scholarly journals Living donor liver transplant for fibrolamellar hepatocellular carcinoma using a deceased donor graft to reconstruct inferior vena cava

2004 ◽  
Vol 10 (4) ◽  
pp. 555-556 ◽  
Author(s):  
Kellee Slater ◽  
Thomas E. Bak ◽  
Igal Kam ◽  
Michael E. Wachs
Keyword(s):  
Hepatocellular Carcinoma ◽  
Living Donor ◽  
Inferior Vena ◽  
Vena Cava ◽  
Deceased Donor ◽  
Donor Liver ◽  
Fibrolamellar Hepatocellular Carcinoma ◽  
Living Donor Liver Transplant ◽  
Donor Graft ◽  
Donor Liver Transplant

scholarly journals Living donor liver transplantation for hepatocellular carcinoma beyond the Milan criteria: outcome of expanded criteria in tumor size

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hsin-Rou Liang ◽  
Chia-En Hsieh ◽  
Kuo-Hua Lin ◽  
Chih-Jan Ko ◽  
Yu-Ju Hung ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Living Donor ◽  
Milan Criteria ◽  
Tumor Diameter ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Living Donor Liver Transplant ◽  
Expanded Criteria ◽  
Donor Liver Transplant

Abstract Background The Milan criteria are the universal standard of liver transplantation for hepatocellular carcinoma (HCC). Numerous expanded criteria have shown outcomes as good as the Milan criteria. In Taiwan, living donor liver transplant (LDLT) accounts for the majority of transplantations due to organ shortages. Methods We retrospectively enrolled 155 patients who underwent LDLT for HCC from July 2005 to June 2017 and were followed up for at least 2 years. Patients beyond the Milan criteria (n = 78) were grouped as recurrent or nonrecurrent, and we established new expanded criteria based on these data. Results Patients beyond the Milan criteria with recurrence (n = 31) had a significantly larger maximal tumor diameter (4.13 ± 1.96 cm versus 6.10 ± 3.41 cm, p = 0.006) and total tumor diameter (7.19 ± 4.13 cm versus 10.21 ± 5.01 cm, p = 0.005). Therefore, we established expanded criteria involving maximal tumor diameter ≤ 6 cm and total tumor diameter < 10 cm. The 5-year survival rate of patients who met these criteria (n = 134) was 77.3%, and the 5-year recurrence rate was 20.5%; both showed no significant differences from those of the Milan criteria. Under the expanded criteria, the pool of eligible recipients was 35% larger than that of the Milan criteria. Conclusion Currently, patients with HCC who undergo LDLT can achieve good outcomes even when they are beyond the Milan criteria. Under the new expanded criteria, patients can achieve outcomes as good as those with the Milan criteria and more patients can benefit.

scholarly journals Living Donor Liver Transplant as Rescue Surgery for a Patient with Hepatocellular Carcinoma Who Underwent Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS)

2018 ◽  
Vol 19 ◽  
pp. 1338-1341
Author(s):  
Eduardo de Souza Martins Fernandes ◽  
Felipe Pedreira Tavares de Mello ◽  
Ronaldo Oliveira Andrade ◽  
Camila Liberato Girao ◽  
Leandro Savattone Pimentel ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Portal Vein ◽  
Liver Transplant ◽  
Living Donor ◽  
Portal Vein Ligation ◽  
Donor Liver ◽  
Living Donor Liver Transplant ◽  
Donor Liver Transplant ◽  
Staged Hepatectomy

Candidate Criteria for Living Versus Deceased Donor Liver Grafts

2021 ◽  
pp. 327-349
Author(s):  
Lainie Friedman ◽  
J. Richard Thistlethwaite, Jr
Keyword(s):  
Liver Transplant ◽  
Living Donor ◽  
Suicide Attempts ◽  
Deceased Donor ◽  
Young Female ◽  
Donor Liver ◽  
First Case ◽  
Living Donor Liver Transplant ◽  
History Of ◽  
Donor Liver Transplant

This chapter explores whether living donor liver transplant (LDLT) is morally permissible when the candidate is ineligible for a deceased donor liver transplant (DDLT). Two cases are evaluated: a woman with metastatic colorectal cancer (CRC) and a young female liver transplant recipient with a history of multiple suicide attempts who is in acute liver failure due to another intentional drug overdose. Although both women could benefit (gain life years) from liver transplant, neither is deemed eligible for DDLT by their transplant teams because of a short post-transplant life expectancy in the first case and expected poor organ stewardship in the second case. This chapter argues that LDLT is morally permissible in candidates ineligible for DDLT if the living donor provides a voluntary informed consent, knows he or she can withdraw at any time, and understands that the recipient candidate will not be listed for a DDLT should the LDLT fail.

scholarly journals Perioperative Bacterial Infections in Deceased Donor and Living Donor Liver Transplant Recipients

2012 ◽  
Vol 2 (1) ◽  
pp. 35-41 ◽  
Author(s):  
Joy Varghese ◽  
Narasimhan Gomathy ◽  
Perumalla Rajashekhar ◽  
Kota Venugopal ◽  
Arikichenin Olithselvan ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Bacterial Infections ◽  
Living Donor ◽  
Deceased Donor ◽  
Transplant Recipients ◽  
Donor Liver ◽  
Living Donor Liver Transplant ◽  
Donor Liver Transplant ◽  
Liver Transplant Recipients
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