scholarly journals Influence of donor age on graft survival after liver transplantation-united network for organ sharing registry

1995 ◽  
Vol 1 (5) ◽  
pp. 311-319 ◽  
Author(s):  
Katherine M. Detre ◽  
Manuel Lombardero ◽  
Steven Belle ◽  
Kimberly Beringer ◽  
Timothy Breen ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Graft Survival ◽  
Donor Age ◽  
United Network

Both Alcoholic and Nonalcoholic Steatohepatitis Is an Emerging Indication for Liver Transplantation in the United States

2020 ◽  
Vol 04 (02) ◽  
pp. 223-234
Author(s):  
Danielle Fritze ◽  
Amandeep Singh ◽  
Eric Lawitz ◽  
Kris V. Kowdley ◽  
Glenn Halff ◽  
...  
Keyword(s):  
United States ◽  
Liver Transplantation ◽  
Graft Survival ◽  
Nonalcoholic Steatohepatitis ◽  
Multivariable Analysis ◽  
Deceased Donor ◽  
The United States ◽  
Hispanic Males ◽  
Patient And Graft Survival ◽  
United Network

Abstract Background Nonalcoholic steatohepatitis (NASH) and alcoholic liver disease (ALD) are now the most common indications for liver transplantation (LT) in the United States. A subset of patients have both alcoholic and nonalcoholic steatohepatitis (BASH). This study characterizes patients with BASH requiring LT and assesses changes in the prevalence of BASH as an indication for LT. Methods The United Network for Organ Sharing database was analyzed for all patients ≥ 18 years of age who received their first deceased donor LT from 2002 to 2016 for ALD, NASH, or BASH. Baseline demographics, clinical parameters, and LT outcomes were compared between groups. Results Since 2002, 85,448 patients underwent LT:15,327 had ALD, 9,971 had NASH, and 2,779 had BASH. The prevalence of BASH as an indication for LT increased from 0.5% in 2002 to 5% in 2016. Compared with patients with NASH, those with BASH were significantly more likely to be male (85.6 vs. 57%), younger (mean 56.4 vs. 58.6 years), and Hispanic (22.2 vs. 13.6%) (p < 0.001 for all). While indication for transplant was not significantly associated with transplant outcomes on multivariable analysis, patient and graft survival curves do differ significantly by indication for transplant, with worse outcomes for patients with BASH (patient survival at 5 years: NASH 78.1%, ALD 77.2%, BASH 73.5%, p = 0.013; graft survival at 5 years: NASH 75.3%, ALD 74.0%, BASH 70.8%, p = 0.046). Conclusions BASH is a rising indication for LT, especially for Hispanic males, due to the increasing prevalence of ALD and NASH in the United States.

Donor age affects fibrosis progression and graft survival after liver transplantation for hepatitis C1

2004 ◽  
Vol 77 (1) ◽  
pp. 84-92 ◽  
Author(s):  
Victor I. Machicao ◽  
Hugo Bonatti ◽  
Murli Krishna ◽  
Bashar A. Aqel ◽  
Frank J. Lukens ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Graft Survival ◽  
Donor Age ◽  
Fibrosis Progression

THE IMPACT OF DONOR AGE ON LIVER TRANSPLANTATION: INFLUENCE OF DONOR AGE ON EARLY LIVER FUNCTION AND ON SUBSEQUENT PATIENT AND GRAFT SURVIVAL

2001 ◽  
Vol 71 (12) ◽  
pp. 1765-1771 ◽  
Author(s):  
Juli Busquets ◽  
Xavier Xiol ◽  
Juan Figueras ◽  
Eduardo Jaurrieta ◽  
Jaume Torras ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Function ◽  
Graft Survival ◽  
Donor Age ◽  
The Impact ◽  
Subsequent Patient ◽  
Patient And Graft Survival

P884 DONOR/RECIPIENT GENDER MISMATCH MODIFIES THE IMPACT OF DONOR AGE ON GRAFT SURVIVAL FOLLOWING LIVER TRANSPLANTATION

2014 ◽  
Vol 60 (1) ◽  
pp. S368-S369
Author(s):  
D. Bitetto ◽  
S. Pecere ◽  
M. Gambato ◽  
A. Ferrarese ◽  
L. Pasulo ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Graft Survival ◽  
Donor Age ◽  
The Impact

scholarly journals Optimization of long-term graft survival after liver transplantation: the role of donor age

2011 ◽  
Vol 11 (Suppl 1) ◽  
pp. A25 ◽  
Author(s):  
Q Lai ◽  
F Melandro ◽  
G Spoletini ◽  
GB Levi Sandri ◽  
N Guglielmo ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Graft Survival ◽  
Donor Age

Advanced Donor Age Alone Does Not Affect Patient or Graft Survival after Liver Transplantation

2008 ◽  
Vol 207 (6) ◽  
pp. 847-852 ◽  
Author(s):  
Christopher D. Anderson ◽  
Neeta Vachharajani ◽  
Majella Doyle ◽  
Jeffrey A. Lowell ◽  
Jason R. Wellen ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Graft Survival ◽  
Donor Age
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