Differences in clinical characteristics and prognosis of sudden low- and high-frequency hearing loss

2016 ◽  
Vol 127 (8) ◽  
pp. 1878-1884 ◽  
Author(s):  
Oak-Sung Choo ◽  
Suk Min Yang ◽  
Hun Yi Park ◽  
Jong Bin Lee ◽  
Jeong Hun Jang ◽  
...  
Keyword(s):  
Hearing Loss ◽  
High Frequency ◽  
Clinical Characteristics ◽  
High Frequency Hearing Loss

Mutations in the MYO15A Gene Are a Significant Cause of Nonsyndromic Hearing Loss

2015 ◽  
Vol 124 (1_suppl) ◽  
pp. 158S-168S ◽  
Author(s):  
Maiko Miyagawa ◽  
Shin-ya Nishio ◽  
Mitsuru Hattori ◽  
Hideaki Moteki ◽  
Yumiko Kobayashi ◽  
...  
Keyword(s):  
Hearing Loss ◽  
High Frequency ◽  
Clinical Characteristics ◽  
Age At Onset ◽  
Massively Parallel ◽  
Nonsyndromic Hearing Loss ◽  
Congenital Hearing Loss ◽  
Progressive Hearing Loss ◽  
High Frequency Hearing Loss ◽  
Massively Parallel Dna Sequencing

Objectives: Screening for MYO15A mutations was carried out using a large cohort to clarify the frequency and clinical characteristics of patients with MYO15A (DFNB3) mutations in a hearing loss population. Methods: Genetic analysis of 63 previously reported deafness genes based on massively parallel DNA sequencing (MPS) in 1120 Japanese hearing loss patients from 53 otorhinolaryngology departments was performed. Detailed clinical features of the patients with MYO15A mutations were then collected and analyzed. Results: Eleven patients from 10 families were found to have compound heterozygosity for MYO15A. Audiograms showed profound or high frequency hearing loss, with some patients showing progressive hearing loss. Age at onset was found to vary from 0 to 14 years, which seemed to be associated with the mutation. Four children underwent bilateral cochlear implantation for congenital hearing loss, with all showing good results. Conclusion: Mutations in the MYO15A gene are a notable cause of nonsyndromic hearing loss. MPS technology successfully detected mutations in relatively rare deafness genes such as MYO15A.

Modified Earpieces and CROS for High Frequency Hearing Losses

1968 ◽  
Vol 11 (1) ◽  
pp. 204-218 ◽  
Author(s):  
Elizabeth Dodds ◽  
Earl Harford
Keyword(s):  
Hearing Loss ◽  
Hearing Aids ◽  
High Frequency ◽  
Hearing Aid ◽  
Sound Field ◽  
Intensity Level ◽  
Test Results ◽  
High Frequency Hearing Loss ◽  
Increased Sensitivity ◽  
Difficult Cases

Persons with a high frequency hearing loss are difficult cases for whom to find suitable amplification. We have experienced some success with this problem in our Hearing Clinics using a specially designed earmold with a hearing aid. Thirty-five cases with high frequency hearing losses were selected from our clinical files for analysis of test results using standard, vented, and open earpieces. A statistical analysis of test results revealed that PB scores in sound field, using an average conversational intensity level (70 dB SPL), were enhanced when utilizing any one of the three earmolds. This result was due undoubtedly to increased sensitivity provided by the hearing aid. Only the open earmold used with a CROS hearing aid resulted in a significant improvement in discrimination when compared with the group’s unaided PB score under earphones or when comparing inter-earmold scores. These findings suggest that the inclusion of the open earmold with a CROS aid in the audiologist’s armamentarium should increase his flexibility in selecting hearing aids for persons with a high frequency hearing loss.

scholarly journals Evaluating the Effectiveness of Earplugs in Preventing Noise-Induced Hearing Loss in an Auto Parts Factory in China

2021 ◽  
Vol 18 (13) ◽  
pp. 7190
Author(s):  
Wei Gong ◽  
Liangliang Zhao ◽  
Ling Li ◽  
Thais C. Morata ◽  
Wei Qiu ◽  
...  
Keyword(s):  
Hearing Loss ◽  
High Frequency ◽  
Health And Safety ◽  
Health Department ◽  
Detectable Effect ◽  
High Frequency Hearing Loss ◽  
Mandatory Requirement ◽  
Exposed Workers ◽  
Fit Testing ◽  
Auto Parts

A survey was administered to 385 noise-exposed workers from an auto parts factory and 1268 non-noise-exposed health department employees in China. Individual 8 h A-weighted equivalent sound levels (LAeq,8h), earplug personal attenuation ratings (PARs), and pure-tone audiometric tests were performed. The average LAeq,8h of noise-exposed workers was 87 dB (A) with a mean PAR of 7 dB. The prevalence of high-frequency hearing loss was 65% for noise-exposed workers and 33% for the non-noise-exposed employees. The use of earplugs had no observable effect on the prevalence of high-frequency hearing loss of the study participants (OR 0.964, 95% CI 0.925–1.005, p = 0.085). No significant relationship between the effectiveness offered by earplug use and high-frequency hearing thresholds at 3, 4, and 6 kHz was found (t = −1.54, p = 0.125). The mandatory requirement of earplug use without individualized training on how to wear HPDs correctly had no detectable effect on the prevention of hearing loss at the auto parts factory. The hearing conservation program at the surveyed factory was not effective. Periodic hearing tests, earplug fit testing, expanding the offer of different types of hearing protection, and employee education about the importance of protecting their hearing were recommended to the occupational health and safety program.

Caudal Pontine Reticular Formation of C57BL/6J Mice: Responses to Startle Stimuli, Inhibition by Tones, and Plasticity

1998 ◽  
Vol 79 (5) ◽  
pp. 2603-2614 ◽  
Author(s):  
Stephanie Carlson ◽  
James F. Willott
Keyword(s):  
Hearing Loss ◽  
Reticular Formation ◽  
Auditory System ◽  
Neural Plasticity ◽  
High Frequency ◽  
Acoustic Startle ◽  
Acoustic Startle Response ◽  
Pontine Reticular Formation ◽  
High Frequency Hearing Loss ◽  
Old Mice

Carlson, Stephanie and James F. Willott. Caudal pontine reticular formation of C57BL/6J mice: responses to startle stimuli, inhibition by tones, and plasticity. J. Neurophysiol. 79: 2603–2614, 1998. C57BL/6J (C57) mice were used to examine relationships between the behavioral acoustic startle response (ASR) and the responses of neurons in the caudal pontine reticular formation (PnC) in three contexts: 1) responses evoked by basic startle stimuli; 2) the prepulse inhibition (PPI) paradigm; and 3) the effects of high-frequency hearing loss and concomitant neural plasticity that occurs in middle-aged C57 mice. 1) Responses (evoked action potentials) of PnC neurons closely paralleled the ASR with respect to latency, threshold, and responses to rapidly presented stimuli. 2) “Neural PPI” (inhibition of responses evoked by a startle stimulus when preceded by a tone prepulse) was observed in all PnC neurons studied. 3) In PnC neurons of 6-mo-old mice with high-frequency (>20 kHz) hearing loss, neural PPI was enhanced with 12- and 4-kHz prepulses, as it is behaviorally. These are frequencies that have become “overrepresented” in the central auditory system of 6-mo-old C57 mice. Thus neural plasticity in the auditory system, induced by high-frequency hearing loss, is correlated with increased salience of the inhibiting tones in both behavioral and neural PPI paradigms.

scholarly journals High Frequency Hearing Loss and Hyperactivity in DUX4 Transgenic Mice

PLoS ONE ◽  
2016 ◽  
Vol 11 (3) ◽  
pp. e0151467 ◽  
Author(s):  
Abhijit Dandapat ◽  
Benjamin J. Perrin ◽  
Christine Cabelka ◽  
Maria Razzoli ◽  
James M. Ervasti ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Transgenic Mice ◽  
High Frequency ◽  
High Frequency Hearing Loss

scholarly journals Real-World Performance of a Reverse-Horn Vent

2005 ◽  
Vol 16 (09) ◽  
pp. 653-661
Author(s):  
Francis Kuk ◽  
Denise Keenan ◽  
Chi-Chuen Lau ◽  
Nick Dinulescu ◽  
Richard Cortez ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hearing Aids ◽  
High Frequency ◽  
Objective Measures ◽  
Subjective Ratings ◽  
High Frequency Hearing Loss ◽  
Speech In Noise ◽  
Objective Performance ◽  
Occlusion Effect

The present study compared differences in subjective and objective performance in completely-in-the-canal (CIC) hearing aids with conventional uniform 1.5 mm parallel vents and another with a reverse horn vent where the diameter increased from 1.5 mm on the lateral faceplate to 3 mm on the medial opening of the hearing aid. Nine hearing-impaired persons with a high-frequency hearing loss participated. The test battery included unaided in situ thresholds, amount of available gain before feedback, speech in quiet, speech in noise (HINT), subjective ratings of hollowness and tolerance, objective measures of the occlusion effect, and real-ear aided response. Results showed less available gain before feedback but less occlusion effect for subjective ratings and objective measures with the reverse horn vent. This type of vent design may be useful to increase the effective vent diameter of custom (including CIC) hearing aids.

Tinnitus Suppression Effect of Hearing Aids in Patients With High-frequency Hearing Loss

2019 ◽  
Vol 40 (7) ◽  
pp. 865-871 ◽  
Author(s):  
Natalia Yakunina ◽  
Woo Hyun Lee ◽  
Yoon-Jong Ryu ◽  
Eui-Cheol Nam
Keyword(s):  
Hearing Loss ◽  
Hearing Aids ◽  
High Frequency ◽  
High Frequency Hearing Loss ◽  
Suppression Effect
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