Transcutaneous drug delivery by liposomes using fractional laser technology

2016 ◽  
Vol 49 (5) ◽  
pp. 525-532 ◽  
Author(s):  
Takahiro Fujimoto ◽  
Jian Wang ◽  
Kazuki Baba ◽  
Yuka Oki ◽  
Yuki Hiruta ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Fractional Laser ◽  
Laser Technology ◽  
Transcutaneous Drug Delivery

scholarly journals Facilitation of transcutaneous drug delivery and vaccine immunization by a safe laser technology

2012 ◽  
Vol 159 (1) ◽  
pp. 43-51 ◽  
Author(s):  
Xinyuan Chen ◽  
Dilip Shah ◽  
Garuna Kositratna ◽  
Dieter Manstein ◽  
Richard R. Anderson ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Laser Technology ◽  
Transcutaneous Drug Delivery

scholarly journals Transcutaneous Drug Delivery Systems Based on Collagen/Polyurethane Composites Reinforced with Cellulose

Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1845
Author(s):  
Narcis Anghel ◽  
Valentina Maria Dinu ◽  
Liliana Verestiuc ◽  
Irene Alexandra Spiridon
Keyword(s):  
Drug Delivery ◽  
Compressive Strength ◽  
Elastic Modulus ◽  
Metal Complex ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Fickian Diffusion ◽  
Mechanical Resistance ◽  
Natural Polymers ◽  
Transcutaneous Drug Delivery

Designing composites based on natural polymers has attracted attention for more than a decade due to the possibility to manufacture medical devices which are biocompatible with the human body. Herein, we present some biomaterials made up of collagen, polyurethane, and cellulose doped with lignin and lignin-metal complex, which served as transcutaneous drug delivery systems. Compared with base material, the compressive strength and the elastic modulus of biocomposites comprising lignin or lignin-metal complex were significantly enhanced; thus, the compressive strength increased from 61.37 to 186.5 kPa, while the elastic modulus increased from 0.828 to 1.928 MPa. The release of ketokonazole from the polymer matrix follows a Korsmeyer–Peppas type kinetics with a Fickian diffusion. All materials tested were shown to be active against pathogenic microorganisms. The mucoadhesiveness, bioadhesiveness, mechanical resistance, release kinetic, and antimicrobial activity make these biocomposites to be candidates as potential systems for controlled drug release.

The rise of transcutaneous drug delivery for the management of alopecia: a review of existing literature and an eye towards the future

2018 ◽  
Vol 21 (5) ◽  
pp. 247-254 ◽  
Author(s):  
Angela Wipf ◽  
Nicholas Boysen ◽  
Maria K. Hordinsky ◽  
Emily E. Dando ◽  
Neil Sadick ◽  
...  
Keyword(s):  
Drug Delivery ◽  
The Future ◽  
Transcutaneous Drug Delivery

scholarly journals Fractional laser and laser assisted corticosteroid delivery for hypertrophic scars in thermal burns

2019 ◽  
Author(s):  
Ni Putu Susari Widianingsih ◽  
Cita Rosita S. Prakoeswa
Keyword(s):  
Clinical Trial ◽  
Case Report ◽  
Therapeutic Option ◽  
Burn Patients ◽  
Hypertrophic Scars ◽  
Fractional Laser ◽  
Laser Technology ◽  
Thermal Burns ◽  
Post Operative Period ◽  
Other Substances

The unprecedented survival of individuals who sustain acute burns and other trauma has increased the necessity for effective modalities in the treatment and rehabilitation of patients. Hypertrophic scars and contractures are common following thermal burns injury. Cutaneous scars can be complex and thus the approach to therapy is often multimodal with only moderate success. Intralesional corticosteroids have long been a main treatment of hypertrophic and restrictive scars. Recent advance in laser technology and applications now provide additional options for improvements in function, symptoms, and cosmesis. The ablative zones created by fractional ablative lasers may also be used in the immediate post-operative period to enhance delivery of drugs and other substances. This case report shows the successful use of fractional laser assisted corticosteroid to treat burn scars. It is need more extensive clinical trial to prove this method can be a therapeutic option for the extensive cutaneous scarring in burn patients.

Laser-assisted topical drug delivery by using a low-fluence fractional laser: Imiquimod and macromolecules

2011 ◽  
Vol 153 (3) ◽  
pp. 240-248 ◽  
Author(s):  
Woan-Ruoh Lee ◽  
Shing-Chuan Shen ◽  
Saleh A. Al-Suwayeh ◽  
Hung-Hsu Yang ◽  
Cheng-Yin Yuan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Topical Drug Delivery ◽  
Fractional Laser

scholarly journals Feasibility of ablative fractional laser-assisted drug delivery with optical coherence tomography

2014 ◽  
Vol 5 (11) ◽  
pp. 3949 ◽  
Author(s):  
Chih-Hsun Yang ◽  
Meng-Tsan Tsai ◽  
Su-Chin Shen ◽  
Chau Yee Ng ◽  
Shih-Ming Jung
Keyword(s):  
Drug Delivery ◽  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Fractional Laser ◽  
Ablative Fractional Laser
Sign in / Sign up

Export Citation Format

Share Document