Recent Strategies in Tissue Engineering for Guided Peripheral Nerve Regeneration

2016 ◽  
Vol 16 (4) ◽  
pp. 472-481 ◽  
Author(s):  
Kayla Belanger ◽  
Tony M. Dinis ◽  
Sami Taourirt ◽  
Guillaume Vidal ◽  
David L. Kaplan ◽  
...  
2015 ◽  
Vol 15 (6) ◽  
pp. 612-621 ◽  
Author(s):  
Lorena R. Lizarraga-Valderrama ◽  
Rinat Nigmatullin ◽  
Caroline Taylor ◽  
John W. Haycock ◽  
Frederik Claeyssens ◽  
...  

2021 ◽  
Vol 8 (4) ◽  
Author(s):  
Xiangyun Yao ◽  
Zhiwen Yan ◽  
Xu Wang ◽  
Huiquan Jiang ◽  
Yun Qian ◽  
...  

Abstract Graphene and its derivatives are fascinating materials for their extraordinary electrochemical and mechanical properties. In recent decades, many researchers explored their applications in tissue engineering and regenerative medicine. Reduced graphene oxide (rGO) possesses remarkable structural and functional resemblance to graphene, although some residual oxygen-containing groups and defects exist in the structure. Such structure holds great potential since the remnant-oxygenated groups can further be functionalized or modified. Moreover, oxygen-containing groups can improve the dispersion of rGO in organic or aqueous media. Therefore, it is preferable to utilize rGO in the production of composite materials. The rGO composite scaffolds provide favorable extracellular microenvironment and affect the cellular behavior of cultured cells in the peripheral nerve regeneration. On the one hand, rGO impacts on Schwann cells and neurons which are major components of peripheral nerves. On the other hand, rGO-incorporated composite scaffolds promote the neurogenic differentiation of several stem cells, including embryonic stem cells, mesenchymal stem cells, adipose-derived stem cells and neural stem cells. This review will briefly introduce the production and major properties of rGO, and its potential in modulating the cellular behaviors of specific stem cells. Finally, we present its emerging roles in the production of composite scaffolds for nerve tissue engineering.


2001 ◽  
Vol 44 (4) ◽  
pp. 419-426 ◽  
Author(s):  
Shenguo Wang ◽  
Jianwei Hou ◽  
Jianzhong Bei ◽  
Yongqiang Zhao

2007 ◽  
Vol 81A (3) ◽  
pp. 736-747 ◽  
Author(s):  
Stephanie Bruns ◽  
Yvonne Stark ◽  
Martin Wieland ◽  
Frank Stahl ◽  
Cornelia Kasper ◽  
...  

Author(s):  
Hongyu Liu ◽  
Yanan Zhao ◽  
Jun Tong ◽  
Xiaowen Shi ◽  
Yun Chen ◽  
...  

The development of peripheral nerve tissue engineering requires safe and reliable methodology to construct biodegradable conduits. Herein, a new type of chitosan-based nerve-guide hydrogel conduit (CNHC) with enhanced mechanical flexibility...


2021 ◽  
Author(s):  
Songyang Liu ◽  
Yijun Liu ◽  
Liping Zhou ◽  
Ci Li ◽  
Meng Zhang ◽  
...  

Peripheral nerve injury (PNI) remains an unresolved challenge in the medicine area. With the development of biomaterial science and tissue engineering, a variety of nerve conduits were widely applied in...


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