Predictive Value of Hepatic Venous Pressure Gradient for Graft Hemodynamics in Living Donor Liver Transplantation

2019 ◽  
Vol 25 (7) ◽  
pp. 1034-1042 ◽  
Author(s):  
Hajime Matsushima ◽  
Masato Fujiki ◽  
Kazunari Sasaki ◽  
Daniel M. Rotroff ◽  
Mark Sands ◽  
...  
2018 ◽  
Vol 24 (11) ◽  
pp. 1578-1588 ◽  
Author(s):  
Siyuan Yao ◽  
Toshimi Kaido ◽  
Ryuji Uozumi ◽  
Shintaro Yagi ◽  
Yosuke Miyachi ◽  
...  

2004 ◽  
Vol 11 (1) ◽  
pp. 68-75 ◽  
Author(s):  
Shintaro Yagi ◽  
Taku Iida ◽  
Kentaro Taniguchi ◽  
Tomohide Hori ◽  
Takashi Hamada ◽  
...  

2017 ◽  
Vol 7 (3) ◽  
pp. 235-246 ◽  
Author(s):  
Amol Vijay Kanetkar ◽  
Dinesh Balakrishnan ◽  
Sudhindran Sudhindran ◽  
Puneet Dhar ◽  
Unnikrishnan Gopalakrishnan ◽  
...  

2019 ◽  
Vol 24 ◽  
pp. 401-406 ◽  
Author(s):  
Ahmed H. Khalil ◽  
Mohammed Khattab ◽  
Karim A. Hosny ◽  
Mostafa Elshazly ◽  
Ayman Salah Eldin ◽  
...  

2021 ◽  
Vol 10 (15) ◽  
pp. 3401
Author(s):  
Chen-Fang Lee ◽  
Hao-Chien Hung ◽  
Wei-Chen Lee

Background: Diagnostic tests for early allograft dysfunction (EAD) after living donor liver transplantation (LDLT) vary widely. We aimed to evaluate the predictive value of rotational thromboelastometry (ROTEM)-derived parameters in EAD. Materials and Methods: A total of 121 patients were reviewed. The definition of EAD proposed by Olthoff et al. included the presence of any of the following at postoperative day 7: bilirubin level ≥ 10 mg/dL, INR ≥ 1.6, or serum AST or ALT levels > 2000 IU/L. All patients underwent ROTEM assay, which consisted of an extrinsically activated thromboelastometric test (EXTEM) before and 24 h after LDLT. Results: The 1-year/2-year OS were 68.%8/64.5% and 94.4%/90.8% for the EAD and non-EAD groups, respectively (p = 0.001). Two independent risks were identified for EAD, the postoperative clotting time (CT, p = 0.026) and time to maximum clot firmness (maximum clot firmness (MCF)-t, p = 0.009) on the EXTEM. CT yielded a specificity of 82.0% and negative predictive value of 83.0%, and MCF-t displayed a specificity of 76.4% and negative predictive value of 81.9% in diagnosing EAD. The use of the 24 h post-LDLT ROTEM increased the effectiveness of predicting overall survival (OS) compared to using the Olthoff’s EAD criteria alone (p < 0.001). Conclusion: We conclude that CT and MCF on EXTEM were independent predictors of EAD. The 24 h post-LDLT ROTEM can be used with conventional laboratory tests to diagnose EAD. It increases the effectiveness of predicting OS.


2019 ◽  
Vol 87 (March) ◽  
pp. 41-44
Author(s):  
AHMED H. KHALIL, M.D., M.R.C.S.; MOHAMMED KHATTAB, M.Sc. ◽  
KAREEM HOSNY, M.D. MOSTAFA EL-SHAZLY, M.D. ◽  
AYMAN SALAH ELDIN, M.D. ADEL HOSNY, M.D.

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