scholarly journals Changes in breath cycle sensing affect outcomes in upper airway stimulation in sleep apnea

2020 ◽  
Vol 5 (2) ◽  
pp. 326-329 ◽  
Author(s):  
Armin Steffen ◽  
J. Ulrich Sommer ◽  
Kingman Strohl ◽  
Katrin Hasselbacher ◽  
Maria V. Suurna ◽  
...  
Keyword(s):  
Sleep Apnea ◽  
Upper Airway ◽  
Upper Airway Stimulation ◽  
Breath Cycle

Upper Airway Stimulation Therapy for Obstructive Sleep Apnea

2021 ◽  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Upper Airway ◽  
Novel Therapy ◽  
Upper Airway Stimulation ◽  
Current State ◽  
Obstructive Sleep ◽  
Long Term Follow Up ◽  
Physician Extenders ◽  
Primary Care Practitioners

Upper Airway Stimulation Therapy for Obstructive Sleep Apnea provides the current state of knowledge regarding this novel therapy. It reviews the pathophysiologic basis of sleep apnea and the specific mechanism by which upper airway stimulation provides airway support in this disorder. It also provides practical insights into this therapy related to patient selection, clinical outcomes, surgical technique, long-term follow-up, and adverse events and offers recommendations for those aspiring to develop an upper airway stimulation program. It provides an overview of unique populations and circumstances that may extend the utility of the procedure, and that may provide challenges in management, as well as thoughts on the future of this technology. This textbook is intended for all practitioners who have interest or care for sleep disordered breathing, including sleep medicine physicians, pulmonologists, otolaryngologists, primary care practitioners, as well as physician extenders.

scholarly journals Sleep Apnea, Hypertension and the Sympathetic Nervous System in the Adult Population

2020 ◽  
Vol 9 (2) ◽  
pp. 591 ◽  
Author(s):  
Shreyas Venkataraman ◽  
Soumya Vungarala ◽  
Naima Covassin ◽  
Virend K. Somers
Keyword(s):  
Nervous System ◽  
Sleep Apnea ◽  
Sympathetic Nervous System ◽  
Adult Population ◽  
Management Strategies ◽  
Upper Airway ◽  
Upper Airway Stimulation ◽  
Neurogenic Hypertension ◽  
Pathogenic Mechanisms ◽  
Sympathetic Nervous

Sleep apnea is very common in patients with cardiovascular disease, especially in patients with hypertension. Over the last few decades a number of discoveries have helped support a causal relationship between the two and even resistant hypertension. The role neurogenic mechanisms play has gathered more attention in the recent past due to their immediate bedside utility. Several innovative discoveries in pathogenesis including those exploring the role of baroreflex gain, cardiovascular variability, chemoreceptor reflex activation and the sympathetic nervous system have emerged. In this review, we discuss the epidemiology of sleep apnea and hypertension and the pathogenic mechanisms contributing to neurogenic hypertension. Furthermore, recent management strategies in addition to continuous positive airway pressure (CPAP), such as upper airway stimulation and renal denervation that target these pathogenic mechanisms, are also discussed.

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