Subcutaneous adipose tissue response to a non-invasive hyperthermic treatment using a 1,060 nm laser

2017 ◽  
Vol 49 (5) ◽  
pp. 480-489 ◽  
Author(s):  
John W. Decorato ◽  
Bo Chen ◽  
Rafael Sierra
Keyword(s):  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Tissue Response ◽  
Non Invasive ◽  
Hyperthermic Treatment ◽  
Subcutaneous Adipose

scholarly journals New System Delivering Microwaves Energy for Inducing Subcutaneous Fat Reduction: In - Vivo Histological and Ultrastructural Evidence

2019 ◽  
Vol 7 (18) ◽  
pp. 2991-2997 ◽  
Author(s):  
Nicola Zerbinati ◽  
Edoardo D’Este ◽  
Antonia Icaro Cornaglia ◽  
Federica Riva ◽  
Aurora Farina ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Subcutaneous Fat ◽  
The Body ◽  
Invasive Treatment ◽  
New Device ◽  
Non Invasive ◽  
Ultrastructural Evidence ◽  
Subcutaneous Adipose

BACKGROUND: Recently, it has been developed a new technology for the reduction of subcutaneous adipose tissue through a non-invasive treatment by microwaves. The main objective of the present study is to demonstrate the feasibility of utilising a non-invasive, localised microwaves (MW) device to induce thermal modifications into subcutaneous adipose tissue only by a controlled electromagnetic field that heats up fat preferentially. This device is provided with a special handpiece appropriately cooled, directly contacting the cutaneous surface of the body, which provides a calibrated energy transfer by microwaves. AIM: In this paper, microscopic and ultrastructural modifications of subcutaneous adipose tissue induced by microwaves irradiation are evaluated. METHODS: Our experimental plan was designed for collecting biopsy samples, for each skin region treated with a single irradiation session, 1) before treatment (control), 2) immediately after treatment, 3) after 6 hrs, 4) after 1 month, 5) after 2 months. Bioptic samples from each step were processed for light microscopy and transmission electron microscopy. At the same time, each region where biopsies were collected was subjected to ultrasound examination. Recorded images permitted to evaluate the thickness of different layers as epidermis, dermis, hypodermis, connective fasciae, until to muscle layer, and related modifications induced by treatment. RESULTS: In every biopsy collected at different time-steps, epidermis and superficial dermis appeared not modified compared to control. Differently, already in the short-term biopsies, in the deep dermis and superficial hypodermis, fibrillar connective tissue appeared modified, showing reduction and fragmentation of interlobular collagen septa. The most important adipose tissue modifications were detectable following 1 month from treatment, with a significant reduction of subcutaneous fat, participating both the lysis of many adipocytes and the related phagocytic action of monocytes/macrophages on residuals of compromised structures of adipocytes. In the samples collected two months following treatment, the remnants of adipose tissue appeared normal, and macrophages were completely absent. CONCLUSIONS: Ultrasound, microscopic and ultrastructural evidence are supporting significant effectiveness of the new device treatment in the reduction of subcutaneous fat. In this paper, the possible mechanisms involved in the activation of the monocytes/macrophages system responsible for the removal of adipocytes residuals have also been discussed.

scholarly journals Development of a non-invasive measurement system to the thickness of the subcutaneous adipose tissue layer

2008 ◽  
Vol 17 (6) ◽  
pp. 537-541 ◽  
Author(s):  
Yeon Shik Choi ◽  
Hyuck Ki Hong ◽  
Beom Joon Kim ◽  
Myeung Nam Kim ◽  
Hyo Derk Park
Keyword(s):  
Adipose Tissue ◽  
Measurement System ◽  
Subcutaneous Adipose Tissue ◽  
Tissue Layer ◽  
Non Invasive ◽  
Subcutaneous Adipose ◽  
Invasive Measurement

Insulin resistance, systemic and regional inflammation in subcutaneous adipose tissue during weight loss in a population with obesity

2019 ◽  
Author(s):  
Frederique Van de Velde ◽  
Margriet Ouwens ◽  
Arsene-Helene Batens ◽  
Samyah Shadid ◽  
Bruno Lapauw ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Weight Loss ◽  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Subcutaneous Adipose

701-P: Effects of Exercise on Extracellular Matrix Modifiers in Subcutaneous Adipose Tissue of Obese Adults

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 701-P
Author(s):  
PALLAVI VARSHNEY ◽  
BENJAMIN J. RYAN ◽  
CHIWOON AHN ◽  
MICHAEL W. SCHLEH ◽  
JEFFREY F. HOROWITZ
Keyword(s):  
Extracellular Matrix ◽  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Obese Adults ◽  
Subcutaneous Adipose
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