Donor safety and remnant liver volume in living donor liver transplantation

2008 ◽  
Vol 14 (8) ◽  
pp. 1174-1179 ◽  
Author(s):  
C. Burcin Taner ◽  
Murat Dayangac ◽  
Baris Akin ◽  
Deniz Balci ◽  
Suleyman Uraz ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Liver Volume ◽  
Remnant Liver ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Remnant Liver Volume ◽  
Donor Safety

Evaluation of liver function before living donor liver transplantation and liver resection

2008 ◽  
Vol 149 (17) ◽  
pp. 779-786 ◽  
Author(s):  
Tamás Mándli ◽  
János Fazakas ◽  
Gábor Ther ◽  
Mónika Árkosy ◽  
Balázs Füle ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Resection ◽  
Liver Function ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Liver Volume ◽  
Hepatobiliary Scintigraphy ◽  
Remnant Liver ◽  
Donor Liver ◽  
Donor Liver Transplantation

Liver resection is the curative therapeutic option for hepatocellular carcinoma, biliary tumors, metastases of colorectal and other extrahepatic tumors, living donor liver transplantation and other benign liver diseases. Aim of study: To summarize the evaluation methods of liver function before living donor liver transplantation and liver resection. Method: We summarize the literature about the evaluation of liver function. Results: Perioperative mortality is determined mostly by the extent of preoperative evaluation focused on the liver. After resection the remnant liver parenchyma must cope with the challenge caused by increased metabolism, portal overflow, decreased vascular bed and biliary tract and oxidative stress following the operation. If the remnant liver is unable to grow up to this challenge, acute liver failure occurs. This maintains the necessity of determining the hepatic functional reserve and the hepatic remnant volume. Child–Pugh classification is widely spread to predict outcome. Dynamic functional tests such as indocyanin green retention test, galactosyl human serum albumin scintigraphy and aminopyrin breath tests can be used to evaluate hepatic reserve. To determine remnant liver volume modern imaging processes such as CT volumetry and hepatobiliary scintigraphy are available. Conclusion: After the detailed evaluation resection can be limited to an extent which is oncologically radical enough (1% remnant liver tissue/kg) and spares parenchyma which can ensure survival yet. With careful preoperative examination mortality can be reduced even to reach zero.

Donor safety in living donor liver transplantation: The Korean organ transplantation registry study

2017 ◽  
Vol 23 (8) ◽  
pp. 999-1006 ◽  
Author(s):  
Jae Geun Lee ◽  
Kwang-Woong Lee ◽  
Choon Hyuck David Kwon ◽  
Chong Woo Chu ◽  
Bong-Wan Kim ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Organ Transplantation ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Registry Study ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Donor Safety
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