Targeted Imaging and Chemo-Phototherapy of Brain Cancer by a Multifunctional Drug Delivery System

2015 ◽  
Vol 15 (11) ◽  
pp. 1571-1585 ◽  
Author(s):  
Yongwei Hao ◽  
Lei Wang ◽  
Yalin Zhao ◽  
Dehui Meng ◽  
Dong Li ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Brain Cancer ◽  
Targeted Imaging

scholarly journals Nanogels as a Versatile Drug Delivery System for Brain Cancer

Gels ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. 63
Author(s):  
Brielle Stawicki ◽  
Tyler Schacher ◽  
Hyunah Cho
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Brain Cancer ◽  
Treatment Options ◽  
Three Dimensional ◽  
Patient Centered ◽  
Promising Tool ◽  
Systemic Drug Delivery ◽  
Systemic Drug

Chemotherapy and radiation remain as mainstays in the treatment of a variety of cancers globally, yet some therapies exhibit limited specificity and result in harsh side effects in patients. Brain tissue differs from other tissue due to restrictions from the blood–brain barrier, thus systemic treatment options are limited. The focus of this review is on nanogels as local and systemic drug delivery systems in the treatment of brain cancer. Nanogels are a unique local or systemic drug delivery system that is tailorable and consists of a three-dimensional polymeric network formed via physical or chemical assembly. For example, thermosensitive nanogels show promise in their ability to incorporate therapeutic agents in nano-structured matrices, be applied in the forms of sprays or sols to the area from which a tumor has been removed, form adhesive gels to fill the cavity and deliver treatment locally. Their usage does come with complications, such as handling, storage, chemical stability, and degradation. Despite these limitations, the current ongoing development of nanogels allows patient-centered treatment that can be considered as a promising tool for the management of brain cancer.

Hexosomes based on cholesterol and phosphatidylcholine: a new drug delivery system for curcumin release

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
AR Bilia ◽  
G Capecchi ◽  
MC Salvatici ◽  
B Isacchi ◽  
MC Bergonzi
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
New Drug
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