scholarly journals Vaginal varices with massive hemorrhage in a patient with nonalcoholic steatohepatitis and portal hypertension: Successful treatment with liver transplantation

2008 ◽  
Vol 14 (10) ◽  
pp. 1538-1540 ◽  
Author(s):  
Patrick P. McHugh ◽  
Hoonbae Jeon ◽  
Roberto Gedaly ◽  
Thomas D. Johnston ◽  
Paul D. DePriest ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Portal Hypertension ◽  
Successful Treatment ◽  
Nonalcoholic Steatohepatitis ◽  
Massive Hemorrhage

Successful treatment of hepatitis C reinfection with interferon-alpha2b and ribavirin after liver transplantation. A long-term follow-up.

2005 ◽  
Vol 25 (4) ◽  
pp. 717-722 ◽  
Author(s):  
Suleyman Yedibela ◽  
Detlef Schuppan ◽  
Volker Muller ◽  
Vera Schellerer ◽  
Andrea Tannapfel ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hepatitis C ◽  
Successful Treatment ◽  
Long Term Follow Up ◽  
Hepatitis C Reinfection

Cirrhosis and Complications of Portal Hypertension

2018 ◽  
Author(s):  
Andres Cardenas ◽  
Isabel Graupera ◽  
Elsa Sola ◽  
Pere Ginès
Keyword(s):  
Liver Transplantation ◽  
Portal Hypertension ◽  
Variceal Bleeding ◽  
Bacterial Infections ◽  
Hepatorenal Syndrome ◽  
Wide Spectrum ◽  
Clinical Manifestations ◽  
Diagnostic Methods ◽  
Decompensated Cirrhosis ◽  
Ultrasound Images

Cirrhosis is the most advanced stage of all the different types of chronic liver diseases. It is defined as a diffuse disorganization of normal hepatic structure by extensive fibrosis associated with regenerative nodules. Hepatic fibrosis is potentially reversible if the causative agent is removed. However, advanced cirrhosis leads to major alterations in the hepatic vascular bed and is usually irreversible. Cirrhosis is a progressive and severe clinical condition associated with considerable morbidity and high mortality. It leads to a wide spectrum of characteristic clinical manifestations, mainly attributable to hepatic insufficiency and portal hypertension. Major complications of portal hypertension include ascites, gastrointestinal (GI) variceal bleeding, hepatic encephalopathy (HE), renal failure, and bacterial infections. In recent years, major advances in the understanding of the natural history and pathophysiology of cirrhosis and the treatment of its complications have led to improved management, quality of life, and life expectancy of patients with this disease. Cirrhosis is also a risk factor for developing hepatocellular carcinoma (HCC). Decompensated cirrhosis carries a poor short-term prognosis; thus, orthotopic liver transplantation (OLT) should always be considered in suitable candidates. This chapter describes the epidemiology, etiology and genetic factors, pathogenesis, diagnosis, general management, and treatment of cirrhosis. Complications of cirrhosis are discussed, including ascites, spontaneous bacterial peritonitis, dilutional hyponatremia, hepatorenal syndrome, variceal bleeding, hepatopulmonary syndrome and postpulmonary hypertension, HE, and HCC. Indications and contraindications for liver transplantation are described. Figures show liver biopsy results and ultrasound images in cirrhosis from hepatitis C, a patient with tense ascites, transjugular intrahepatic portosystemic shunting (TIPS), large esophageal varices with red spots, and HCC. Tables outline the main causes of cirrhosis and the diagnostic methods for identifying them, the Child-Pugh score, diagnostic criteria for hepatorenal syndrome, grades of HE, and indications for liver transplantation.This chapter contains 6 highly rendered figures, 8 tables, 73 references.

scholarly journals Redefining Cirrhosis – a brief review

2013 ◽  
Vol 3 (6) ◽  
pp. 491-496 ◽  
Author(s):  
SV Pradhan
Keyword(s):  
Portal Hypertension ◽  
Liver Damage ◽  
Successful Treatment ◽  
Classification System ◽  
Vascular Remodeling ◽  
Underlying Disease ◽  
Nodule Formation ◽  
Variable Amount ◽  
Histological Features

The liver damage is associated with variable amount of fibrosis. The presence of fibrosis with nodule formation is pathognomic of cirrhosis. It is accompanied by vascular remodeling and regeneration with important functional and hemodynamic consequences that include development of portal hypertension and eventually decompensation and death. However fibrosis can regress following successful treatment of the underlying disease. The classification system followed till date does not analyze this aspect. In this brief review the histological features of fibrosis and the newer models for reclassifying cirrhosis is discussed. DOI: http://dx.doi.org/10.3126/jpn.v3i6.9000 Journal of Pathology of Nepal (2013) Vol. 3, 491-496

High affinity anti-BSEP antibodies after liver transplantation for PFIC-2 - Successful treatment with immunoadsorption and B-cell depletion

2016 ◽  
Vol 20 (7) ◽  
pp. 987-993 ◽  
Author(s):  
Ralf Kubitz ◽  
Carola Dröge ◽  
Stefanie Kluge ◽  
Jan Stindt ◽  
Claudia Stross ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
B Cell ◽  
Successful Treatment ◽  
Cell Depletion ◽  
B Cell Depletion ◽  
High Affinity

Failure of hepatopulmonary syndrome to resolve after liver transplantation and successful treatment with embolotherapy

Hepatology ◽  
1995 ◽  
Vol 21 (1) ◽  
pp. 96-100 ◽  
Author(s):  
John J. Poterucha ◽  
Michael J. Krowka ◽  
E. Rolland Dickson ◽  
Denis A. Cortese ◽  
Anthony W. Stanson ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Successful Treatment ◽  
Hepatopulmonary Syndrome

Successful Treatment of Fulminant Echovirus 11 Infection in a Neonate by Orthotopic Liver Transplantation

1993 ◽  
Vol 17 (2) ◽  
pp. 211-214 ◽  
Author(s):  
Emil Chuang ◽  
Eric S. Maller ◽  
Mark A. Hoffman ◽  
Richard L. Hodinka ◽  
Steven M. Altschuler
Keyword(s):  
Liver Transplantation ◽  
Orthotopic Liver Transplantation ◽  
Successful Treatment
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