Not All Cellular Rejections Are the Same: Differences in Early and Late Hepatic Allograft Rejection

2019 ◽  
Vol 25 (3) ◽  
pp. 425-435 ◽  
Author(s):  
Caroline C. Jadlowiec ◽  
Paige E. Morgan ◽  
Avinash K. Nehra ◽  
Matthew A. Hathcock ◽  
Walter K. Kremers ◽  
...  
Keyword(s):  
Allograft Rejection ◽  
Hepatic Allograft

INFILTRATING CELL PHENOTYPES AND PATTERNS ASSOCIATED WITH HEPATIC ALLOGRAFT REJECTION OR ACCEPTANCE

1987 ◽  
Vol 43 (2) ◽  
pp. 169-172 ◽  
Author(s):  
JOHN A. WOLFE ◽  
JAMES BURCHETTE ◽  
FRED SANFILIPPO ◽  
R. RANDAL BOLLINGER ◽  
STUART J. KNECHTLE
Keyword(s):  
Allograft Rejection ◽  
Cell Phenotypes ◽  
Hepatic Allograft

scholarly journals Peroxynitrite formation during rat hepatic allograft rejection

Hepatology ◽  
1999 ◽  
Vol 29 (3) ◽  
pp. 777-784 ◽  
Author(s):  
Yasuo Yamaguchi ◽  
Kazutoshi Okabe ◽  
Fujio Matsumura ◽  
Eiji Akizuki ◽  
Teishi Matsuda ◽  
...  
Keyword(s):  
Allograft Rejection ◽  
Hepatic Allograft

Eosinophil cationic protein's role in human hepatic allograft rejection

Hepatology ◽  
1991 ◽  
Vol 13 (6) ◽  
pp. 1117-1125 ◽  
Author(s):  
Preston F. Foster ◽  
Achyut Bhattacharyya ◽  
Howard N. Sankary ◽  
James Coleman ◽  
Marilyn Ashmann ◽  
...  
Keyword(s):  
Allograft Rejection ◽  
Hepatic Allograft

AN ANALYSIS OF THE DETERMINANTS OF HEPATIC ALLOGRAFT REJECTION USING STEPWISE LOGISTIC REGRESSION

1989 ◽  
Vol 47 (1) ◽  
pp. 74-76 ◽  
Author(s):  
Howard Sankary ◽  
Preston Foster ◽  
Marquis Hart ◽  
Marilyn Ashmann ◽  
Daniel Schwartz ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Allograft Rejection ◽  
Stepwise Logistic Regression ◽  
Hepatic Allograft

Immunohistologic Pattern of the Portal T-Lymphocyte Infiltration in Hepatic Allograft Rejection

1989 ◽  
Vol 64 (5) ◽  
pp. 565-569 ◽  
Author(s):  
JAMES D. PERKINS ◽  
JORGE RAKELA ◽  
SYLVESTER STERIOFF ◽  
PETER M. BANKS ◽  
RUSSELL H. WIESNER ◽  
...  
Keyword(s):  
T Lymphocyte ◽  
Allograft Rejection ◽  
Lymphocyte Infiltration ◽  
Hepatic Allograft

Role of ICAM-1 in chronic hepatic allograft rejection in the rat

2002 ◽  
Vol 283 (1) ◽  
pp. G196-G203 ◽  
Author(s):  
John Wong ◽  
Paul Kubes ◽  
Yikun Zhang ◽  
Yang Li ◽  
Stefan J. Urbanski ◽  
...  
Keyword(s):  
Allograft Rejection ◽  
Leukocyte Adhesion ◽  
Leukocyte Recruitment ◽  
Intercellular Adhesion Molecule ◽  
Brown Norway ◽  
Intercellular Adhesion Molecule 1 ◽  
Cell Recruitment ◽  
Hepatic Allograft

The pathogenesis of hepatic allograft rejection remains unclear. We aimed to clarify the early role of intercellular adhesion molecule-1 (ICAM-1)-mediated cell recruitment in chronic hepatic rejection. Liver transplantation was performed from Lewis to Lewis rats (isograft controls) and from Lewis to Brown Norway rats (allograft rejection group). The allografted rats were treated with either ICAM-1 antisense oligonucleotides (10 mg · kg−1· day−1× 6 days ip) or a control preparation (either ICAM-1 missense oligonucleotide or normal saline). Hepatic leukocyte recruitment in vivo was studied on day 6 by using intravital microscopy. Liver histology, biochemistry, and survival rates were also examined. Leukocyte adhesion in terminal hepatic venules was significantly increased in the rejection group compared with isograft controls. Antisense ICAM-1 in the allografted group effectively reduced leukocyte adhesion. Histology and liver chemistry were less deranged in the antisense-treated groups compared with control-treated allografted rats. In the allograft groups, survival was significantly prolonged in the antisense-treated rats (42.3 ± 1.2 days) compared with the controls (25.2 ± 2.7 days). These results showed that early leukocyte recruitment in the hepatic microvasculature of rejecting allografts is ICAM-1 dependent and suggest that impacting on early cell recruitment can significantly ameliorate chronic rejection.

BILIARY INTERLEUKIN 6 LEVELS AS INDICATORS OF HEPATIC ALLOGRAFT REJECTION IN RATS

1992 ◽  
Vol 53 (6) ◽  
pp. 1195-1201 ◽  
Author(s):  
TAKESHI TONO ◽  
MORITO MONDEN ◽  
KAZUYUKI YOSHIZAKI ◽  
LUIS A. VALDIVIA ◽  
YOSHIAKI NAKANO ◽  
...  
Keyword(s):  
Interleukin 6 ◽  
Allograft Rejection ◽  
Hepatic Allograft

TACROLIMUS FOR PRIMARY TREATMENT OF STEROID-RESISTANT HEPATIC ALLOGRAFT REJECTION

1996 ◽  
Vol 61 (9) ◽  
pp. 1365-1369 ◽  
Author(s):  
J. Michael Millis ◽  
E. Steve Woodle ◽  
James B. Piper ◽  
David S. Bruce ◽  
Kenneth A. Newell ◽  
...  
Keyword(s):  
Allograft Rejection ◽  
Primary Treatment ◽  
Steroid Resistant ◽  
Hepatic Allograft
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