scholarly journals Use of serial assessment of disease severity and liver biopsy for indication for liver transplantation in pediatric Epstein-Barr virus-induced fulminant hepatic failure

2015 ◽  
Vol 21 (3) ◽  
pp. 362-368 ◽  
Author(s):  
Atsuko Nakazawa ◽  
Natsuko Nakano ◽  
Akinari Fukuda ◽  
Seisuke Sakamoto ◽  
Ken-Ichi Imadome ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Biopsy ◽  
Disease Severity ◽  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Demonstration of Epstein-Barr virus DNA in a previously healthy boy with fulminant hepatic failure

1986 ◽  
Vol 145 (1-2) ◽  
pp. 94-98 ◽  
Author(s):  
J. Deutsch ◽  
H. Wolf ◽  
H. Becker ◽  
B. Fuchs ◽  
U. Goriup ◽  
...  
Keyword(s):  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Identification of Epstein–Barr virus-infected CD27+ memory B-cells in liver or stem cell transplant patients

2011 ◽  
Vol 92 (11) ◽  
pp. 2590-2595 ◽  
Author(s):  
Yoshinori Ito ◽  
Shinji Kawabe ◽  
Seiji Kojima ◽  
Fumihiko Nakamura ◽  
Yukihiro Nishiyama ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Stem Cell ◽  
B Cells ◽  
Epstein Barr Virus ◽  
Peripheral Blood Lymphocytes ◽  
Haematopoietic Stem Cell ◽  
Cell Transplant ◽  
Barr Virus ◽  
Infected Cells ◽  
Epstein Barr

To analyse the phenotype of Epstein–Barr virus (EBV)-infected lymphocytes in EBV-associated infections, cells from eight haematopoietic stem cell/liver transplantation recipients with elevated EBV viral loads were examined by a novel quantitative assay designed to identify EBV-infected cells by using a flow cytometric detection of fluorescent in situ hybridization (FISH) assay. By this assay, 0.05–0.78 % of peripheral blood lymphocytes tested positive for EBV, and the EBV-infected cells were CD20+ B-cells in all eight patients. Of the CD20+ EBV-infected lymphocytes, 48–83 % of cells tested IgD positive and 49–100 % of cells tested CD27 positive. Additionally, the number of EBV-infected cells assayed by using FISH was significantly correlated with the EBV-DNA load, as determined by real-time PCR (r 2 = 0.88, P<0.0001). The FISH assay enabled us to characterize EBV-infected cells and perform a quantitative analysis in patients with EBV infection after stem cell/liver transplantation.

Epstein-Barr virus and persistent graft dysfunction after liver transplantation

Hepatology ◽  
1991 ◽  
Vol 14 (2) ◽  
pp. 282-286 ◽  
Author(s):  
Amadlo Telenti ◽  
Thomas F. Smith ◽  
Jurgen Ludwig ◽  
Michael R. Keating ◽  
Rund A. F. Krom ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Epstein Barr Virus ◽  
Graft Dysfunction ◽  
Barr Virus ◽  
Epstein Barr
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