectively). Pigs and feeders were weighed weekly to determine ADG, ADFI, and G:F. Water meters were used to record and calculate water disappearance and zinc intake. Data were analyzed as a randomized complete block design. Orthogonal polynomial contrasts were used to determine linear and curvilinear effects. Water and total zinc intake increased linearly (P < 0.001) with increasing water zinc concentration. From d 0–14 when high dietary zinc was fed, there were no differences (P > 0.10) in ADG, ADFI, or G:F. However, from d 14–42 when basal levels of zinc were fed, quadratic improvements in ADG (0.545, 0.561, 0.578, 0.546 kg; P < 0.05) and G:F (0.686, 0.706, 0.723, 0.702; P < 0.01) were observed with increasing zinc via water. Similarly for d 0–42, ADG (0.435, 0.440, 0.454; 0.434 kg; P = 0.07), G:F (0.726, 0.740, 0.763, 0.749; P = 0.05) and average ending wt (23.73, 23.97, 24.55, 23.70 kg; P = 0.07) improved quadratically with increasing zinc. In conclusion, supplementing ProPath®Zn LQ via water resulted in improvements in ADG and G:F for nursery pigs.

4-Aminopiperidine-4-carboxylic Acid:  A Cyclic α,α-Disubstituted Amino Acid for Preparation of Water-Soluble Highly Helical Peptides

1996 ◽  
Vol 61 (22) ◽  
pp. 7650-7651 ◽  
Author(s):  
Christopher L. Wysong ◽  
T. Scott Yokum ◽  
Guillermo A. Morales ◽  
Rebekah L. Gundry ◽  
Mark L. McLaughlin ◽  
...  
Keyword(s):  
Amino Acid ◽  
Carboxylic Acid ◽  
Water Soluble ◽  
Helical Peptides ◽  
Disubstituted Amino Acid

Design, synthesis, and partial characterization of water-soluble .beta.-sheets stabilized by a dibenzofuran-based amino acid

1993 ◽  
Vol 115 (9) ◽  
pp. 3790-3791 ◽  
Author(s):  
Humberto Diaz ◽  
Kwok Yin Tsang ◽  
Danny Choo ◽  
Jose R. Espina ◽  
Jeffery W. Kelly
Keyword(s):  
Amino Acid ◽  
Beta Sheets ◽  
Water Soluble ◽  
Partial Characterization ◽  
Design Synthesis

Design and synthesis of novel water-soluble amino acid derivatives of chlorin p6 ethers as photosensitizer

2019 ◽  
Vol 30 (1) ◽  
pp. 247-249 ◽  
Author(s):  
Xingjie Zhang ◽  
Zhi Meng ◽  
Zhiqiang Ma ◽  
Junhong Liu ◽  
Guiyan Han ◽  
...  
Keyword(s):  
Amino Acid ◽  
Water Soluble ◽  
Amino Acid Derivatives ◽  
Design And Synthesis ◽  
Derivatives Of ◽  
Chlorin P6

scholarly journals Preparation of Co-Amorphous Systems by Freeze-Drying

Pharmaceutics ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 941
Author(s):  
Melvin Wostry ◽  
Hanna Plappert ◽  
Holger Grohganz
Keyword(s):  
Amino Acid ◽  
Freeze Drying ◽  
Sodium Dodecyl ◽  
Solid Content ◽  
Water Soluble ◽  
Tween 20 ◽  
Scanning Calorimetry ◽  
Total Solid Content ◽  
Amorphous Systems ◽  
Freeze Dried

Freeze-drying was evaluated as a production technique for co-amorphous systems of a poorly water-soluble drug. Naproxen was freeze-dried together with arginine and lysine as co-former. To increase the solubility of naproxen in the starting solution, the applicability of five surfactants was investigated, namely sodium dodecyl sulfate, pluronic F-127, polyoxyethylene (40) stearate, tween 20 and TPGS 1000. The influence of the surfactant type, surfactant concentration and total solid content to be freeze-dried on the solid state of the sample was investigated. X-ray powder diffraction and differential scanning calorimetry showed that the majority of systems formed co-amorphous one-phase systems. However, at higher surfactant concentrations, and depending on the surfactant type, surfactant reflections were observed in the XRPD analysis upon production. Crystallization of both naproxen and amino acid occurred from some combinations under storage. In conclusion, freeze-drying was shown to be a feasible technique for the production of a selection of co-amorphous drug–amino acid formulations.

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