The hyper‐fluorescent transitional bands in ultra‐late phase of indocyanine green angiography in chronic central serous chorioretinopathy

2015 ◽  
Vol 48 (3) ◽  
pp. 260-263 ◽  
Author(s):  
Rui Hua ◽  
Kai Yao ◽  
Fan Xia ◽  
Jun Li ◽  
Lei Guo ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Central Serous Chorioretinopathy ◽  
Indocyanine Green Angiography ◽  
Late Phase ◽  
Chronic Central Serous Chorioretinopathy

Identifying central serous chorioretinopathy biomarkers in coexisting diabetic retinopathy: a multimodal imaging study

2019 ◽  
Vol 104 (7) ◽  
pp. 904-909
Author(s):  
Deven Sushil Dhurandhar ◽  
Sumit Randhir Singh ◽  
Niroj Kumar Sahoo ◽  
Abhilash Goud ◽  
Marco Lupidi ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Indocyanine Green ◽  
Central Serous Chorioretinopathy ◽  
Indocyanine Green Angiography ◽  
Diabetic Macular Oedema ◽  
Imaging Study ◽  
Prior History ◽  
Chronic Central Serous Chorioretinopathy ◽  
Cross Sectional ◽  
Imaging Characteristics

BackgroundTo describe clinical and imaging characteristics of patients presenting with diabetic retinopathy (DR) with coexisting acute or chronic central serous chorioretinopathy (CSCR).MethodsThis was a cross-sectional study which included 54 eyes of 27 patients with coexisting DR and CSCR. Demographic details, prior history of laser, best-corrected visual acuity (BCVA), central macular thickness (CMT), height of neurosensory detachment (NSD), subfoveal choroidal thickness (SFCT), subfoveal large choroidal vessel layer thickness (SF-LCVT), fluorescein angiography and indocyanine green angiography features were recorded. Subanalysis was done for patients with unilateral CSCR. Data was evaluated using Student t-test for quantitative data and χ2 test for qualitative data. CSCR between different grades of DR was analysed using analysis of variance.ResultsPrevalence of coexistent CSCR in eyes with DR was 0.4%. Mean age was 53.96±8.79 years, with 25 males. Mean CMT was 349.2±258 μm. Mean SFCT and SF- LCVT of 38 eyes were 376.40±86 μm and 178.80±62.8 μm, respectively. Fifteen eyes had centre involving diabetic macular oedema. Subanalysis of patients with unilateral CSCR showed that the loss of inner segment-outer segment (IS-OS) integrity (p=0.001), photoreceptor footplates at the NSD roof (p=0.001) on optical coherence tomography and dilated choroidal vessels (p=0.05) on indocyanine green angiography were found more often in the CSCR eyes compared with their fellow eyes. Features of CSCR among the different grades of DR were not significantly different between the groups.ConclusionOur study describes features of a unique subset of patients presenting with coexistent DR and CSCR. Such coexistent nature needs special attention by the clinicians as this may change the treatment approach and alter outcomes.

scholarly journals OCT Angiography Compared to Fluorescein and Indocyanine Green Angiography in Chronic Central Serous Chorioretinopathy

2015 ◽  
Vol 56 (9) ◽  
pp. 5229 ◽  
Author(s):  
Michel M. Teussink ◽  
Myrte B. Breukink ◽  
Mark J. J. P. van Grinsven ◽  
Carel B. Hoyng ◽  
B. Jeroen Klevering ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Central Serous Chorioretinopathy ◽  
Indocyanine Green Angiography ◽  
Oct Angiography ◽  
Chronic Central Serous Chorioretinopathy

scholarly journals Indocyanine green angiography in chronic central serous chorioretinopathy

2012 ◽  
Vol 18 (2) ◽  
pp. CR51-CR57 ◽  
Author(s):  
Urszula Gajdzik-Gajdecka ◽  
Mariola Dorecka ◽  
Ewa Nita ◽  
Anna Michalska ◽  
Joanna Miniewicz-Kurowska ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Central Serous Chorioretinopathy ◽  
Indocyanine Green Angiography ◽  
Chronic Central Serous Chorioretinopathy

Investigation of the Etiology of Central Serous Chorioretinopathy Using En-Face Optical Coherence Tomography and Indocyanine Green Angiography

2016 ◽  
Vol 236 (2) ◽  
pp. 100-107 ◽  
Author(s):  
Ari Shinojima ◽  
Kyoko Fujita ◽  
Ryusaburo Mori ◽  
Akiyuki Kawamura ◽  
Mitsuko Yuzawa ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Indocyanine Green ◽  
Central Serous Chorioretinopathy ◽  
Indocyanine Green Angiography ◽  
Late Phase ◽  
Optical Coherence ◽  
Swept Source ◽  
Face Images ◽  
En Face ◽  
Swept Source Oct

Purpose: To identify locations of hypofluorescent lesions on late-phase indocyanine green angiography (ICGA) in patients with central serous chorioretinopathy (CSC) using en-face optical coherence tomography (OCT). Procedures: We retrospectively studied 25 consecutive untreated CSC patients, using swept-source OCT and ICGA. En-face swept-source OCT images were automatically segmented and flattened with Bruch's membrane (BrM). We compared the sizes of hyperreflective areas in the 25 CSC and 25 contralateral eyes on en-face images and hypofluorescent areas on ICGA after 30 min. Results: All 25 CSC eyes and 13 contralateral eyes showed abnormal hypofluorescent areas on late-phase ICGA and hyperreflective areas on en-face OCT from BrM to the choriocapillaris, and these findings correlated with the abnormal areas (r = 0.9988; p < 0.001). Conclusions: In CSC patients, we detected abnormal hypofluorescence on ICGA in the late phase, which corresponded to abnormal hyperreflective areas from BrM to the choriocapillaris level in en-face images.

scholarly journals Assessment of Hypofluorescent Foci on Late-Phase Indocyanine Green Angiography in Central Serous Chorioretinopathy

2021 ◽  
Vol 10 (10) ◽  
pp. 2178
Author(s):  
Ari Shinojima ◽  
Yoko Ozawa ◽  
Atsuro Uchida ◽  
Norihiro Nagai ◽  
Hajime Shinoda ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Central Serous Chorioretinopathy ◽  
Indocyanine Green Angiography ◽  
Near Infrared ◽  
Pigment Epithelium ◽  
Fundus Autofluorescence ◽  
Retinal Pigment ◽  
Late Phase ◽  
Standard Deviation Range ◽  
Simple Regression Analysis

To assess the hypofluorescent foci (HFF) on late-phase indocyanine green angiography (ICGA) in central serous chorioretinopathy (CSC) using short-wavelength fundus autofluorescence (SW-FAF), near-infrared autofluorescence (NIR-AF), and fluorescein angiography (FA). The HFF area on late-phase ICGA for at least 20 min was compared with the area of abnormal foci on SW-FAF, NIR-AF, and FA. In 14 consecutive patients (12 men, including 1 with bilateral CSC; and 2 women with unilateral CSC), four kinds of images of 27 eyes were acquired. The mean age ± standard deviation (range) was 46 ± 9.2 years (31–69 years). The HFF on late-phase ICGA were found in 23 eyes (in all 15 CSC eyes and the contralateral 8 eyes). From the results of simple regression analysis, we obtained the following three formulas. The HFF area on ICGA = 1.058 × [abnormal SW-FAF area] + 0.135, the HFF area on ICGA = 1.001 × [abnormal NIR-AF area] + 0.015, and the HFF area on ICGA = 1.089 × [abnormal FA area] + 0.135. Compared to SW-FAF and FA, NIR-AF was found to be the easiest method to detect the HFF on late-phase ICGA, which may indicate melanin abnormalities, especially a decrease, in the retinal pigment epithelium.

scholarly journals Accordance of Indocyanine Green Angiography and Optical Coherence Tomography Angiography in Visualization of Neovascularization Associated with Chronic Central Serous Chorioretinopathy

2018 ◽  
Vol 15 (2S) ◽  
pp. 254-260
Author(s):  
E. K. Pedanova ◽  
O. B. Klepinina ◽  
D. A. Buryakov
Keyword(s):  
Optical Coherence Tomography ◽  
Indocyanine Green ◽  
Central Serous Chorioretinopathy ◽  
Indocyanine Green Angiography ◽  
Optical Coherence Tomography Angiography ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Diagnostic Methods ◽  
Optical Coherence ◽  
Chronic Central Serous Chorioretinopathy

Purpose: to compare informativity and accordance of indocyanine green angiography (ICGA) and optical coherence tomography angiography (OCT-A) data in visualization of neovascularization associated with chronic central serous chorioretinopathy. Patients andMethods. Twenty one eye of 21 patients (aged 51.0 ± 8.4 years old) with chronic central serous chorioretinopathy (CSR) and assumed choroidal neovascularisation (CNV) with «double layer» sign on optical coherence tomography scans were enrolled in this study. ICGA on Spectralis HRA+OCT, (Heidelberg Engeneering, Germany) and OCT-A on RTVue XR Avanti (Optovue, USA) were performed to evaluate CNV. The assessment of obtained pictures was examined by two experts.Results. Both diagnostic methods have shown similar results. CNV has been revealed in 11 of 21 eyes by ICGA imaging while OCT-A confirmed neovascularization in 13 eyes — with no statistical difference between methods (p = 0.74, χ2). CNV has not been diagnosed in 10 cases by ICGA and in 8 cases by OCT-A (p = 0.69). However, the consistency of the two methods in CNV evaluation while pairwise comparison of angiography data has been confirmed only in 8 eyes. The absence of CNV has been confirmed in 6 eyes — mostly in patients with CSR recurrence. One third of patients (7 of 21 eyes) have not shown consistence of two methods. The OCT-A visualization of CNV could be poor because of subretinal deposits and pigment-related signal blocking. In cases of diffuse retinal pigment epithelium atrophy the neovascular network cannot been seen on ICGA images while well visualized on OCT-A.Conclusion. The informativity of ICGA and OCT-A in visualization of neovascularization associated with chronic central serous chorioretinopathy is similar. For the best data interpretation the condition of neurosensory retina and pigment retinal epitheluium should be taken into account. OCT-A is more preferable in cases of diffuse epitheliopathy, while the neovascularization activity and leakage points is better seen on ICGA. 

INDOCYANINE GREEN ANGIOGRAPHY-GUIDED PHOTODYNAMIC THERAPY FOR TREATMENT OF CHRONIC CENTRAL SEROUS CHORIORETINOPATHY

Retina ◽  
2012 ◽  
Vol 32 ◽  
pp. 288-298 ◽  
Author(s):  
Lawrence A. Yannuzzi ◽  
Jason S. Slakter ◽  
Nicole E. Gross ◽  
Richard F. Spaide ◽  
Danielle L.L. Costa ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Indocyanine Green ◽  
Central Serous Chorioretinopathy ◽  
Indocyanine Green Angiography ◽  
Chronic Central Serous Chorioretinopathy
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