A Silk Fibroin and Peptide Amphiphile-Based Co-Culture Model for Osteochondral Tissue Engineering

2016 ◽  
Vol 16 (8) ◽  
pp. 1212-1226 ◽  
Author(s):  
Soner Çakmak ◽  
Anıl S. Çakmak ◽  
David L. Kaplan ◽  
Menemşe Gümüşderelioğlu
Keyword(s):  
Tissue Engineering ◽  
Silk Fibroin ◽  
Peptide Amphiphile ◽  
Culture Model ◽  
Osteochondral Tissue ◽  
Osteochondral Tissue Engineering

scholarly journals Osteochondral Tissue Engineering In Vivo: A Comparative Study Using Layered Silk Fibroin Scaffolds from Mulberry and Nonmulberry Silkworms

PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e80004 ◽  
Author(s):  
Sushmita Saha ◽  
Banani Kundu ◽  
Jennifer Kirkham ◽  
David Wood ◽  
Subhas C. Kundu ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Comparative Study ◽  
Silk Fibroin ◽  
Osteochondral Tissue ◽  
Osteochondral Tissue Engineering

scholarly journals Silk Fibroin/Nano-CaP Bilayered Scaffolds for Osteochondral Tissue Engineering

2013 ◽  
Vol 587 ◽  
pp. 245-248 ◽  
Author(s):  
Le Ping Yan ◽  
Joaquim Miguel Oliveira ◽  
Ana L. Oliveira ◽  
Rui L. Reis
Keyword(s):  
Tissue Engineering ◽  
Simulated Body Fluid Solution ◽  
Single Layer ◽  
Bottom Layer ◽  
Apatite Crystal ◽  
Crystal Formation ◽  
Micro Computed Tomography ◽  
Computed Tomography Images ◽  
Osteochondral Tissue ◽  
Osteochondral Tissue Engineering

In this study, bilayered silk and silk/nanoCaP scaffolds were developed for osteochondral tissue engineering. Aqueous silk solution (16 wt.%) was used for preparation of the cartilage-like layer and, for generation of the silk/nanoCaP suspension and the bottom layer (CaP/Silk: 16 wt.%). The scaffolds were formed by using salt-leaching/lyophilization approach. The scanning electron microscopy revealed that the both layers presented porous structure and integrated well. Micro-computed tomography images confirmed that the CaP phase was only retained in the silk/nanoCaP layer. The hydration degree and mechanical properties of the bilayered scaffold were comparable to the ones of each single layer. The apatite crystal formation was limited to the silk/nanoCaP layer, when soaking the scaffold in a simulated body fluid solution, which is a must for the application of the developed scaffolds in OC tissue engineering.

scholarly journals Extrusion-based printing of poly(propylene fumarate) for osteochondral tissue engineering

2016 ◽  
Vol 4 ◽  
Author(s):  
Trachtenberg Jordan ◽  
Placone Jesse ◽  
Smith Brandon ◽  
Piard Charlotte ◽  
Fisher John ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Osteochondral Tissue ◽  
Poly Propylene ◽  
Osteochondral Tissue Engineering

Stem Cells in Osteochondral Tissue Engineering

2018 ◽  
pp. 359-372 ◽  
Author(s):  
Eleonora Pintus ◽  
Matteo Baldassarri ◽  
Luca Perazzo ◽  
Simone Natali ◽  
Diego Ghinelli ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Osteochondral Tissue ◽  
Osteochondral Tissue Engineering
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