Human laryngeal sensory receptor mapping illuminates the mechanisms of laryngeal adductor reflex control

2018 ◽  
Vol 128 (11) ◽  
pp. E365-E370 ◽  
Author(s):  
Catherine F. Sinclair ◽  
Maria J. Téllez ◽  
Sedat Ulkatan
Keyword(s):  
Sensory Receptor ◽  
Receptor Mapping ◽  
Reflex Control ◽  
Laryngeal Adductor Reflex

Vergleich von Blutfluß und Benzodiazepin-Rezeptorverteilung bei fokaler Epilepsie: Vorläufige Ergebnisse einer SPECT-Studie

1989 ◽  
Vol 28 (05) ◽  
pp. 181-186
Author(s):  
A. Ludolph ◽  
O. Schober ◽  
G. Lottes ◽  
I. Böttger ◽  
H.-F. Beer ◽  
...  
Keyword(s):  
Human Brain ◽  
Receptor Binding ◽  
Brain Area ◽  
Brain Perfusion ◽  
Partial Epilepsy ◽  
Cerebral Lesion ◽  
Receptor Ligand ◽  
Receptor Mapping ◽  
Hmpao Spect ◽  
99Mtc Hmpao

99mTc-HMPAO-SPECT and SPECT with the 123I-labelled benzodiazepine (Bz) receptor ligand Ro 16-0154 were performed in 10 patients suffering from partial epilepsy, without cerebral lesion in MRT or CT. 2 h p.i. of Ro 16-0154 the distribution of activity correlated with the known distribution of Bz- receptors in the human brain. Perfusion and receptor-binding were found decreased in 7 patients of each study in the suspicious brain-area. 123l-labelled Ro 16-0154 is suitable for Bz-receptor mapping by SPECT. The decrease of Bz-receptor binding in epileptic foci, as described in PET-studies, was also detected by SPECT in 7 of 10 patients.

Nano-Mechanics and Membrane Receptor Mapping of CD8 + T Cells (Supplementry Material)

2009 ◽  
Vol 5 (4) ◽  
pp. 465-469
Author(s):  
Yangzhe Wu ◽  
Yi Hu ◽  
Hongsong Lu ◽  
Jiye Cai ◽  
Xianhui He ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Membrane Receptor ◽  
Receptor Mapping

Sensory Transduction

2019 ◽  
Author(s):  
Gordon L. Fain
Keyword(s):  
Ion Channels ◽  
Receptor Cell ◽  
Electrical Response ◽  
Second Messengers ◽  
Sensory Transduction ◽  
Sensory Receptor ◽  
Signal Pathways ◽  
Sense Organs ◽  
Sensory Physiology ◽  
Effector Molecules

Sensory Transduction provides a thorough and easily accessible introduction to the mechanisms that each of the different kinds of sensory receptor cell uses to convert a sensory stimulus into an electrical response. Beginning with an introduction to methods of experimentation, sensory specializations, ion channels, and G-protein cascades, it provides up-to-date reviews of all of the major senses, including touch, hearing, olfaction, taste, photoreception, and the “extra” senses of thermoreception, electroreception, and magnetoreception. By bringing mechanisms of all of the senses together into a coherent treatment, it facilitates comparison of ion channels, metabotropic effector molecules, second messengers, and other components of signal pathways that are common themes in the physiology of the different sense organs. With its many clear illustrations and easily assimilated exposition, it provides an ideal introduction to current research for the professional in neuroscience, as well as a text for an advanced undergraduate or graduate-level course on sensory physiology.

scholarly journals The reciprocal jaw-muscle reflexes elicited by anterior- and back-tooth-contacts—a perspective to explain the control of the masticatory muscles

BDJ Open ◽  
2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Lauri Vaahtoniemi
Keyword(s):  
Masticatory Muscles ◽  
Food Bolus ◽  
Dental Patients ◽  
Adductor Muscles ◽  
Jaw Muscle ◽  
Class 1 ◽  
Reflex Control ◽  
Control Hypothesis ◽  
Muscle Reflexes ◽  
Inhibitory Reflex

Abstract Aims Tooth-contact sensations are considered essential to boost jaw adductor muscles during mastication. However, no previous studies have explained the importance of the inhibitory reflex of human anterior-tooth (ANT)-contacts in mastication. Here I present the “reciprocal reflex-control-hypothesis” of mammalian mastication. Subjects and setting of the study I demonstrate the hypothesis with the live kinematics of free jaw-closures as inferred from T-Scan recordings of dental patients. Results The jaw-closures started with negligible force, predominantly with ANT-contacts (the AF-bites). The first ANT-contact inhibited the first kinematic tilt of the mandible, whereas the bites starting from a back-tooth (BAT)-contact (the BF-bites) accelerated the first tilt. The second tilt established a low-force static tripod of the ANT- and bilateral BAT-contacts for a fixed mandible-maxilla relation. Thereafter, semi-static bite force increased rapidly, relatively more in the BAT-area. Discussion and Conclusions In the vertical-closure phase of chewing, the primate joint-fulcrum (class 3 lever) conflicts with the food-bolus-fulcrum in the BAT-area (class 1 lever). The resilient class 3 and 1 lever systems are superseded by an almost static mechanically more advantageous class 2 lever with a more rigid fulcrum at the most anterior ANT-contact. For humans, the class 2 levered delivery of force also enables forceful horizontal food grinding to be extended widely to the BAT-area.

Unforeseen clinical outcome for laryngeal adductor reflex loss during intraaxial brainstem surgery

2019 ◽  
Vol 130 (10) ◽  
pp. 2001-2002 ◽  
Author(s):  
Ana Mirallave Pescador ◽  
M. Ángeles Sánchez Roldán ◽  
Maria J. Téllez ◽  
Catherine F. Sinclair ◽  
Sedat Ulkatan
Keyword(s):  
Clinical Outcome ◽  
Brainstem Surgery ◽  
Laryngeal Adductor Reflex

Graphics computer-aided receptor mapping as a predictive tool for drug design: development of potent, selective, and stereospecific ligands for the 5-HT1A receptor

1988 ◽  
Vol 31 (6) ◽  
pp. 1087-1093 ◽  
Author(s):  
Marcel F. Hibert ◽  
Maurice W. Gittos ◽  
Derek N. Middlemiss ◽  
Anis K. Mir ◽  
John R. Fozard
Keyword(s):  
Drug Design ◽  
Design Development ◽  
Predictive Tool ◽  
Receptor Mapping ◽  
Computer Aided
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