Poly(2-Hydroxyethyl Methacrylate)-b-Poly(L-Lysine) Cationic Hybrid Materials for Non-Viral Gene Delivery in NIH 3T3 Mouse Embryonic Fibroblasts

2014 ◽  
Vol 14 (9) ◽  
pp. 1239-1248 ◽  
Author(s):  
Renjith P. Johnson ◽  
Saji Uthaman ◽  
Johnson V. John ◽  
Min Seon Heo ◽  
In Kyu Park ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Hybrid Materials ◽  
Viral Gene ◽  
Hydroxyethyl Methacrylate ◽  
Mouse Embryonic Fibroblasts ◽  
Embryonic Fibroblasts ◽  
Viral Gene Delivery ◽  
Nih 3T3

Recent advances in the analysis full/empty capsid ratio and genome integrity of adeno-associated virus (AAV) gene delivery vectors

2020 ◽  
Vol 20 ◽  
Author(s):  
L. Hajba ◽  
A. Guttman
Keyword(s):  
Gene Delivery ◽  
High Efficiency ◽  
Analytical Techniques ◽  
Viral Gene ◽  
Adeno Associated Virus ◽  
Gene Delivery Vectors ◽  
Empty Capsid ◽  
Purification Methods ◽  
Viral Gene Delivery

: Adeno-associated virus (AAV) is one of the most promising viral gene delivery vectors with long-term gene expression and disease correction featuring high efficiency and excellent safety in human clinical trials. During the production of AAV vectors,there are several quality control (QC)parameters that should be rigorously monitored to comply with clini-cal safety and efficacy. This review gives a short summary of the most frequently used AVV production and purification methods,focusing on the analytical techniques applied to determine the full/empty capsid ratio and the integrity of the encapsidated therapeutic DNA of the products.

Non-viral gene delivery to atelectatic and ventilated lungs

2002 ◽  
Vol 73 (2) ◽  
pp. 432-437 ◽  
Author(s):  
Uz Stammberger ◽  
Aima N. Uduehi ◽  
Bartosz Kubisa ◽  
Thierry Roth ◽  
Ralph A. Schmid
Keyword(s):  
Gene Delivery ◽  
Viral Gene ◽  
Viral Gene Delivery

Modulating polymer chemistry to enhance non-viral gene delivery inside hydrogels with tunable matrix stiffness

Biomaterials ◽  
2013 ◽  
Vol 34 (37) ◽  
pp. 9657-9665 ◽  
Author(s):  
Michael Keeney ◽  
Sheila Onyiah ◽  
Zhe Zhang ◽  
Xinming Tong ◽  
Li-Hsin Han ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Polymer Chemistry ◽  
Viral Gene ◽  
Matrix Stiffness ◽  
Viral Gene Delivery

scholarly journals Non-viral gene delivery nanoparticles based on Poly(β-amino esters) for treatment of glioblastoma

Biomaterials ◽  
2011 ◽  
Vol 32 (23) ◽  
pp. 5402-5410 ◽  
Author(s):  
Stephany Y. Tzeng ◽  
Hugo Guerrero-Cázares ◽  
Elliott E. Martinez ◽  
Joel C. Sunshine ◽  
Alfredo Quiñones-Hinojosa ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Viral Gene ◽  
Amino Esters ◽  
Viral Gene Delivery
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