Single, high‐dose local injection of bFGF improves thyroarytenoid muscle atrophy after paralysis

2019 ◽  
Vol 130 (1) ◽  
pp. 159-165 ◽  
Author(s):  
Takao Goto ◽  
Rumi Ueha ◽  
Taku Sato ◽  
Yoko Fujimaki ◽  
Takaharu Nito ◽  
...  
Keyword(s):  
Muscle Atrophy ◽  
Local Injection ◽  
High Dose ◽  
Single High Dose ◽  
Thyroarytenoid Muscle

A single high dose of dexamethasone increases GAP-43 and synaptophysin in the hippocampus of aged rats

2017 ◽  
Vol 98 ◽  
pp. 62-69 ◽  
Author(s):  
Vesna Tesic ◽  
Milka Perovic ◽  
Ivan Zaletel ◽  
Mirna Jovanovic ◽  
Nela Puskas ◽  
...  
Keyword(s):  
High Dose ◽  
Aged Rats ◽  
Single High Dose

Effect of single high dose of spinal clonidine under normal and neuropathic conditions

2007 ◽  
Vol 24 (Supplement 39) ◽  
pp. 176
Author(s):  
M. Docquier ◽  
V. Collet ◽  
M. De Kock ◽  
P. Lavandhomme
Keyword(s):  
High Dose ◽  
Single High Dose

scholarly journals Microbiologic and Immunologic Evaluation of a Single High Dose of Azithromycin for Treatment of Experimental Mycoplasma pneumoniae Pneumonia

2005 ◽  
Vol 49 (9) ◽  
pp. 3970-3973 ◽  
Author(s):  
Ana María Ríos ◽  
Mónica Fonseca-Aten ◽  
Asunción Mejías ◽  
Susana Chávez-Bueno ◽  
Kathy Katz ◽  
...  
Keyword(s):  
Mycoplasma Pneumoniae ◽  
High Dose ◽  
Single High Dose ◽  
Cytokines And Chemokines ◽  
Lung Histopathology ◽  
Mycoplasma Pneumoniae Pneumonia

ABSTRACT We evaluated the efficacy of azithromycin therapy given as a single high dose or divided over 5 days for the treatment of mild experimental Mycoplasma pneumoniae pneumonia. Although both azithromycin regimens significantly reduced quantitative cultures, lung histopathology, and pulmonary cytokines and chemokines, there were no significant differences between the two regimens.

scholarly journals Single High-Dose Vitamin D Supplementation as an Approach for Reducing Ultramarathon-Induced Inflammation: A Double-Blind Randomized Controlled Trial

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1280
Author(s):  
Jan Mieszkowski ◽  
Andżelika Borkowska ◽  
Błażej Stankiewicz ◽  
Andrzej Kochanowicz ◽  
Bartłomiej Niespodziński ◽  
...  
Keyword(s):  
Vitamin D ◽  
Inflammatory Marker ◽  
Controlled Trial ◽  
Vitamin D Supplementation ◽  
Oncostatin M ◽  
Control Group ◽  
High Dose ◽  
Double Blind ◽  
Single High Dose ◽  
High Dose Vitamin

Purpose: A growing number of studies indicate the importance of vitamin D supplementation for sports performance. However, the effects of a single high-dose vitamin D supplementation on ultramarathon-induced inflammation have not been investigated. We here analyzed the effect of a single high-dose vitamin D supplementation on the inflammatory marker levels in ultramarathon runners after an ultramarathon run (maximal run 240 km). Methods: In the study, 35 runners (amateurs) were assigned into two groups: single high-dose vitamin D supplementation group, administered vitamin D (150,000 IU) in vegetable oil 24 h before the start of the run (n = 16); and placebo group (n = 19). Blood was collected for analysis 24 h before, immediately after, and 24 h after the run. Results: Serum 25(OH)D levels were significantly increased after the ultramarathon in both groups. The increase was greater in the vitamin D group than in the control group. Based on post-hoc and other analyses, the increase in interleukin 6 and 10, and resistin levels immediately after the run was significantly higher in runners in the control group than that in those in the supplementation group. Leptin, oncostatin M, and metalloproteinase tissue inhibitor levels were significantly decreased in both groups after the run, regardless of the supplementation. Conclusions: Ultramarathon significantly increases the serum 25(OH)D levels. Attenuation of changes in interleukin levels upon vitamin D supplementation confirmed that vitamin D has anti-inflammatory effect on exercise-induced inflammation.

Cardiovascular effects of a single high dose of dilazep by oral route

1986 ◽  
Vol 11 (3) ◽  
pp. 337-348 ◽  
Author(s):  
Giovanni V. Ibba ◽  
Pierfranco Terrosu ◽  
Vittorio Franceschino ◽  
Gianna M. Contini
Keyword(s):  
Cardiovascular Effects ◽  
Oral Route ◽  
High Dose ◽  
Single High Dose

Ventilatory effects of single, high-dose triazolam in awake human subjects

1988 ◽  
Vol 44 (6) ◽  
pp. 684-689 ◽  
Author(s):  
James B Skatrud ◽  
Robert L Begle ◽  
Michael A Busch
Keyword(s):  
Human Subjects ◽  
High Dose ◽  
Single High Dose ◽  
Ventilatory Effects

scholarly journals Advantages of Repeated Low Dose against Single High Dose of Kainate in C57BL/6J Mouse Model of Status Epilepticus: Behavioral and Electroencephalographic Studies

PLoS ONE ◽  
2014 ◽  
Vol 9 (5) ◽  
pp. e96622 ◽  
Author(s):  
Karen Tse ◽  
Sreekanth Puttachary ◽  
Edward Beamer ◽  
Graeme J. Sills ◽  
Thimmasettappa Thippeswamy
Keyword(s):  
Status Epilepticus ◽  
Mouse Model ◽  
Low Dose ◽  
High Dose ◽  
Single High Dose

scholarly journals Single high-dose (45 mg) infusions of aminohydroxypropylidene diphosphonate for severe malignant hypercalcemia

Cancer ◽  
1989 ◽  
Vol 64 (6) ◽  
pp. 1358-1361 ◽  
Author(s):  
Kathryn A. Mannix ◽  
James Carmichael ◽  
Adrian L. Harris ◽  
Brian M. J. Cantwell
Keyword(s):  
High Dose ◽  
Single High Dose
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