Modulation of Living Cell Behavior with Ultra‐Low Fouling Polymer Brush Interfaces

2020 ◽  
Vol 20 (3) ◽  
pp. 1900351 ◽  
Author(s):  
Ivana Víšová ◽  
Barbora Smolková ◽  
Mariia Uzhytchak ◽  
Markéta Vrabcová ◽  
Yulia Zhigunova ◽  
...  
Keyword(s):  
Living Cell ◽  
Polymer Brush ◽  
Cell Behavior

Modulation of Living Cell Behavior with Ultra‐Low Fouling Polymer Brush Interfaces

2020 ◽  
Vol 20 (3) ◽  
pp. 2070005 ◽  
Author(s):  
Ivana Víšová ◽  
Barbora Smolková ◽  
Mariia Uzhytchak ◽  
Markéta Vrabcová ◽  
Yulia Zhigunova ◽  
...  
Keyword(s):  
Living Cell ◽  
Polymer Brush ◽  
Cell Behavior

scholarly journals Polymer brush coatings regulating cell behavior: Passive interfaces turn into active

2014 ◽  
Vol 10 (6) ◽  
pp. 2367-2378 ◽  
Author(s):  
Lorenzo Moroni ◽  
Michel Klein Gunnewiek ◽  
Edmondo M. Benetti
Keyword(s):  
Polymer Brush ◽  
Cell Behavior

Binary polymer brush patterns from facile initiator stickiness for cell culturing

2019 ◽  
Vol 219 ◽  
pp. 189-202 ◽  
Author(s):  
Lina Chen ◽  
Peng Li ◽  
Xi Lu ◽  
Shutao Wang ◽  
Zijian Zheng
Keyword(s):  
Polymer Brush ◽  
Cell Behavior ◽  
Binary Polymer ◽  
Cell Culturing

A new initiator stickiness method is reported to fabricate binary polymer brush micropatterns, which are ideal platforms for studying cell behavior.

Solving the mechanisms responsible for organelle behavior in vivo by same-cell correlative light and electron microscopy

1992 ◽  
Vol 50 (1) ◽  
pp. 14-15
Author(s):  
Conly L. Rieder
Keyword(s):  
Electron Microscopy ◽  
Quantitative Analysis ◽  
Light Microscopy ◽  
Living Cell ◽  
Light And Electron Microscopy ◽  
Time Behavior ◽  
Dynamic Interactions ◽  
Positive Identification ◽  
Cellular Components

The behavior of many cellular components, and their dynamic interactions, can be characterized in the living cell with considerable spatial and temporal resolution by video-enhanced light microscopy (video-LM). Indeed, under the appropriate conditions video-LM can be used to determine the real-time behavior of organelles ≤ 25-nm in diameter (e.g., individual microtubules—see). However, when pushed to its limit the structures and components observed within the cell by video-LM cannot be resolved nor necessarily even identified, only detected. Positive identification and a quantitative analysis often requires the corresponding electron microcopy (EM).

Extracellular matrix: the gatekeeper of tumor angiogenesis

2019 ◽  
Vol 47 (5) ◽  
pp. 1543-1555 ◽  
Author(s):  
Maurizio Mongiat ◽  
Simone Buraschi ◽  
Eva Andreuzzi ◽  
Thomas Neill ◽  
Renato V. Iozzo
Keyword(s):  
Extracellular Matrix ◽  
Tumor Angiogenesis ◽  
Signaling Cascades ◽  
Cancer Growth ◽  
Cell Behavior ◽  
Metastatic Progression ◽  
Surface Receptors ◽  
The Matrix ◽  
Multiple Signaling

Abstract The extracellular matrix is a network of secreted macromolecules that provides a harmonious meshwork for the growth and homeostatic development of organisms. It conveys multiple signaling cascades affecting specific surface receptors that impact cell behavior. During cancer growth, this bioactive meshwork is remodeled and enriched in newly formed blood vessels, which provide nutrients and oxygen to the growing tumor cells. Remodeling of the tumor microenvironment leads to the formation of bioactive fragments that may have a distinct function from their parent molecules, and the balance among these factors directly influence cell viability and metastatic progression. Indeed, the matrix acts as a gatekeeper by regulating the access of cancer cells to nutrients. Here, we will critically evaluate the role of selected matrix constituents in regulating tumor angiogenesis and provide up-to-date information concerning their primary mechanisms of action.

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