scholarly journals Rural‐Urban Differences in In‐Hospital Mortality Among Admissions for End‐Stage Liver Disease in the United States

2019 ◽  
Vol 25 (9) ◽  
pp. 1321-1332 ◽  
Author(s):  
Katherine H. Ross ◽  
Rachel E. Patzer ◽  
David Goldberg ◽  
Nicolas H. Osborne ◽  
Raymond J. Lynch
Keyword(s):  
United States ◽  
Liver Disease ◽  
Hospital Mortality ◽  
The United States ◽  
End Stage Liver Disease ◽  
End Stage

Liver Transplantation for the Gastroenterologist

2015 ◽  
Author(s):  
Andreea M. Catana ◽  
Michael P. Curry
Keyword(s):  
United States ◽  
Liver Transplantation ◽  
Liver Disease ◽  
Organ Procurement ◽  
The United States ◽  
Waiting Lists ◽  
Liver Graft ◽  
Term Survival ◽  
End Stage Liver Disease ◽  
End Stage

The first liver transplantation (LT) was performed in 1963, and currently more than 65,000 people in the United States are living with a transplanted liver. In 2012, the number of adults who registered on the LT waiting list decreased for the first time since 2002; 10,143 candidates were added compared with 10,359 in 2011. LT offers long-term survival for complications of end-stage liver disease and prolongs life in properly selected patients, but problems such as donor deficit, geographic disparities, and long waiting lists remain. This overview of LT for the gastroenterologist details the indications for LT and patient selection, evaluation, liver organ allocation, prioritization for transplantation, transplantation benefit by the Model for End-Stage Liver Disease (MELD), MELD limitations, sources of liver graft, strategies employed to decrease the donor deficit, complications, and outcomes. Figures include indications for LT in Europe and the United States, Organ Procurement and Transplantation Network regions in the United States, the number of transplants and size of active waiting lists, mortality by MELD, regional disparity, patient survival rates with and without hepatitis C virus, and unadjusted patient and graft survival. Tables list LT milestones, indications for LT, contraindications for LT, minimal listing criteria for LT, criteria for LT in acute liver failure, LT evaluation process, adult recipient listing status 1A, and early posttransplantation complications. This review contains 7 highly rendered figures, 8 tables, and 46 references. 

scholarly journals Delayed hepatocellular carcinoma model for end-stage liver disease exception score improves disparity in access to liver transplant in the United States

Hepatology ◽  
2015 ◽  
Vol 61 (5) ◽  
pp. 1643-1650 ◽  
Author(s):  
Julie K. Heimbach ◽  
Ryutaro Hirose ◽  
Peter G. Stock ◽  
David P. Schladt ◽  
Hui Xiong ◽  
...  
Keyword(s):  
United States ◽  
Hepatocellular Carcinoma ◽  
Liver Disease ◽  
Liver Transplant ◽  
The United States ◽  
End Stage Liver Disease ◽  
End Stage

General Surgery in Patients with End-Stage Organ Disease

2015 ◽  
Author(s):  
Amy R. Evenson ◽  
Ramanathan M. Seshadri ◽  
Jonathan P. Fryer
Keyword(s):  
United States ◽  
Liver Disease ◽  
Renal Disease ◽  
General Surgery ◽  
End Stage Renal Disease ◽  
The United States ◽  
Av Fistula ◽  
End Stage Liver Disease ◽  
Stage Renal Disease ◽  
End Stage

The number of patients with end-stage organ disease in the United States is substantial. Patients with end-stage organ disease are susceptible to all of the surgical problems seen in general surgical practice, with the added comorbidities associated with their organ failure. Hence, understanding of the principles of perioperative patient management is important as part of a general surgery practice. The chapter contains details on general and peripheral vascular surgical procedures, including dialysis access for patients with end-stage renal disease. Details on management of abdominal hernias, cholelithiasis, and disorders of the intestine in patients with end-stage liver disease are provided. Table 1 discusses the advantages and disadvantages of arteriovenous (AV) fistulas versus AV grafts. Table 2 describes “the rule of 6’s” for mature AV fistula. Table 3 has information on potential barriers to peritoneal dialysis. Table 4 is the Child-Pugh-Turcotte classification of severity of liver disease. Table 5 discusses the factors affecting the decision to operate and timing of operation in patients with end-stage liver disease. Figure 1 shows the increasing incidence of end-stage renal disease in the United States. Figure 2 is the five-stage classification system for chronic kidney disease. Figure 3 illustrates the various options for upper extremity AV fistula. This review contains 3 figures, 5 tables, and 68 references.

scholarly journals Factors that affect deceased donor liver transplantation rates in the United States in addition to the model for end‐stage liver disease score

2012 ◽  
Vol 18 (12) ◽  
pp. 1456-1463 ◽  
Author(s):  
Pratima Sharma ◽  
Douglas E. Schaubel ◽  
Emily E. Messersmith ◽  
Mary K. Guidinger ◽  
Robert M. Merion
Keyword(s):  
United States ◽  
Liver Transplantation ◽  
Liver Disease ◽  
Deceased Donor ◽  
The United States ◽  
Disease Score ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
End Stage Liver Disease ◽  
End Stage

scholarly journals A3 TREATMENT IN DISPROPORTIONATELY MINORITY HOSPITALS IS ASSOCIATED WITH AN INCREASED MORTALITY IN END STAGE LIVER DISEASE

2020 ◽  
Vol 3 (Supplement_1) ◽  
pp. 3-5
Author(s):  
A S Alotaibi ◽  
M Brahmania ◽  
O Mooney ◽  
B Rush
Keyword(s):  
Liver Disease ◽  
Mortality Rate ◽  
Hospital Mortality ◽  
Cohort Analysis ◽  
Ethnic Disparities ◽  
The United States ◽  
Multivariate Logistic Regression Model ◽  
End Stage Liver Disease ◽  
Patient Race ◽  
End Stage

Abstract Background Racial and ethnic disparities continue to remain a barrier in delivery of health care across the United States. Care for minority patients tends to be clustered into a small number of providers at minority hospitals, which has been associated with worse clinical outcomes in several conditions. However, the outcomes of treatment in end stage liver disease (ESLD) patients at predominately minority hospitals is unknown. Aims To evaluate in-hospital mortality rate among ESLD patients treated in minority hospitals compared to non-minority hospitals. Methods We utilized the Nationwide Inpatient Sample (NIS) to conduct a retrospective nationwide cohort analysis. All patients >18 years of age admitted with ESLD were included in the analysis. A multivariate logistic regression model was used to study the mortality rate among ESLD patients treated at minority hospitals compared to ESLD patients treated at non-minority hospitals. Results A total of 53,281,467 hospitalizations from the 2008–2014 NIS sample were analyzed. There were 163,470 patients with ESLD that met inclusion criteria. There were 10,178 (6.2%) and 31,226 (19.1%) ESLD patients treated at Black and Hispanic minority hospitals, respectively. In hospital mortality rate for all races were 8.0% and 8.1% in Black and Hispanic minority hospitals, respectively, compared to 7.3% in non-minority hospitals (p<0.01). On multivariate analysis, treatment of ESLD in Black and Hispanic minority hospitals were associated with a 11% (OR: 1.11; 95% CI: 1.03–1.20; p<0.01) and 22% (OR: 1.22; 95% CI: 1.09–1.37; p<0.01) increased odds of death, respectively, compared to treatment in a non-minority hospital regardless of patient race. Conclusions ESLD patient treated at minority hospital are faced with an increased mortality rate regardless of a patients race. The current study highlights a quality gap that needs improvement to effect overall survival among ESLD patients. Funding Agencies None

Palliative care access for hospitalized patients with end‐stage liver disease across the United States

Hepatology ◽  
2017 ◽  
Vol 66 (5) ◽  
pp. 1585-1591 ◽  
Author(s):  
Barret Rush ◽  
Keith R. Walley ◽  
Leo A. Celi ◽  
Neil Rajoriya ◽  
Mayur Brahmania
Keyword(s):  
United States ◽  
Palliative Care ◽  
Liver Disease ◽  
The United States ◽  
Hospitalized Patients ◽  
End Stage Liver Disease ◽  
Care Access ◽  
End Stage
Sign in / Sign up

Export Citation Format

Share Document