scholarly journals The promise of immunotherapy in the treatment of young adults with oral tongue cancer

2020 ◽  
Vol 5 (2) ◽  
pp. 235-242 ◽  
Author(s):  
Hassan Nasser ◽  
Maie A. St. John
Keyword(s):  
Young Adults ◽  
Tongue Cancer ◽  
Oral Tongue ◽  
Oral Tongue Cancer

Diverging incidence trends of oral tongue cancer compared with other head and neck cancers in young adults in France

2021 ◽  
Author(s):  
Sophie Deneuve ◽  
Olivia Pérol ◽  
Emmanuelle Dantony ◽  
Anne‐Valérie Guizard ◽  
Nadine Bossard ◽  
...  
Keyword(s):  
Young Adults ◽  
Head And Neck ◽  
Tongue Cancer ◽  
Head And Neck Cancers ◽  
Oral Tongue ◽  
Incidence Trends ◽  
Oral Tongue Cancer

Clinical features and outcomes in young adults with oral tongue cancer

2019 ◽  
Vol 40 (1) ◽  
pp. 93-96 ◽  
Author(s):  
Courtney Miller ◽  
Aryan Shay ◽  
Bobby Tajudeen ◽  
Neilayan Sen ◽  
Mary Fidler ◽  
...  
Keyword(s):  
Young Adults ◽  
Clinical Features ◽  
Tongue Cancer ◽  
Oral Tongue ◽  
Oral Tongue Cancer

scholarly journals Improving Risk Stratification of Early Oral Tongue Cancer with TNM-Immune (TNM-I) Staging System

Cancers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 3235
Author(s):  
Alhadi Almangush ◽  
Ibrahim O. Bello ◽  
Ilkka Heikkinen ◽  
Jaana Hagström ◽  
Caj Haglund ◽  
...  
Keyword(s):  
Overall Survival ◽  
Tongue Cancer ◽  
Early Stage ◽  
Disease Free Survival ◽  
Tumor Infiltrating Lymphocytes ◽  
Staging System ◽  
Oral Tongue ◽  
Oral Tongue Cancer ◽  
Important Player ◽  
Infiltrating Lymphocytes

Although patients with early-stage oral tongue squamous cell carcinoma (OTSCC) show better survival than those with advanced disease, there is still a number of early-stage cases who will suffer from recurrence, cancer-related mortality and worse overall survival. Incorporation of an immune descriptive factor in the staging system can aid in improving risk assessment of early OTSCC. A total of 290 cases of early-stage OTSCC re-classified according to the American Joint Committee on Cancer (AJCC 8) staging were included in this study. Scores of tumor-infiltrating lymphocytes (TILs) were divided as low or high and incorporated in TNM AJCC 8 to form our proposed TNM-Immune system. Using AJCC 8, there were no significant differences in survival between T1 and T2 tumors (p > 0.05). Our proposed TNM-Immune staging system allowed for significant discrimination in risk between tumors of T1N0M0-Immune vs. T2N0M0-Immune. The latter associated with a worse overall survival with hazard ratio (HR) of 2.87 (95% CI 1.92–4.28; p < 0.001); HR of 2.41 (95% CI 1.26–4.60; p = 0.008) for disease-specific survival; and HR of 1.97 (95% CI 1.13–3.43; p = 0.017) for disease-free survival. The TNM-Immune staging system showed a powerful ability to identify cases with worse survival. The immune response is an important player which can be assessed by evaluating TILs, and it can be implemented in the staging criteria of early OTSCC. TNM-Immune staging forms a step towards a more personalized classification of early OTSCC.

scholarly journals A systematic review and meta‐analysis of the prognostic role of age in oral tongue cancer

2021 ◽  
Author(s):  
Marta Tagliabue ◽  
Pietro Belloni ◽  
Rita De Berardinis ◽  
Sara Gandini ◽  
Francesco Chu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Tongue Cancer ◽  
Meta Analysis ◽  
Oral Tongue ◽  
Prognostic Role ◽  
Oral Tongue Cancer

Rising incidence of oral tongue cancer among white men and women in the United States, 1973–2012

Oral Oncology ◽  
2017 ◽  
Vol 67 ◽  
pp. 146-152 ◽  
Author(s):  
Joseph E. Tota ◽  
William F. Anderson ◽  
Charles Coffey ◽  
Joseph Califano ◽  
Wendy Cozen ◽  
...  
Keyword(s):  
United States ◽  
Tongue Cancer ◽  
White Men ◽  
The United States ◽  
Oral Tongue ◽  
Men And Women ◽  
Oral Tongue Cancer ◽  
Rising Incidence

NOVEL ADVANCES IN STAGING AND GRADING OF EARLY ORAL TONGUE CANCER: A MULTICENTER STUDY

2021 ◽  
Vol 132 (1) ◽  
pp. e4-e5
Author(s):  
A Almangush ◽  
RD Coletta ◽  
AA Mäkitie ◽  
T Salo ◽  
I Leivo
Keyword(s):  
Multicenter Study ◽  
Tongue Cancer ◽  
Oral Tongue ◽  
Oral Tongue Cancer

PO-0809: Lymph flow guided radiotherapy for oral tongue cancer: histological verification of the concept

2020 ◽  
Vol 152 ◽  
pp. S439
Author(s):  
S. Novikov ◽  
P. Krzhivitckiy ◽  
Z. Radgabova ◽  
S. Kanaev ◽  
M. Kotov ◽  
...  
Keyword(s):  
Tongue Cancer ◽  
Lymph Flow ◽  
Oral Tongue ◽  
Oral Tongue Cancer ◽  
Histological Verification

scholarly journals Clinical outcomes for T1-2N0-1 oral tongue cancer patients underwent surgery with and without postoperative radiotherapy

2010 ◽  
Vol 5 (1) ◽  
pp. 43 ◽  
Author(s):  
Su Jung Shim ◽  
Jihye Cha ◽  
Woong Sub Koom ◽  
Gwi Eon Kim ◽  
Chang Geol Lee ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Clinical Outcomes ◽  
Tongue Cancer ◽  
Postoperative Radiotherapy ◽  
Oral Tongue ◽  
Oral Tongue Cancer

R004: Expression of Apoptosis-Relate Proteins in Oral Tongue Cancer

2006 ◽  
Vol 135 (2_suppl) ◽  
pp. P105-P106
Author(s):  
Hyung-Cheol Jo ◽  
Chang-Su Park ◽  
Mu-Hyun Kans ◽  
Min-Hee Jans ◽  
Hi-Boong Kawk ◽  
...  
Keyword(s):  
Tongue Cancer ◽  
Oral Tongue ◽  
Oral Tongue Cancer
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