Clinical, biophysical, immunohistochemical, and in vivo reflectance confocal microscopy evaluation of the response of subjects with sensitive skin to home-use fractional non-ablative photothermolysis device

2016 ◽  
Vol 48 (5) ◽  
pp. 474-482 ◽  
Author(s):  
Renée J.H. Richters ◽  
Lisa Hoogedoorn ◽  
Natallia E. Uzunbajakava ◽  
Lisanne D. Janssen ◽  
A.M. Tom Nuijs ◽  
...  
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hye-Jin Ahn ◽  
Hae Jin Kim ◽  
Hyein Ham ◽  
Ji Hwoon Baek ◽  
Young Lee ◽  
...  

AbstractFindings obtained on objective assessments to evaluate sensitive skin do not correlate well with the symptomatology. We utilized reflectance confocal microscopy (RCM) to compare transepidermal application of zinc in sensitive and non-sensitive skin. Thirty-six subjects participated in this study. They were divided into groups based on lactic acid sting test (LAST):‘stinger’ and ‘non-stinger’; transepidermal water loss (TEWL) measurements; and sensitivity self-assessments: ‘sensitive’ and ‘non-sensitive’. RCM images were taken to visualize transepidermal application of topically-applied zinc. The intensity of zinc reflectance at different depths was measured by ImageJ software. Based on LAST scores, the ‘stinger’ group showed significantly higher reflectance of zinc at 8 µm (stratum corneum) [face (P < 0.001), forearm (P = 0.004)], and at 80–104 µm (dermo-epidermal junction layer) on the face. High-TEWL group showed increased zinc reflectance at 8–24 µm (tight junction layer, P < 0.001). There were no significant differences amongst subjects self-reporting ‘sensitive’ and ‘non-sensitive’ skin. RCM demonstrates that in sensitive skin, there is deeper and higher reflectance of zinc at multiple depths. Structural differences are also visualized. We suggest that RCM is a useful tool for evaluating skin barrier integrity.


Author(s):  
Arianna Rizzo ◽  
Diletta Fiorani ◽  
Laura Lazzeri ◽  
Paolo Taddeucci ◽  
Pietro Rubegni ◽  
...  

2021 ◽  
Vol 14 (1) ◽  
pp. e240507
Author(s):  
Mihai Lupu ◽  
Vlad Mihai Voiculescu ◽  
Cristina Vajaitu ◽  
Olguta Anca Orzan

Author(s):  
Cristian Navarrete‐Dechent ◽  
Miguel Cordova ◽  
Saud Aleissa ◽  
Alexander Shoushtari ◽  
Travis J. Hollmann ◽  
...  

Author(s):  
Samavia Khan ◽  
Nadiya Chuchvara ◽  
Jennifer Cucalon ◽  
Attiya Haroon ◽  
Babar Rao

2016 ◽  
Vol 75 (5) ◽  
pp. e185-e187 ◽  
Author(s):  
Marina Venturini ◽  
Arianna Zanca ◽  
Ausilia Maria Manganoni ◽  
Laura Pavoni ◽  
Giulio Gualdi ◽  
...  

2016 ◽  
Vol 23 (2) ◽  
pp. 227-234 ◽  
Author(s):  
Y.-F. Ma ◽  
C. Yuan ◽  
W.-C. Jiang ◽  
X.-L. Wang ◽  
P. Humbert

2018 ◽  
Vol 58 (2) ◽  
pp. e30-e32 ◽  
Author(s):  
Paola Pasquali ◽  
Gonzalo Segurado-Miravalles ◽  
Azael Freites-Martínez ◽  
Salvador González-Rodriguez

2018 ◽  
Vol 4 (9) ◽  
pp. 918-920
Author(s):  
Melody Maarouf ◽  
Clara Curiel-Lewandrowski ◽  
Sarah Daley ◽  
Phillip Kuo ◽  
Emad Elquza ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document