Intrathecal morphine combined with intravenous patient-controlled analgesia is an effective and safe method for immediate postoperative pain control in live liver donors

2009 ◽  
Vol 15 (4) ◽  
pp. 381-389 ◽  
Author(s):  
Justin Sangwook Ko ◽  
Soo Joo Choi ◽  
Mi Sook Gwak ◽  
Gaab Soo Kim ◽  
Hyun Joo Ahn ◽  
...  
Keyword(s):  
Postoperative Pain ◽  
Pain Control ◽  
Intrathecal Morphine ◽  
Patient Controlled Analgesia ◽  
Postoperative Pain Control ◽  
Safe Method ◽  
Liver Donors

scholarly journals Is a Single Low Dose of Intrathecal Morphine a Useful Adjunct to Patient-Controlled Analgesia for Postoperative Pain Control Following Lumbar Spine Surgery? A Preliminary Report

2015 ◽  
Vol 20 (3) ◽  
pp. 129-132 ◽  
Author(s):  
David Yen ◽  
Kim Turner ◽  
David Mark
Keyword(s):  
Lumbar Spine ◽  
Postoperative Pain ◽  
Respiratory Depression ◽  
Spine Surgery ◽  
Pain Control ◽  
Low Dose ◽  
Intrathecal Morphine ◽  
Lumbar Spine Surgery ◽  
Patient Controlled Analgesia ◽  
Postoperative Pain Control

BACKGROUND: Several studies addressing intrathecal morphine (ITM) use following spine surgery have been published either involving the pediatric population, using mid- to high-dose ITM, or not in conjunction with morphine patient-controlled analgesia (PCA).OBJECTIVES: To determine whether low-dose ITM is a useful adjunct to PCA for postoperative pain control following elective lumbar spine surgery in adults.METHODS: Thirty-two patients were enrolled in a double-blinded randomized controlled trial, and received either ITM or intrathecal placebo. Postoperatively, all patients were given a PCA pump and observed for the first 24 h in a step-down unit. Measurements of: total PCA morphine consumed in the first 24 h; intensity of pain; pruritus; nausea at 4 h, 8 h and 24 h; time to first ambulation; length of hospital stay; and occurrences of respiratory depression were recorded.RESULTS: The total PCA use was significantly lower in the ITM group. There were lower average pain scores in the ITM group, which increased to that of the intrathecal placebo group over 24 h; however, this failed to attain statistical significance. There were no differences in nausea, pruritus, time to first ambulation or hospital length stay. There were no cases of respiratory depression in either group.CONCLUSIONS: ITM may be a useful adjunct to PCA, but did not decrease time to ambulation or length of stay.

Intrathecal Morphine during Lumbar Spine Operation for Postoperative Pain Control

Neurosurgery ◽  
1986 ◽  
Vol 18 (3) ◽  
pp. 341-344 ◽  
Author(s):  
J. Bob Blacklock ◽  
Gary L. Rea ◽  
Robert E. Maxwell
Keyword(s):  
Lumbar Spine ◽  
Treatment Group ◽  
Postoperative Pain ◽  
Urinary Retention ◽  
Pain Control ◽  
Intrathecal Morphine ◽  
Test Group ◽  
Bladder Function ◽  
Postoperative Pain Control

Abstract The analgesic requirements and bladder function of 5 patients who received 1 mg of intrathecal morphine during lumbar spine operation are compared to those of 10 control patients. No analgesics were used by the treatment group for the first 24 hours postoperatively. The test group subsequently required twice the amount of analgesics during the 2nd through 5th days after operation compared to controls. All 5 patients who received intrathecal morphine developed urinary retention for 24 to 36 hours. The brief duration of analgesia, the increased narcotic use after the effects of the morphine dissipated, and urinary retention after a single intraoperative dose of intrathecal morphine suggest caution in using this technique.

Small Doses of Intrathecal Morphine Combined with Systemic Diclofenac for Postoperative Pain Control After Cesarean Delivery

1998 ◽  
Vol 86 (3) ◽  
pp. 538-541 ◽  
Author(s):  
Monica M. S. C. Cardoso ◽  
Jose C. A. Carvalho ◽  
Antonio R. Amaro ◽  
Ademar A. Prado ◽  
Elizabeth L. Cappelli
Keyword(s):  
Postoperative Pain ◽  
Cesarean Delivery ◽  
Pain Control ◽  
Intrathecal Morphine ◽  
Postoperative Pain Control ◽  
Small Doses
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